AutismKB 2.0

Annotation Detail for ECM2


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Basic Information Top
Gene Symbol:ECM2 ( MGC126355,MGC126356 )
Gene Full Name: extracellular matrix protein 2, female organ and adipocyte specific
Band: 9q22.31
Quick LinksEntrez ID:1842; OMIM: 603479; Uniprot ID:ECM2_HUMAN; ENSEMBL ID: ENSG00000106823; HGNC ID: 3154
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body0 / 707610 
blastocyst1 / 6231916
fetus8 / 56401214
neonate0 / 310970 
infant0 / 236200 
juvenile1 / 5555617
adult31 / 193912115
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma0 / 174750 
breast (mammary gland) tumor1 / 9417810
cervical tumor0 / 343660 
chondrosarcoma2 / 8282324
colorectal tumor0 / 1142460 
esophageal tumor0 / 172900 
gastrointestinal tumor1 / 1193698
germ cell tumor0 / 2638450 
glioma0 / 1068830 
head and neck tumor2 / 13630214
kidney tumor1 / 6895914
leukemia0 / 958420 
liver tumor1 / 9635910
lung tumor0 / 1031270 
lymphoma0 / 717550 
non-neoplasia13 / 97250133
normal59 / 336030717
ovarian tumor0 / 766820 
pancreatic tumor2 / 10461619
primitive neuroectodermal tumor of the CNS0 / 1256800 
prostate cancer1 / 1026809
retinoblastoma0 / 463560 
skin tumor0 / 1249490 
soft tissue/muscle tissue tumor0 / 1251910 
uterine tumor2 / 9025722
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland1 / 3319730
ascites0 / 400150 
bladder0 / 297570 
blood0 / 1234780 
bone4 / 7165555
bone marrow0 / 488010 
brain19 / 110098917
cervix0 / 481710 
connective tissue12 / 14925580
ear0 / 162120 
embryonic tissue1 / 2157224
esophagus0 / 202090 
eye1 / 2110544
heart1 / 8962611
intestine0 / 2344720 
kidney9 / 21177742
larynx1 / 2414541
liver4 / 20774319
lung5 / 33697414
lymph0 / 442700 
lymph node0 / 916100 
mammary gland4 / 15327126
mouth0 / 670520 
muscle5 / 10771546
nerve1 / 1576863
ovary1 / 1020519
pancreas2 / 2148129
parathyroid0 / 205390 
pharynx1 / 4132824
pituitary gland0 / 165850 
placenta1 / 2808253
prostate1 / 1893455
salivary gland0 / 201550 
skin1 / 2105744
spleen0 / 539520 
stomach2 / 9661920
testis7 / 33044221
thymus2 / 8113124
thyroid1 / 4747321
tonsil0 / 169990 
trachea5 / 5241395
umbilical cord0 / 136800 
uterus4 / 23287817
vascular4 / 5178077
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 206101_at
Cell line Expression level Expression bar
721_B_lymphoblasts7.6
Adipocyte75.2
AdrenalCortex12.5
Adrenalgland6.7
Amygdala7.55
Appendix40.55
AtrioventricularNode94.45
BDCA4+_DentriticCells6.95
Bonemarrow10.1
BronchialEpithelialCells6.8
CD105+_Endothelial11.75
CD14+_Monocytes7.65
CD19+_BCells(neg._sel.)7.3
CD33+_Myeloid8.7
CD34+8.45
CD4+_Tcells7.05
CD56+_NKCells7.9
CD71+_EarlyErythroid6.8
CD8+_Tcells6.2
CardiacMyocytes11.2
Caudatenucleus7.25
Cerebellum6.35
CerebellumPeduncles8.45
CiliaryGanglion59.6
CingulateCortex7.95
Colorectaladenocarcinoma7.25
DorsalRootGanglion18.85
FetalThyroid7.4
Fetalbrain7
Fetalliver32.2
Fetallung12.65
GlobusPallidus5.5
Heart10.55
Hypothalamus14.55
Kidney6.25
Leukemia_chronicMyelogenousK-5626.55
Leukemia_promyelocytic-HL-606.3
Leukemialymphoblastic(MOLT-4)5.65
Liver10.25
Lung7.9
Lymphnode13.45
Lymphoma_burkitts(Daudi)9.2
Lymphoma_burkitts(Raji)10.65
MedullaOblongata6.75
OccipitalLobe6.75
OlfactoryBulb16.15
Ovary11.8
Pancreas6.25
PancreaticIslet8.95
ParietalLobe7.9
Pituitary32.2
Placenta7.05
Pons7.85
PrefrontalCortex8.85
Prostate8.45
Salivarygland24.05
SkeletalMuscle9.55
Skin31.2
SmoothMuscle8.45
Spinalcord105.05
SubthalamicNucleus8.5
SuperiorCervicalGanglion188.5
TemporalLobe7.2
Testis6.2
TestisGermCell22.5
TestisIntersitial9.55
TestisLeydigCell17.55
TestisSeminiferousTubule9.15
Thalamus7.7
Thymus5.6
Thyroid42.5
Tongue9.15
Tonsil7.4
Trachea62.45
TrigeminalGanglion32.45
Uterus51.7
UterusCorpus11.4
WholeBlood7.75
Wholebrain5.7
colon7.6
pineal_day8.94
pineal_night8.78
retina49.075
small_intestine7
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: CUST_7363_PI416261804
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala3.89 ± 0.79
Basal Forebrain3.46 ± 0.54
Basal Part of Pons3.28 ± 0.66
Cerebellar Cortex3.99 ± 0.39
Cerebellar Nuclei4.58 ± 0.56
Claustrum3.77 ± 0.69
Epithalamus6.26 ± 1.02
Frontal Lobe3.67 ± 0.83
Globus Pallidus5.11 ± 0.64
Hypothalamus4.07 ± 0.85
Insula3.64 ± 0.52
Limbic Lobe3.72 ± 0.71
Mesencephalon3.95 ± 0.71
Myelencephalon3.95 ± 0.78
Occipital Lobe4.1 ± 0.69
Parietal Lobe3.63 ± 0.8
Pontine Tegmentum3.89 ± 0.81
Striatum4.79 ± 0.78
Subthalamus3.61 ± 0.26
Temporal Lobe3.64 ± 0.76
Thalamus3.79 ± 0.42
White Matter4.39 ± 0.21
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Ecm2CBCerebellum14.3
19.15
Ecm2CTXCerebral cortex3.39
3.03
Ecm2HIPHippocampal region3.46
3.67
Ecm2HPFHippocampal formation4.4
4.17
Ecm2HYHypothalamus0.09
0.09
Ecm2LSXLateral septal complex2.92
3.9
Ecm2MBMidbrain0.82
1.3
Ecm2MYMedulla2.78
3.46
Ecm2OLFOlfactory bulb6.73
5.18
Ecm2PPons1.01
1.78
Ecm2PALPallidum0.65
0.78
Ecm2RHPRetrohippocampal region5.4
4.24
Ecm2sAMYStriatum-like amygdalar nuclei0.92
0.88
Ecm2STRStriatum1.06
1.13
Ecm2STRdStriatum dorsal region0.84
0.99
Ecm2STRvStriatum ventral region0.93
0.56
Ecm2THThalamus0.73
0.98
Peptide Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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