AutismKB 2.0

Annotation Detail for EBF1


View Evidences View Variants View Annotations
Basic Information Top
Gene Symbol:EBF1 ( COE1,EBF,FLJ39389,FLJ41763,O/E-1,OLF1 )
Gene Full Name: early B-cell factor 1
Band: 5q33.3
Quick LinksEntrez ID:1879; OMIM: 164343; Uniprot ID:COE1_HUMAN; ENSEMBL ID: ENSG00000164330; HGNC ID: 3126
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body0 / 707610 
blastocyst0 / 623190 
fetus20 / 56401235
neonate0 / 310970 
infant2 / 2362084
juvenile0 / 555560 
adult32 / 193912116
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma0 / 174750 
breast (mammary gland) tumor2 / 9417821
cervical tumor0 / 343660 
chondrosarcoma1 / 8282312
colorectal tumor0 / 1142460 
esophageal tumor0 / 172900 
gastrointestinal tumor0 / 1193690 
germ cell tumor18 / 26384568
glioma0 / 1068830 
head and neck tumor3 / 13630222
kidney tumor1 / 6895914
leukemia5 / 9584252
liver tumor0 / 963590 
lung tumor0 / 1031270 
lymphoma1 / 7175513
non-neoplasia4 / 9725041
normal87 / 336030725
ovarian tumor0 / 766820 
pancreatic tumor0 / 1046160 
primitive neuroectodermal tumor of the CNS4 / 12568031
prostate cancer0 / 1026800 
retinoblastoma1 / 4635621
skin tumor0 / 1249490 
soft tissue/muscle tissue tumor3 / 12519123
uterine tumor0 / 902570 
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue1 / 1310676
adrenal gland0 / 331970 
ascites0 / 400150 
bladder0 / 297570 
blood0 / 1234780 
bone0 / 716550 
bone marrow1 / 4880120
brain15 / 110098913
cervix0 / 481710 
connective tissue5 / 14925533
ear2 / 16212123
embryonic tissue7 / 21572232
esophagus0 / 202090 
eye5 / 21105423
heart2 / 8962622
intestine1 / 2344724
kidney4 / 21177718
larynx3 / 24145124
liver1 / 2077434
lung1 / 3369742
lymph0 / 442700 
lymph node21 / 91610229
mammary gland6 / 15327139
mouth0 / 670520 
muscle2 / 10771518
nerve0 / 157680 
ovary0 / 1020510 
pancreas1 / 2148124
parathyroid0 / 205390 
pharynx1 / 4132824
pituitary gland0 / 165850 
placenta13 / 28082546
prostate4 / 18934521
salivary gland0 / 201550 
skin0 / 2105740 
spleen1 / 5395218
stomach0 / 966190 
testis6 / 33044218
thymus0 / 811310 
thyroid1 / 4747321
tonsil0 / 169990 
trachea2 / 5241338
umbilical cord0 / 136800 
uterus1 / 2328784
vascular1 / 5178019
Microarray in BioGPS Top
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: A_32_P197561
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala5.54 ± 0.34
Basal Forebrain6.28 ± 0.34
Basal Part of Pons5.24 ± 0.35
Cerebellar Cortex7.19 ± 0.5
Cerebellar Nuclei7.54 ± 0.37
Claustrum5.48 ± 0.49
Epithalamus6.56 ± 0.9
Frontal Lobe6.27 ± 0.65
Globus Pallidus6.93 ± 1.12
Hypothalamus6.41 ± 0.41
Insula6.26 ± 0.33
Limbic Lobe6 ± 0.63
Mesencephalon6.99 ± 0.69
Myelencephalon6.54 ± 0.78
Occipital Lobe6.5 ± 0.77
Parietal Lobe6.06 ± 0.63
Pontine Tegmentum6.69 ± 0.6
Striatum7.55 ± 1.32
Subthalamus6.58 ± 0.1
Temporal Lobe6.04 ± 0.44
Thalamus6.48 ± 0.54
White Matter6.41 ± 0.85
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Ebf1CBCerebellum25
30.81
Ebf1CTXCerebral cortex10.48
7.22
Ebf1HIPHippocampal region17.3
9.72
Ebf1HPFHippocampal formation13.09
7.07
Ebf1HYHypothalamus7.25
5.33
Ebf1LSXLateral septal complex11.78
6.37
Ebf1MBMidbrain10.02
8.65
Ebf1MYMedulla11.65
11.24
Ebf1OLFOlfactory bulb13.64
7.67
Ebf1PPons13.06
12.71
Ebf1PALPallidum5.94
4.59
Ebf1RHPRetrohippocampal region3.75
2.45
Ebf1sAMYStriatum-like amygdalar nuclei5.23
3.23
Ebf1STRStriatum5.22
3.12
Ebf1STRdStriatum dorsal region2.71
1.65
Ebf1STRvStriatum ventral region14.55
7.93
Ebf1THThalamus8.19
6.4
Peptide Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018