AutismKB 2.0

Annotation Detail for DPYSL3


View Evidences View Variants View Annotations
Basic Information Top
Gene Symbol:DPYSL3 ( CRMP-4,CRMP4,DRP-3,DRP3,LCRMP,ULIP,ULIP-1 )
Gene Full Name: dihydropyrimidinase-like 3
Band: 5q32
Quick LinksEntrez ID:1809; OMIM: 601168; Uniprot ID:DPYL3_HUMAN; ENSEMBL ID: ENSG00000113657; HGNC ID: 3015
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body21 / 70761296
blastocyst44 / 62319706
fetus142 / 564012251
neonate0 / 310970 
infant1 / 2362042
juvenile2 / 5555635
adult190 / 193912197
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma2 / 17475114
breast (mammary gland) tumor3 / 9417831
cervical tumor0 / 343660 
chondrosarcoma11 / 82823132
colorectal tumor8 / 11424670
esophageal tumor0 / 172900 
gastrointestinal tumor11 / 11936992
germ cell tumor27 / 263845102
glioma32 / 106883299
head and neck tumor11 / 13630280
kidney tumor6 / 6895987
leukemia0 / 958420 
liver tumor3 / 9635931
lung tumor10 / 10312796
lymphoma1 / 7175513
non-neoplasia12 / 97250123
normal374 / 3360307111
ovarian tumor6 / 7668278
pancreatic tumor11 / 104616105
primitive neuroectodermal tumor of the CNS8 / 12568063
prostate cancer3 / 10268029
retinoblastoma16 / 46356345
skin tumor7 / 12494956
soft tissue/muscle tissue tumor2 / 12519115
uterine tumor2 / 9025722
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue4 / 13106305
adrenal gland0 / 331970 
ascites0 / 400150 
bladder0 / 297570 
blood0 / 1234780 
bone12 / 71655167
bone marrow0 / 488010 
brain174 / 1100989158
cervix0 / 481710 
connective tissue10 / 14925566
ear0 / 162120 
embryonic tissue76 / 215722352
esophagus0 / 202090 
eye59 / 211054279
heart24 / 89626267
intestine18 / 23447276
kidney9 / 21177742
larynx2 / 2414582
liver3 / 20774314
lung65 / 336974192
lymph0 / 442700 
lymph node1 / 9161010
mammary gland3 / 15327119
mouth4 / 6705259
muscle4 / 10771537
nerve4 / 15768253
ovary10 / 10205197
pancreas16 / 21481274
parathyroid0 / 205390 
pharynx0 / 413280 
pituitary gland0 / 165850 
placenta11 / 28082539
prostate14 / 18934573
salivary gland3 / 20155148
skin10 / 21057447
spleen1 / 5395218
stomach11 / 96619113
testis28 / 33044284
thymus0 / 811310 
thyroid3 / 4747363
tonsil1 / 1699958
trachea2 / 5241338
umbilical cord0 / 136800 
uterus20 / 23287885
vascular5 / 5178096
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 201430_s_at
Cell line Expression level Expression bar
721_B_lymphoblasts6.4
Adipocyte5.25
AdrenalCortex5.9
Adrenalgland4.65
Amygdala7.35
Appendix6.35
AtrioventricularNode4.6
BDCA4+_DentriticCells5.5
Bonemarrow5.65
BronchialEpithelialCells5.2
CD105+_Endothelial5.35
CD14+_Monocytes5.7
CD19+_BCells(neg._sel.)5.6
CD33+_Myeloid6.7
CD34+6.55
CD4+_Tcells5.65
CD56+_NKCells6.05
CD71+_EarlyErythroid5.15
CD8+_Tcells4.9
CardiacMyocytes130.3
Caudatenucleus4.85
Cerebellum4.55
CerebellumPeduncles6.35
CiliaryGanglion4.45
CingulateCortex5.6
Colorectaladenocarcinoma5.45
DorsalRootGanglion4.65
FetalThyroid5.3
