AutismKB 2.0

Annotation Detail for DTX1


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Basic Information Top
Gene Symbol:DTX1 ( hDx-1 )
Gene Full Name: deltex homolog 1 (Drosophila)
Band: 12q24.13
Quick LinksEntrez ID:1840; OMIM: 602582; Uniprot ID:DTX1_HUMAN; ENSEMBL ID: ENSG00000135144; HGNC ID: 3060
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body0 / 707610 
blastocyst0 / 623190 
fetus5 / 5640128
neonate0 / 310970 
infant0 / 236200 
juvenile4 / 5555671
adult17 / 19391218
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma0 / 174750 
breast (mammary gland) tumor0 / 941780 
cervical tumor0 / 343660 
chondrosarcoma0 / 828230 
colorectal tumor0 / 1142460 
esophageal tumor0 / 172900 
gastrointestinal tumor0 / 1193690 
germ cell tumor0 / 2638450 
glioma1 / 1068839
head and neck tumor1 / 1363027
kidney tumor1 / 6895914
leukemia3 / 9584231
liver tumor0 / 963590 
lung tumor0 / 1031270 
lymphoma22 / 71755306
non-neoplasia1 / 9725010
normal41 / 336030712
ovarian tumor0 / 766820 
pancreatic tumor1 / 1046169
primitive neuroectodermal tumor of the CNS0 / 1256800 
prostate cancer0 / 1026800 
retinoblastoma3 / 4635664
skin tumor0 / 1249490 
soft tissue/muscle tissue tumor1 / 1251917
uterine tumor2 / 9025722
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue1 / 1310676
adrenal gland0 / 331970 
ascites0 / 400150 
bladder0 / 297570 
blood0 / 1234780 
bone0 / 716550 
bone marrow0 / 488010 
brain4 / 11009893
cervix0 / 481710 
connective tissue0 / 1492550 
ear0 / 162120 
embryonic tissue0 / 2157220 
esophagus0 / 202090 
eye6 / 21105428
heart0 / 896260 
intestine0 / 2344720 
kidney1 / 2117774
larynx1 / 2414541
liver0 / 2077430 
lung6 / 33697417
lymph17 / 44270384
lymph node19 / 91610207
mammary gland1 / 1532716
mouth0 / 670520 
muscle0 / 1077150 
nerve1 / 1576863
ovary0 / 1020510 
pancreas1 / 2148124
parathyroid0 / 205390 
pharynx0 / 413280 
pituitary gland0 / 165850 
placenta4 / 28082514
prostate0 / 1893450 
salivary gland0 / 201550 
skin0 / 2105740 
spleen1 / 5395218
stomach0 / 966190 
testis0 / 3304420 
thymus0 / 811310 
thyroid0 / 474730 
tonsil3 / 16999176
trachea0 / 524130 
umbilical cord0 / 136800 
uterus2 / 2328788
vascular0 / 517800 
Microarray in BioGPS Top
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: A_23_P36567
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala3.37 ± 0.8
Basal Forebrain3.1 ± 0.62
Basal Part of Pons2.61 ± 0.48
Cerebellar Cortex2.89 ± 0.6
Cerebellar Nuclei3.13 ± 0.55
Claustrum3.51 ± 0.6
Epithalamus2.68 ± 0.63
Frontal Lobe3 ± 0.64
Globus Pallidus3.26 ± 0.64
Hypothalamus2.77 ± 0.4
Insula2.7 ± 0.67
Limbic Lobe2.95 ± 0.71
Mesencephalon3.15 ± 0.84
Myelencephalon3.02 ± 0.63
Occipital Lobe3.03 ± 0.77
Parietal Lobe2.99 ± 0.68
Pontine Tegmentum3.08 ± 0.69
Striatum3.15 ± 0.76
Subthalamus2.87 ± 0.75
Temporal Lobe3.06 ± 0.68
Thalamus2.94 ± 0.58
White Matter2.07 ± 0.46
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Dtx1CBCerebellum91.12
94.1
Dtx1CTXCerebral cortex98.43
54.24
Dtx1HIPHippocampal region95.57
58.28
Dtx1HPFHippocampal formation100
67.55
Dtx1HYHypothalamus93.75
58.54
Dtx1LSXLateral septal complex70.78
29.09
Dtx1MBMidbrain94.77
56.64
Dtx1MYMedulla87.98
69.77
Dtx1OLFOlfactory bulb100
66.24
Dtx1PPons72.48
55.54
Dtx1PALPallidum73.12
44.03
Dtx1RHPRetrohippocampal region100
81.6
Dtx1sAMYStriatum-like amygdalar nuclei83.35
43.18
Dtx1STRStriatum32.98
16.15
Dtx1STRdStriatum dorsal region19.81
10.37
Dtx1STRvStriatum ventral region37.03
16.23
Dtx1THThalamus86.36
44.61
Peptide Top
Peptide Name Peptide Lengh Peptide Start Peptide End Peptide Sequence Source
PAp00008771 17 37 53 WRPYTATVCHHIENVLK Peptide Atlas

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018