AutismKB 2.0

Annotation Detail for EGF


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Basic Information Top
Gene Symbol:EGF ( HOMG4,URG )
Gene Full Name: epidermal growth factor
Band: 4q25
Quick LinksEntrez ID:1950; OMIM: 131530; Uniprot ID:EGF_HUMAN; ENSEMBL ID: ENSG00000138798; HGNC ID: 3229
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body0 / 707610 
blastocyst0 / 623190 
fetus6 / 56401210
neonate0 / 310970 
infant0 / 236200 
juvenile0 / 555560 
adult49 / 193912125
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma0 / 174750 
breast (mammary gland) tumor1 / 9417810
cervical tumor0 / 343660 
chondrosarcoma0 / 828230 
colorectal tumor1 / 1142468
esophageal tumor0 / 172900 
gastrointestinal tumor0 / 1193690 
germ cell tumor2 / 2638457
glioma0 / 1068830 
head and neck tumor1 / 1363027
kidney tumor0 / 689590 
leukemia0 / 958420 
liver tumor0 / 963590 
lung tumor1 / 1031279
lymphoma0 / 717550 
non-neoplasia1 / 9725010
normal39 / 336030711
ovarian tumor0 / 766820 
pancreatic tumor0 / 1046160 
primitive neuroectodermal tumor of the CNS0 / 1256800 
prostate cancer0 / 1026800 
retinoblastoma0 / 463560 
skin tumor0 / 1249490 
soft tissue/muscle tissue tumor33 / 125191263
uterine tumor0 / 902570 
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland0 / 331970 
ascites0 / 400150 
bladder1 / 2975733
blood0 / 1234780 
bone0 / 716550 
bone marrow0 / 488010 
brain5 / 11009894
cervix0 / 481710 
connective tissue33 / 149255221
ear0 / 162120 
embryonic tissue0 / 2157220 
esophagus0 / 202090 
eye2 / 2110549
heart1 / 8962611
intestine2 / 2344728
kidney18 / 21177784
larynx0 / 241450 
liver0 / 2077430 
lung1 / 3369742
lymph0 / 442700 
lymph node0 / 916100 
mammary gland1 / 1532716
mouth1 / 6705214
muscle5 / 10771546
nerve0 / 157680 
ovary0 / 1020510 
pancreas4 / 21481218
parathyroid0 / 205390 
pharynx0 / 413280 
pituitary gland1 / 1658560
placenta1 / 2808253
prostate0 / 1893450 
salivary gland0 / 201550 
skin1 / 2105744
spleen0 / 539520 
stomach0 / 966190 
testis2 / 3304426
thymus0 / 811310 
thyroid0 / 474730 
tonsil0 / 169990 
trachea3 / 5241357
umbilical cord0 / 136800 
uterus0 / 2328780 
vascular0 / 517800 
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 206254_at
Cell line Expression level Expression bar
721_B_lymphoblasts6
Adipocyte5
AdrenalCortex5.75
Adrenalgland4.55
Amygdala5.2
Appendix7
AtrioventricularNode6.2
BDCA4+_DentriticCells5.45
Bonemarrow5.2
BronchialEpithelialCells4.9
CD105+_Endothelial5.1
CD14+_Monocytes5.8
CD19+_BCells(neg._sel.)5.35
CD33+_Myeloid6.5
CD34+6.3
CD4+_Tcells5.3
CD56+_NKCells5.75
CD71+_EarlyErythroid4.8
CD8+_Tcells4.7
CardiacMyocytes6.85
Caudatenucleus4.6
Cerebellum4.15
CerebellumPeduncles6.35
CiliaryGanglion9
CingulateCortex5.5
Colorectaladenocarcinoma5.05
DorsalRootGanglion4.5
FetalThyroid6.1
Fetalbrain4.95
Fetalliver4.45
Fetallung4.05
GlobusPallidus4.05
Heart6.85
Hypothalamus5.45
Kidney141.55
Leukemia_chronicMyelogenousK-5624.6
Leukemia_promyelocytic-HL-604.5
Leukemialymphoblastic(MOLT-4)4
Liver7.05
Lung5.55
Lymphnode4.25
Lymphoma_burkitts(Daudi)7.3
Lymphoma_burkitts(Raji)7.55
MedullaOblongata4.55
OccipitalLobe4.55
OlfactoryBulb4.05
Ovary3.75
Pancreas4.9
PancreaticIslet5.45
ParietalLobe5.55
Pituitary5.9
Placenta5.1
Pons4.95
PrefrontalCortex6.2
Prostate5.9
Salivarygland5.65
SkeletalMuscle11.8
Skin5.95
SmoothMuscle5.75
Spinalcord5.45
SubthalamicNucleus5.1
SuperiorCervicalGanglion9.5
TemporalLobe4.7
Testis4.3
TestisGermCell4.15
TestisIntersitial4.4
TestisLeydigCell5.5
TestisSeminiferousTubule4.35
Thalamus5.5
Thymus3.85
Thyroid6.3
Tongue7.8
Tonsil5.15
Trachea4.25
TrigeminalGanglion9.6
Uterus4.1
UterusCorpus6.2
WholeBlood6.1
Wholebrain4.15
colon5.1
pineal_day6.22
pineal_night6.16
retina6.425
small_intestine4.85
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: CUST_16_PI416408490
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala2.59 ± 1.03
Basal Forebrain2 ± 0.32
Basal Part of Pons1.76 ± 0.45
Cerebellar Cortex1.46 ± 0.7
Cerebellar Nuclei1.6 ± 0.6
Claustrum2.58 ± 0.82
Epithalamus2.43 ± 0.6
Frontal Lobe1.83 ± 0.8
Globus Pallidus2.09 ± 0.66
Hypothalamus1.6 ± 0.47
Insula1.67 ± 0.65
Limbic Lobe2.16 ± 0.82
Mesencephalon1.97 ± 0.72
Myelencephalon1.94 ± 0.74
Occipital Lobe1.47 ± 0.74
Parietal Lobe1.92 ± 0.91
Pontine Tegmentum1.86 ± 0.78
Striatum1.55 ± 0.84
Subthalamus1.73 ± 0.79
Temporal Lobe2 ± 0.84
Thalamus1.44 ± 0.7
White Matter1.81 ± 0.48
Mouse Brain ISH
Peptide Top
Peptide Name Peptide Lengh Peptide Start Peptide End Peptide Sequence Source
EGF_HUMAN_702 12 702 713 WAMPSVIRVNKR PRIDE
PAp00149810 14 283 296 INLHSSFVPLGELK Peptide Atlas

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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