AutismKB 2.0

Annotation Detail for NR0B1


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Basic Information Top
Gene Symbol:NR0B1 ( AHC,AHCH,AHX,DAX-1,DAX1,DSS,GTD,HHG,NROB1 )
Gene Full Name: nuclear receptor subfamily 0, group B, member 1
Band: Xp21.2
Quick LinksEntrez ID:190; OMIM: 300473; Uniprot ID:NR0B1_HUMAN; ENSEMBL ID: ENSG00000169297; HGNC ID: 7960
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body0 / 707610 
blastocyst0 / 623190 
fetus0 / 5640120 
neonate0 / 310970 
infant0 / 236200 
juvenile0 / 555560 
adult11 / 19391215
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor2 / 12794156
bladder carcinoma0 / 174750 
breast (mammary gland) tumor0 / 941780 
cervical tumor0 / 343660 
chondrosarcoma0 / 828230 
colorectal tumor0 / 1142460 
esophageal tumor0 / 172900 
gastrointestinal tumor0 / 1193690 
germ cell tumor6 / 26384522
glioma0 / 1068830 
head and neck tumor0 / 1363020 
kidney tumor0 / 689590 
leukemia0 / 958420 
liver tumor0 / 963590 
lung tumor4 / 10312738
lymphoma0 / 717550 
non-neoplasia0 / 972500 
normal17 / 33603075
ovarian tumor0 / 766820 
pancreatic tumor0 / 1046160 
primitive neuroectodermal tumor of the CNS0 / 1256800 
prostate cancer0 / 1026800 
retinoblastoma0 / 463560 
skin tumor0 / 1249490 
soft tissue/muscle tissue tumor0 / 1251910 
uterine tumor0 / 902570 
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland3 / 3319790
ascites0 / 400150 
bladder2 / 2975767
blood0 / 1234780 
bone0 / 716550 
bone marrow0 / 488010 
brain2 / 11009891
cervix0 / 481710 
connective tissue0 / 1492550 
ear0 / 162120 
embryonic tissue0 / 2157220 
esophagus0 / 202090 
eye0 / 2110540 
heart0 / 896260 
intestine0 / 2344720 
kidney0 / 2117770 
larynx0 / 241450 
liver0 / 2077430 
lung24 / 33697471
lymph0 / 442700 
lymph node0 / 916100 
mammary gland0 / 1532710 
mouth0 / 670520 
muscle0 / 1077150 
nerve0 / 157680 
ovary0 / 1020510 
pancreas9 / 21481241
parathyroid0 / 205390 
pharynx0 / 413280 
pituitary gland0 / 165850 
placenta0 / 2808250 
prostate0 / 1893450 
salivary gland0 / 201550 
skin0 / 2105740 
spleen0 / 539520 
stomach0 / 966190 
testis4 / 33044212
thymus0 / 811310 
thyroid0 / 474730 
tonsil0 / 169990 
trachea0 / 524130 
umbilical cord0 / 136800 
uterus0 / 2328780 
vascular0 / 517800 
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 206645_s_at
Cell line Expression level Expression bar
721_B_lymphoblasts6.8
Adipocyte5.95
AdrenalCortex12.45
Adrenalgland13.05
Amygdala6.2
Appendix6.65
AtrioventricularNode5.4
BDCA4+_DentriticCells6.1
Bonemarrow6.3
BronchialEpithelialCells5.85
CD105+_Endothelial5.95
CD14+_Monocytes6.25
CD19+_BCells(neg._sel.)6.1
CD33+_Myeloid7.35
CD34+7.45
CD4+_Tcells6.2
CD56+_NKCells6.65
CD71+_EarlyErythroid5.65
CD8+_Tcells5.35
CardiacMyocytes8.9
Caudatenucleus5.45
Cerebellum4.9
CerebellumPeduncles7.05
CiliaryGanglion4.65
CingulateCortex6.45
Colorectaladenocarcinoma6.05
DorsalRootGanglion5.15
FetalThyroid5.9
Fetalbrain5.9
Fetalliver5.25
Fetallung4.75
GlobusPallidus4.6
Heart9.45
Hypothalamus6.4
Kidney5.35
Leukemia_chronicMyelogenousK-5625.4
Leukemia_promyelocytic-HL-605.3
Leukemialymphoblastic(MOLT-4)4.75
Liver8.75
Lung6.5
Lymphnode5
Lymphoma_burkitts(Daudi)7.85
Lymphoma_burkitts(Raji)11.75
MedullaOblongata5.45
OccipitalLobe5.4
OlfactoryBulb4.7
Ovary4.2
Pancreas4.9
PancreaticIslet28.6
ParietalLobe6.6
Pituitary8.15
Placenta5.9
Pons5.85
PrefrontalCortex7.3
Prostate6.95
Salivarygland4.95
SkeletalMuscle9.1
Skin5.05
SmoothMuscle6.7
Spinalcord6.9
SubthalamicNucleus5.55
SuperiorCervicalGanglion7.95
TemporalLobe5.55
Testis58.05
TestisGermCell84.15
TestisIntersitial14.95
TestisLeydigCell8.85
TestisSeminiferousTubule20.4
Thalamus6.2
Thymus4.6
Thyroid7.35
Tongue6.45
Tonsil5.85
Trachea5
TrigeminalGanglion6.5
Uterus4.7
UterusCorpus5.7
WholeBlood6.5
Wholebrain4.95
colon6
pineal_day7.28
pineal_night7.16
retina7.2
small_intestine5.75
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: CUST_14976_PI416261804
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala3.73 ± 0.75
Basal Forebrain2.97 ± 0.56
Basal Part of Pons2.7 ± 0.4
Cerebellar Cortex2.81 ± 0.58
Cerebellar Nuclei3.19 ± 0.71
Claustrum3.33 ± 0.76
Epithalamus3.06 ± 0.86
Frontal Lobe3.3 ± 0.65
Globus Pallidus4.06 ± 0.46
Hypothalamus3.23 ± 0.52
Insula3.39 ± 0.74
Limbic Lobe3.22 ± 0.69
Mesencephalon3.65 ± 0.66
Myelencephalon3.27 ± 0.67
Occipital Lobe3.16 ± 0.48
Parietal Lobe3.12 ± 0.77
Pontine Tegmentum3.38 ± 0.71
Striatum3.74 ± 0.64
Subthalamus3.12 ± 0.86
Temporal Lobe3.34 ± 0.71
Thalamus3.57 ± 0.53
White Matter2.57 ± 0.87
Mouse Brain ISH
Peptide Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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