AutismKB 2.0

Annotation Detail for AGTR1


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Basic Information Top
Gene Symbol:AGTR1 ( AG2S,AGTR1A,AGTR1B,AT1,AT1B,AT1R,AT2R1,AT2R1A,AT2R1B,HAT1R )
Gene Full Name: angiotensin II receptor, type 1
Band: 3q24
Quick LinksEntrez ID:185; OMIM: 106165; Uniprot ID:AGTR1_HUMAN; ENSEMBL ID: ENSG00000144891; HGNC ID: 336
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body0 / 707610 
blastocyst0 / 623190 
fetus14 / 56401224
neonate0 / 310970 
infant0 / 236200 
juvenile1 / 5555617
adult60 / 193912130
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma0 / 174750 
breast (mammary gland) tumor9 / 9417895
cervical tumor0 / 343660 
chondrosarcoma1 / 8282312
colorectal tumor0 / 1142460 
esophageal tumor0 / 172900 
gastrointestinal tumor0 / 1193690 
germ cell tumor4 / 26384515
glioma0 / 1068830 
head and neck tumor0 / 1363020 
kidney tumor0 / 689590 
leukemia0 / 958420 
liver tumor5 / 9635951
lung tumor0 / 1031270 
lymphoma0 / 717550 
non-neoplasia0 / 972500 
normal86 / 336030725
ovarian tumor0 / 766820 
pancreatic tumor0 / 1046160 
primitive neuroectodermal tumor of the CNS0 / 1256800 
prostate cancer0 / 1026800 
retinoblastoma0 / 463560 
skin tumor0 / 1249490 
soft tissue/muscle tissue tumor0 / 1251910 
uterine tumor0 / 902570 
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland1 / 3319730
ascites0 / 400150 
bladder0 / 297570 
blood0 / 1234780 
bone0 / 716550 
bone marrow0 / 488010 
brain4 / 11009893
cervix0 / 481710 
connective tissue1 / 1492556
ear0 / 162120 
embryonic tissue0 / 2157220 
esophagus0 / 202090 
eye0 / 2110540 
heart3 / 8962633
intestine1 / 2344724
kidney7 / 21177733
larynx2 / 2414582
liver18 / 20774386
lung2 / 3369745
lymph0 / 442700 
lymph node0 / 916100 
mammary gland9 / 15327158
mouth0 / 670520 
muscle1 / 1077159
nerve1 / 1576863
ovary0 / 1020510 
pancreas0 / 2148120 
parathyroid0 / 205390 
pharynx0 / 413280 
pituitary gland0 / 165850 
placenta37 / 280825131
prostate0 / 1893450 
salivary gland0 / 201550 
skin2 / 2105749
spleen1 / 5395218
stomach0 / 966190 
testis2 / 3304426
thymus0 / 811310 
thyroid0 / 474730 
tonsil0 / 169990 
trachea0 / 524130 
umbilical cord0 / 136800 
uterus0 / 2328780 
vascular0 / 517800 
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 208016_s_at
Cell line Expression level Expression bar
721_B_lymphoblasts8.4
Adipocyte32.65
AdrenalCortex12.1
Adrenalgland32.05
Amygdala8.6
Appendix15.65
AtrioventricularNode9.25
BDCA4+_DentriticCells7.55
Bonemarrow9.4
BronchialEpithelialCells8.45
CD105+_Endothelial7.9
CD14+_Monocytes8.9
CD19+_BCells(neg._sel.)8.3
CD33+_Myeloid10
CD34+9.8
CD4+_Tcells7.9
CD56+_NKCells8.65
CD71+_EarlyErythroid8.15
CD8+_Tcells7
CardiacMyocytes12.55
Caudatenucleus9.55
Cerebellum10.25
CerebellumPeduncles10.65
CiliaryGanglion8.75
CingulateCortex10
Colorectaladenocarcinoma8.6
DorsalRootGanglion7.45
FetalThyroid9.75
Fetalbrain8.3
Fetalliver57.1
Fetallung6.9
GlobusPallidus8.5
Heart16.35
Hypothalamus9
Kidney9.2
Leukemia_chronicMyelogenousK-5627.45
Leukemia_promyelocytic-HL-607.6
Leukemialymphoblastic(MOLT-4)6.35
Liver18.2
Lung9.7
Lymphnode7.15
Lymphoma_burkitts(Daudi)11.7
Lymphoma_burkitts(Raji)13.15
MedullaOblongata8.2
OccipitalLobe7.55
OlfactoryBulb6.5
Ovary7.6
Pancreas7.4
PancreaticIslet9.5
ParietalLobe10.15
Pituitary10.25
Placenta233.35
Pons8.6
PrefrontalCortex10.3
Prostate9.9
Salivarygland7.85
SkeletalMuscle13.9
Skin8
SmoothMuscle9.55
Spinalcord9.25
SubthalamicNucleus8.2
SuperiorCervicalGanglion16
TemporalLobe8.35
Testis7.35
TestisGermCell7.05
TestisIntersitial7.4
TestisLeydigCell9.4
TestisSeminiferousTubule7.5
Thalamus9.05
Thymus6.55
Thyroid10.3
Tongue9.7
Tonsil8.6
Trachea7.25
TrigeminalGanglion12.3
Uterus6.9
UterusCorpus10
WholeBlood9.35
Wholebrain7
colon8.95
pineal_day9.9
pineal_night9.78
retina10.275
small_intestine8.7
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: A_23_P211835
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala2.23 ± 1.1
Basal Forebrain1.81 ± 0.2
Basal Part of Pons1.49 ± 0.37
Cerebellar Cortex1.86 ± 0.8
Cerebellar Nuclei2.13 ± 0.72
Claustrum2.76 ± 0.95
Epithalamus1.72 ± 0.57
Frontal Lobe1.7 ± 0.62
Globus Pallidus2.31 ± 0.5
Hypothalamus1.9 ± 0.7
Insula1.62 ± 0.61
Limbic Lobe1.82 ± 0.7
Mesencephalon2.41 ± 1.11
Myelencephalon1.92 ± 0.76
Occipital Lobe2 ± 0.76
Parietal Lobe1.81 ± 0.83
Pontine Tegmentum1.79 ± 0.53
Striatum1.96 ± 0.58
Subthalamus1.89 ± 0.62
Temporal Lobe1.82 ± 0.77
Thalamus1.77 ± 0.66
White Matter2.2 ± 0.18
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Agtr1aCBCerebellum100
100
Agtr1aCTXCerebral cortex100
100
Agtr1aHIPHippocampal region100
100
Agtr1aHPFHippocampal formation100
100
Agtr1aHYHypothalamus100
100
Agtr1aLSXLateral septal complex100
100
Agtr1aMBMidbrain100
99.17
Agtr1aMYMedulla100
100
Agtr1aOLFOlfactory bulb100
100
Agtr1aPPons100
100
Agtr1aPALPallidum100
100
Agtr1aRHPRetrohippocampal region100
100
Agtr1asAMYStriatum-like amygdalar nuclei100
100
Agtr1aSTRStriatum100
100
Agtr1aSTRdStriatum dorsal region100
100
Agtr1aSTRvStriatum ventral region100
100
Agtr1aTHThalamus100
100
Peptide Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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