AutismKB 2.0

Annotation Detail for ECM1


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Basic Information Top
Gene Symbol:ECM1 ( - )
Gene Full Name: extracellular matrix protein 1
Band: 1q21.2
Quick LinksEntrez ID:1893; OMIM: 602201; Uniprot ID:ECM1_HUMAN; ENSEMBL ID: ENSG00000143369; HGNC ID: 3153
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body6 / 7076184
blastocyst1 / 6231916
fetus33 / 56401258
neonate5 / 31097160
infant0 / 236200 
juvenile5 / 5555689
adult365 / 1939121188
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma4 / 17475228
breast (mammary gland) tumor85 / 94178902
cervical tumor6 / 34366174
chondrosarcoma16 / 82823193
colorectal tumor2 / 11424617
esophageal tumor11 / 17290636
gastrointestinal tumor44 / 119369368
germ cell tumor45 / 263845170
glioma6 / 10688356
head and neck tumor36 / 136302264
kidney tumor0 / 689590 
leukemia2 / 9584220
liver tumor2 / 9635920
lung tumor2 / 10312719
lymphoma0 / 717550 
non-neoplasia42 / 97250431
normal351 / 3360307104
ovarian tumor1 / 7668213
pancreatic tumor4 / 10461638
primitive neuroectodermal tumor of the CNS4 / 12568031
prostate cancer0 / 1026800 
retinoblastoma0 / 463560 
skin tumor37 / 124949296
soft tissue/muscle tissue tumor1 / 1251917
uterine tumor2 / 9025722
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland7 / 33197210
ascites28 / 40015699
bladder4 / 29757134
blood2 / 12347816
bone10 / 71655139
bone marrow0 / 488010 
brain58 / 110098952
cervix12 / 48171249
connective tissue45 / 149255301
ear0 / 162120 
embryonic tissue7 / 21572232
esophagus17 / 20209841
eye12 / 21105456
heart21 / 89626234
intestine13 / 23447255
kidney9 / 21177742
larynx0 / 241450 
liver10 / 20774348
lung14 / 33697441
lymph0 / 442700 
lymph node1 / 9161010
mammary gland88 / 153271574
mouth4 / 6705259
muscle4 / 10771537
nerve1 / 1576863
ovary4 / 10205139
pancreas7 / 21481232
parathyroid0 / 205390 
pharynx5 / 41328120
pituitary gland1 / 1658560
placenta95 / 280825338
prostate10 / 18934552
salivary gland1 / 2015549
skin65 / 210574308
spleen11 / 53952203
stomach22 / 96619227
testis33 / 33044299
thymus2 / 8113124
thyroid30 / 47473631
tonsil0 / 169990 
trachea3 / 5241357
umbilical cord0 / 136800 
uterus33 / 232878141
vascular3 / 5178057
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 209365_s_at
Cell line Expression level Expression bar
721_B_lymphoblasts4.7
Adipocyte42.8
AdrenalCortex7.5
Adrenalgland6.35
Amygdala5.65
Appendix5.7
AtrioventricularNode4.5
BDCA4+_DentriticCells4.55
Bonemarrow5.4
BronchialEpithelialCells8.5
CD105+_Endothelial5.5
CD14+_Monocytes4.9
CD19+_BCells(neg._sel.)4.85
CD33+_Myeloid6.8
CD34+6.9
CD4+_Tcells5.55
CD56+_NKCells5.8
CD71+_EarlyErythroid5.15
CD8+_Tcells3.25
CardiacMyocytes16.3
Caudatenucleus4.95
Cerebellum4.5
CerebellumPeduncles6.25
CiliaryGanglion4.95
CingulateCortex6.3
Colorectaladenocarcinoma5
DorsalRootGanglion4.9
FetalThyroid5.45
Fetalbrain5.5
Fetalliver12
Fetallung5
GlobusPallidus5.55
Heart11.7
Hypothalamus5.9
Kidney4.7
Leukemia_chronicMyelogenousK-5627.5
Leukemia_promyelocytic-HL-604.6
Leukemialymphoblastic(MOLT-4)4.45
Liver29.5
Lung10.25
Lymphnode4.65
Lymphoma_burkitts(Daudi)6.8
Lymphoma_burkitts(Raji)7.9
MedullaOblongata5
OccipitalLobe4.7
OlfactoryBulb8.2
Ovary3.8
Pancreas5.9
PancreaticIslet6
ParietalLobe6.15
Pituitary6.55
Placenta52.75
Pons5.2
PrefrontalCortex7.35
Prostate6.55
Salivarygland4.4
SkeletalMuscle7.3
Skin5.2
SmoothMuscle41.65
Spinalcord5.9
SubthalamicNucleus6.7
SuperiorCervicalGanglion7.2
TemporalLobe5.05
Testis4.65
TestisGermCell7
TestisIntersitial4.9
TestisLeydigCell12.5
TestisSeminiferousTubule5.05
Thalamus5.6
Thymus3.95
Thyroid6.85
Tongue295.7
Tonsil28.8
Trachea4.8
TrigeminalGanglion7.3
Uterus11.6
UterusCorpus16.65
WholeBlood5.95
Wholebrain4.75
colon5.25
pineal_day7.66
pineal_night7.02
retina6.475
small_intestine4.95
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: CUST_17110_PI416261804
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala4.53 ± 0.88
Basal Forebrain4.29 ± 0.68
Basal Part of Pons5.2 ± 0.52
Cerebellar Cortex4.34 ± 0.54
Cerebellar Nuclei4.87 ± 0.48
Claustrum3.98 ± 0.78
Epithalamus4.03 ± 0.68
Frontal Lobe4.69 ± 0.63
Globus Pallidus3.83 ± 0.58
Hypothalamus4.07 ± 0.55
Insula4.6 ± 0.41
Limbic Lobe4.28 ± 0.61
Mesencephalon4.35 ± 0.69
Myelencephalon4.53 ± 0.74
Occipital Lobe4.81 ± 0.41
Parietal Lobe4.8 ± 0.61
Pontine Tegmentum4.35 ± 0.54
Striatum4.02 ± 0.79
Subthalamus5.53 ± 0.24
Temporal Lobe4.44 ± 0.56
Thalamus4.43 ± 0.53
White Matter3.18 ± 0.52
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Ecm1CBCerebellum13.21
16.75
Ecm1CTXCerebral cortex25.42
17.9
Ecm1HIPHippocampal region11.33
10.55
Ecm1HPFHippocampal formation14.22
12.06
Ecm1HYHypothalamus6.01
4.79
Ecm1LSXLateral septal complex1.81
1.28
Ecm1MBMidbrain7.58
7.2
Ecm1MYMedulla16.18
17.72
Ecm1OLFOlfactory bulb25.44
17.83
Ecm1PPons13.81
14.99
Ecm1PALPallidum8.81
7.36
Ecm1RHPRetrohippocampal region20.35
15
Ecm1sAMYStriatum-like amygdalar nuclei9.81
7
Ecm1STRStriatum10.53
7.2
Ecm1STRdStriatum dorsal region10.63
7.54
Ecm1STRvStriatum ventral region12.83
7.76
Ecm1THThalamus20.75
16.3
Peptide Top
Peptide Name Peptide Lengh Peptide Start Peptide End Peptide Sequence Source
ECM1_HUMAN_333 10 333 342 ELLALIQLER PRIDE
PAp00044002 12 116 127 ELPSLQHPNEQK Peptide Atlas

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018