AutismKB 2.0

Annotation Detail for DTNA


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Basic Information Top
Gene Symbol:DTNA ( D18S892E,DRP3,DTN,DTN-A,FLJ96209,LVNC1 )
Gene Full Name: dystrobrevin, alpha
Band: 18q12.1
Quick LinksEntrez ID:1837; OMIM: 601239; Uniprot ID:DTNA_HUMAN; ENSEMBL ID: ENSG00000134769; HGNC ID: 3057
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body3 / 7076142
blastocyst0 / 623190 
fetus39 / 56401269
neonate1 / 3109732
infant0 / 236200 
juvenile3 / 5555653
adult126 / 193912164
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma0 / 174750 
breast (mammary gland) tumor0 / 941780 
cervical tumor0 / 343660 
chondrosarcoma0 / 828230 
colorectal tumor0 / 1142460 
esophageal tumor0 / 172900 
gastrointestinal tumor0 / 1193690 
germ cell tumor25 / 26384594
glioma18 / 106883168
head and neck tumor8 / 13630258
kidney tumor4 / 6895958
leukemia0 / 958420 
liver tumor1 / 9635910
lung tumor0 / 1031270 
lymphoma0 / 717550 
non-neoplasia14 / 97250143
normal351 / 3360307104
ovarian tumor1 / 7668213
pancreatic tumor2 / 10461619
primitive neuroectodermal tumor of the CNS0 / 1256800 
prostate cancer1 / 1026809
retinoblastoma0 / 463560 
skin tumor1 / 1249498
soft tissue/muscle tissue tumor4 / 12519131
uterine tumor1 / 9025711
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland0 / 331970 
ascites0 / 400150 
bladder0 / 297570 
blood0 / 1234780 
bone0 / 716550 
bone marrow0 / 488010 
brain308 / 1100989279
cervix0 / 481710 
connective tissue4 / 14925526
ear0 / 162120 
embryonic tissue3 / 21572213
esophagus0 / 202090 
eye13 / 21105461
heart15 / 89626167
intestine4 / 23447217
kidney4 / 21177718
larynx1 / 2414541
liver2 / 2077439
lung9 / 33697426
lymph0 / 442700 
lymph node0 / 916100 
mammary gland2 / 15327113
mouth4 / 6705259
muscle6 / 10771555
nerve2 / 15768126
ovary0 / 1020510 
pancreas3 / 21481213
parathyroid0 / 205390 
pharynx0 / 413280 
pituitary gland1 / 1658560
placenta9 / 28082532
prostate3 / 18934515
salivary gland0 / 201550 
skin2 / 2105749
spleen1 / 5395218
stomach0 / 966190 
testis14 / 33044242
thymus0 / 811310 
thyroid5 / 47473105
tonsil0 / 169990 
trachea3 / 5241357
umbilical cord0 / 136800 
uterus7 / 23287830
vascular1 / 5178019
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 205741_s_at
Cell line Expression level Expression bar
721_B_lymphoblasts5.1
Adipocyte4.05
AdrenalCortex4.5
Adrenalgland3.5
Amygdala10.5
Appendix4.25
AtrioventricularNode3.5
BDCA4+_DentriticCells4.55
Bonemarrow4.1
BronchialEpithelialCells4.15
CD105+_Endothelial4.25
CD14+_Monocytes4.45
CD19+_BCells(neg._sel.)4.4
CD33+_Myeloid5.45
CD34+5.4
CD4+_Tcells4.45
CD56+_NKCells4.9
CD71+_EarlyErythroid3.95
CD8+_Tcells4.05
CardiacMyocytes5.65
Caudatenucleus4.35
Cerebellum3.45
CerebellumPeduncles4.8
CiliaryGanglion3
CingulateCortex4.3
Colorectaladenocarcinoma4.15
DorsalRootGanglion3.3
FetalThyroid4.1
Fetalbrain34.75
Fetalliver3.6
Fetallung3.45
GlobusPallidus3.05
Heart5.6
Hypothalamus14.75
Kidney3.4
Leukemia_chronicMyelogenousK-5623.75
Leukemia_promyelocytic-HL-603.7
Leukemialymphoblastic(MOLT-4)3.25
Liver5.5
Lung4.55
Lymphnode3.6
Lymphoma_burkitts(Daudi)5.3
Lymphoma_burkitts(Raji)5.95
MedullaOblongata3.8
OccipitalLobe4.4
OlfactoryBulb5.35
Ovary2.8
Pancreas3.35
PancreaticIslet4.45
ParietalLobe4.5
Pituitary4.85
Placenta4.25
Pons4
PrefrontalCortex18.55
Prostate4.85
Salivarygland3.4
SkeletalMuscle5.15
Skin3.3
SmoothMuscle4.65
Spinalcord56.2
SubthalamicNucleus3.9
SuperiorCervicalGanglion5.2
TemporalLobe3.85
Testis3.55
TestisGermCell3.5
TestisIntersitial3.5
TestisLeydigCell4.2
TestisSeminiferousTubule3.55
Thalamus4.35
Thymus3.25
Thyroid5.2
Tongue4.25
Tonsil4.1
Trachea3.45
TrigeminalGanglion4.35
Uterus3.45
UterusCorpus3.85
WholeBlood4.55
Wholebrain3.6
colon4.25
pineal_day9.58
pineal_night5.48
retina30.25
small_intestine4.1
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: CUST_6757_PI416261804
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala7.83 ± 0.24
Basal Forebrain8.18 ± 0.28
Basal Part of Pons7.21 ± 0.22
Cerebellar Cortex7.69 ± 0.27
Cerebellar Nuclei7.46 ± 0.31
Claustrum7.49 ± 0.34
Epithalamus8.42 ± 0.34
Frontal Lobe7.57 ± 0.37
Globus Pallidus8.83 ± 0.38
Hypothalamus7.89 ± 0.42
Insula7.58 ± 0.33
Limbic Lobe7.65 ± 0.41
Mesencephalon7.86 ± 0.37
Myelencephalon7.76 ± 0.37
Occipital Lobe7.85 ± 0.41
Parietal Lobe7.67 ± 0.35
Pontine Tegmentum7.64 ± 0.3
Striatum7.68 ± 0.4
Subthalamus7.45 ± 0.31
Temporal Lobe7.55 ± 0.26
Thalamus7.69 ± 0.27
White Matter7.42 ± 0.36
Mouse Brain ISH
Peptide Top
Peptide Name Peptide Lengh Peptide Start Peptide End Peptide Sequence Source
PAp00497716 13 495 507 LEHEQASQPTPEK Peptide Atlas

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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