AutismKB 2.0

Annotation Detail for TYMP


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Basic Information Top
Gene Symbol:TYMP ( ECGF1,MNGIE,PDECGF,TP,hPD-ECGF )
Gene Full Name: thymidine phosphorylase
Band: 22q13.33
Quick LinksEntrez ID:1890; OMIM: 131222; Uniprot ID:TYPH_HUMAN; ENSEMBL ID: ENSG00000025708; HGNC ID: 3148
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body0 / 707610 
blastocyst0 / 623190 
fetus13 / 56401223
neonate1 / 3109732
infant0 / 236200 
juvenile2 / 5555635
adult225 / 1939121116
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma1 / 1747557
breast (mammary gland) tumor9 / 9417895
cervical tumor9 / 34366261
chondrosarcoma0 / 828230 
colorectal tumor4 / 11424635
esophageal tumor5 / 17290289
gastrointestinal tumor5 / 11936941
germ cell tumor11 / 26384541
glioma5 / 10688346
head and neck tumor11 / 13630280
kidney tumor0 / 689590 
leukemia4 / 9584241
liver tumor14 / 96359145
lung tumor35 / 103127339
lymphoma1 / 7175513
non-neoplasia12 / 97250123
normal228 / 336030767
ovarian tumor2 / 7668226
pancreatic tumor10 / 10461695
primitive neuroectodermal tumor of the CNS1 / 1256807
prostate cancer2 / 10268019
retinoblastoma0 / 463560 
skin tumor4 / 12494932
soft tissue/muscle tissue tumor1 / 1251917
uterine tumor9 / 9025799
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue2 / 13106152
adrenal gland1 / 3319730
ascites3 / 4001574
bladder2 / 2975767
blood32 / 123478259
bone1 / 7165513
bone marrow3 / 4880161
brain16 / 110098914
cervix9 / 48171186
connective tissue11 / 14925573
ear0 / 162120 
embryonic tissue0 / 2157220 
esophagus5 / 20209247
eye7 / 21105433
heart0 / 896260 
intestine15 / 23447263
kidney3 / 21177714
larynx6 / 24145248
liver25 / 207743120
lung60 / 336974178
lymph0 / 442700 
lymph node1 / 9161010
mammary gland15 / 15327197
mouth4 / 6705259
muscle1 / 1077159
nerve0 / 157680 
ovary5 / 10205148
pancreas21 / 21481297
parathyroid0 / 205390 
pharynx1 / 4132824
pituitary gland0 / 165850 
placenta83 / 280825295
prostate6 / 18934531
salivary gland0 / 201550 
skin8 / 21057437
spleen5 / 5395292
stomach2 / 9661920
testis1 / 3304423
thymus7 / 8113186
thyroid4 / 4747384
tonsil2 / 16999117
trachea1 / 5241319
umbilical cord0 / 136800 
uterus12 / 23287851
vascular0 / 517800 
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 204858_s_at
Cell line Expression level Expression bar
721_B_lymphoblasts5.6
Adipocyte4.3
AdrenalCortex4.3
Adrenalgland3.65
Amygdala4.6
Appendix4.25
AtrioventricularNode3.05
BDCA4+_DentriticCells67.95
Bonemarrow4.2
BronchialEpithelialCells15.75
CD105+_Endothelial4.35
CD14+_Monocytes500.6
CD19+_BCells(neg._sel.)4.65
CD33+_Myeloid297.65
CD34+6.05
CD4+_Tcells4.8
CD56+_NKCells25.15
CD71+_EarlyErythroid3.95
CD8+_Tcells4.25
CardiacMyocytes5.3
Caudatenucleus3.85
Cerebellum3.5
CerebellumPeduncles4.8
CiliaryGanglion2.9
CingulateCortex4.3
Colorectaladenocarcinoma4.35
DorsalRootGanglion3.05
FetalThyroid5.1
Fetalbrain4.35
Fetalliver3.7
Fetallung9.8
GlobusPallidus2.75