Fetalbrain29.5
Fetalliver4.75
Fetallung4.4
GlobusPallidus4.1
Heart7.65
Hypothalamus7.85
Kidney4.65
Leukemia_chronicMyelogenousK-5624.85
Leukemia_promyelocytic-HL-604.75
Leukemialymphoblastic(MOLT-4)4.25
Liver7.55
Lung5.9
Lymphnode4.7
Lymphoma_burkitts(Daudi)7.05
Lymphoma_burkitts(Raji)8
MedullaOblongata5.05
OccipitalLobe4.8
OlfactoryBulb4.2
Ovary5.25
Pancreas4.45
PancreaticIslet7.35
ParietalLobe5.9
Pituitary6.3
Placenta5.5
Pons5.3
PrefrontalCortex6.85
Prostate13.8
Salivarygland4.45
SkeletalMuscle7
Skin4.65
SmoothMuscle63.45
Spinalcord6.2
SubthalamicNucleus5.05
SuperiorCervicalGanglion7.65
TemporalLobe5.05
Testis5.55
TestisGermCell4.5
TestisIntersitial4.6
TestisLeydigCell5.4
TestisSeminiferousTubule4.55
Thalamus5.7
Thymus4.15
Thyroid6.65
Tongue5.6
Tonsil5.35
Trachea5.2
TrigeminalGanglion6.75
Uterus7.1
UterusCorpus5.15
WholeBlood5.85
Wholebrain4.55
colon12.9
pineal_day30.72
pineal_night46.24
retina43.275
small_intestine15.2
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: A_23_P7528
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala5.9 ± 0.44
Basal Forebrain6.39 ± 0.37
Basal Part of Pons5.78 ± 0.25
Cerebellar Cortex5.04 ± 0.26
Cerebellar Nuclei5.1 ± 0.76
Claustrum6.28 ± 0.54
Epithalamus6.91 ± 0.65
Frontal Lobe5.64 ± 0.66
Globus Pallidus7.36 ± 0.34
Hypothalamus6.79 ± 0.18
Insula6.09 ± 0.43
Limbic Lobe5.56 ± 0.87
Mesencephalon5.71 ± 0.76
Myelencephalon5.87 ± 0.65
Occipital Lobe4.85 ± 0.79
Parietal Lobe5.36 ± 0.61
Pontine Tegmentum5.62 ± 0.66
Striatum5.96 ± 0.62
Subthalamus6.31 ± 0.3
Temporal Lobe5.82 ± 0.6
Thalamus5.34 ± 0.58
White Matter5.34 ± 0.26
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Dpysl3CBCerebellum1.78
1.97
Dpysl3CTXCerebral cortex0.66
0.65
Dpysl3HIPHippocampal region1.23
1.05
Dpysl3HPFHippocampal formation1.17
0.9
Dpysl3HYHypothalamus0.67
0.46
Dpysl3LSXLateral septal complex0.89
1.56
Dpysl3MBMidbrain1.85
1.81
Dpysl3MYMedulla7.82
9.47
Dpysl3OLFOlfactory bulb7.32
7.75
Dpysl3PPons5.98
7.18
Dpysl3PALPallidum0.37
0.3
Dpysl3RHPRetrohippocampal region1.15
0.76
Dpysl3sAMYStriatum-like amygdalar nuclei0.16
0.06
Dpysl3STRStriatum0.67
0.83
Dpysl3STRdStriatum dorsal region0.6
0.78
Dpysl3STRvStriatum ventral region0.98
0.97
Dpysl3THThalamus0.75
0.51
Peptide Top
Peptide Name Peptide Lengh Peptide Start Peptide End Peptide Sequence Source
DPYL3_HUMAN_2 10 2 11 SYQGKKNIPR PRIDE
DPYL3_HUMAN_211 27 211 237 MLEMGITGPEGHVLSRPEELEAEAVFR PRIDE
DPYL3_HUMAN_258 10 258 267 SAADLISQAR PRIDE
DPYL3_HUMAN_374 16 374 389 MDENQFVAVTSTNAAK PRIDE
DPYL3_HUMAN_390 7 390 396 IFNLYPR PRIDE
DPYL3_HUMAN_424 17 424 440 NHQSAAEYNIFEGMELR PRIDE
DPYL3_HUMAN_440 11 440 450 GAPLVVICQGK PRIDE
DPYL3_HUMAN_496 15 496 510 GMYDGPVFDLTTTPK PRIDE
DPYL3_HUMAN_64 18 64 81 MVIPGGIDVHTHFQMPYK PRIDE
PAp00063486 16 239 254 AITIASQTNCPLYVTK Peptide Atlas

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


Copyright © 2017, Center for Bioinformatics , Peking University | All Rights Reserved