Heart33.9
Hypothalamus4.85
Kidney3.4
Leukemia_chronicMyelogenousK-5623.85
Leukemia_promyelocytic-HL-603.8
Leukemialymphoblastic(MOLT-4)3.55
Liver70.6
Lung87
Lymphnode22.85
Lymphoma_burkitts(Daudi)5.45
Lymphoma_burkitts(Raji)5.9
MedullaOblongata4.25
OccipitalLobe3.8
OlfactoryBulb3.35
Ovary2.8
Pancreas5.3
PancreaticIslet4.95
ParietalLobe4.45
Pituitary5
Placenta5.95
Pons4.05
PrefrontalCortex5.4
Prostate8.25
Salivarygland3.4
SkeletalMuscle4.6
Skin3.15
SmoothMuscle9.65
Spinalcord4.6
SubthalamicNucleus3.5
SuperiorCervicalGanglion4.4
TemporalLobe3.85
Testis3.8
TestisGermCell3.2
TestisIntersitial3.55
TestisLeydigCell4.2
TestisSeminiferousTubule3.7
Thalamus4.35
Thymus12.3
Thyroid6.35
Tongue4.1
Tonsil11.3
Trachea5.7
TrigeminalGanglion4.1
Uterus3.55
UterusCorpus3.75
WholeBlood103.5
Wholebrain3.75
colon4.3
pineal_day5.06
pineal_night5.22
retina5.25
small_intestine4.2
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: A_23_P91802
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala5.93 ± 0.43
Basal Forebrain5.75 ± 0.32
Basal Part of Pons5.98 ± 0.35
Cerebellar Cortex5.95 ± 0.36
Cerebellar Nuclei6.19 ± 0.32
Claustrum6.22 ± 0.32
Epithalamus7.44 ± 0.89
Frontal Lobe5.96 ± 0.48
Globus Pallidus6.61 ± 0.33
Hypothalamus5.92 ± 0.51
Insula5.91 ± 0.23
Limbic Lobe5.89 ± 0.39
Mesencephalon5.85 ± 0.46
Myelencephalon6.08 ± 0.52
Occipital Lobe5.56 ± 0.39
Parietal Lobe5.81 ± 0.49
Pontine Tegmentum5.91 ± 0.55
Striatum6.45 ± 0.56
Subthalamus5.97 ± 0.37
Temporal Lobe5.99 ± 0.44
Thalamus5.82 ± 0.28
White Matter5.71 ± 0.41
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Ecgf1CBCerebellum17.49
25.53
Ecgf1CTXCerebral cortex14.95
12.44
Ecgf1HIPHippocampal region12.09
15.12
Ecgf1HPFHippocampal formation11.36
12.81
Ecgf1HYHypothalamus1.85
1.59
Ecgf1LSXLateral septal complex4.58
4.24
Ecgf1MBMidbrain5.1
6.24
Ecgf1MYMedulla14.27
19.21
Ecgf1OLFOlfactory bulb7.89
6.51
Ecgf1PPons6.35
8.88
Ecgf1PALPallidum1.13
1.19
Ecgf1RHPRetrohippocampal region10.11
9.13
Ecgf1sAMYStriatum-like amygdalar nuclei0.72
0.82
Ecgf1STRStriatum1.33
1.23
Ecgf1STRdStriatum dorsal region0.85
0.86
Ecgf1STRvStriatum ventral region1.25
0.97
Ecgf1THThalamus6.94
8.24
Peptide Top
Peptide Name Peptide Lengh Peptide Start Peptide End Peptide Sequence Source
PAp00032575 19 375 393 AREQEELLAPADGTVELVR Peptide Atlas
TYPH_HUMAN_0 0 0 0 ALPLALVLHELGAGR PRIDE
TYPH_HUMAN_0 0 0 0 DVTATVDSLPLITASILSK PRIDE
TYPH_HUMAN_0 0 0 0 DVTATVDSLPLITASILSKK PRIDE
TYPH_HUMAN_202 19 202 220 DVTATVDSLPLITASILSK PRIDE
TYPH_HUMAN_253 12 253 264 TLVGVGASLGLR PRIDE
TYPH_HUMAN_303 26 303 328 DLVTTLGGALLWLSGHAGTQAQGAAR PRIDE
TYPH_HUMAN_329 13 329 341 VAAALDDGSALGR PRIDE
TYPH_HUMAN_329 16 329 344 VAAALDDGSALGRFER PRIDE
TYPH_HUMAN_345 13 345 357 MLAAQGVDPGLAR PRIDE
TYPH_HUMAN_374 19 374 392 AREQEELLAPADGTVELVR PRIDE
TYPH_HUMAN_393 15 393 407 ALPLALVLHELGAGR PRIDE
TYPH_HUMAN_453 11 453 463 ALQEALVLSDR PRIDE

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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