AutismKB 2.0

Annotation Detail for AHR


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Basic Information Top
Gene Symbol:AHR ( bHLHe76 )
Gene Full Name: aryl hydrocarbon receptor
Band: 7p21.1
Quick LinksEntrez ID:196; OMIM: 600253; Uniprot ID:AHR_HUMAN; ENSEMBL ID: ENSG00000106546; HGNC ID: 348
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body0 / 707610 
blastocyst1 / 6231916
fetus25 / 56401244
neonate2 / 3109764
infant0 / 236200 
juvenile3 / 5555653
adult109 / 193912156
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma0 / 174750 
breast (mammary gland) tumor1 / 9417810
cervical tumor0 / 343660 
chondrosarcoma2 / 8282324
colorectal tumor9 / 11424678
esophageal tumor1 / 1729057
gastrointestinal tumor4 / 11936933
germ cell tumor0 / 2638450 
glioma9 / 10688384
head and neck tumor3 / 13630222
kidney tumor2 / 6895929
leukemia2 / 9584220
liver tumor5 / 9635951
lung tumor1 / 1031279
lymphoma2 / 7175527
non-neoplasia3 / 9725030
normal150 / 336030744
ovarian tumor0 / 766820 
pancreatic tumor0 / 1046160 
primitive neuroectodermal tumor of the CNS0 / 1256800 
prostate cancer2 / 10268019
retinoblastoma0 / 463560 
skin tumor6 / 12494948
soft tissue/muscle tissue tumor2 / 12519115
uterine tumor4 / 9025744
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue1 / 1310676
adrenal gland0 / 331970 
ascites1 / 4001524
bladder4 / 29757134
blood3 / 12347824
bone1 / 7165513
bone marrow4 / 4880181
brain15 / 110098913
cervix0 / 481710 
connective tissue5 / 14925533
ear1 / 1621261
embryonic tissue3 / 21572213
esophagus1 / 2020949
eye7 / 21105433
heart5 / 8962655
intestine13 / 23447255
kidney7 / 21177733
larynx0 / 241450 
liver11 / 20774352
lung15 / 33697444
lymph0 / 442700 
lymph node8 / 9161087
mammary gland14 / 15327191
mouth2 / 6705229
muscle4 / 10771537
nerve3 / 15768190
ovary0 / 1020510 
pancreas1 / 2148124
parathyroid3 / 20539146
pharynx0 / 413280 
pituitary gland0 / 165850 
placenta45 / 280825160
prostate6 / 18934531
salivary gland0 / 201550 
skin7 / 21057433
spleen0 / 539520 
stomach3 / 9661931
testis6 / 33044218
thymus1 / 8113112
thyroid1 / 4747321
tonsil0 / 169990 
trachea1 / 5241319
umbilical cord2 / 13680146
uterus5 / 23287821
vascular5 / 5178096
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 202820_at
Cell line Expression level Expression bar
721_B_lymphoblasts15.2
Adipocyte17
AdrenalCortex35.25
Adrenalgland18.4
Amygdala15.9
Appendix48.3
AtrioventricularNode28.95
BDCA4+_DentriticCells32.2
Bonemarrow16.4
BronchialEpithelialCells20.9
CD105+_Endothelial22.4
CD14+_Monocytes170.85
CD19+_BCells(neg._sel.)17.1
CD33+_Myeloid250.5
CD34+45
CD4+_Tcells21.55
CD56+_NKCells16.55
CD71+_EarlyErythroid12.5
CD8+_Tcells14.55
CardiacMyocytes79.85
Caudatenucleus13.05
Cerebellum11.75
CerebellumPeduncles26.75
CiliaryGanglion32.75
CingulateCortex16.1
Colorectaladenocarcinoma16.15
DorsalRootGanglion30.8
FetalThyroid31.6
Fetalbrain14.2
Fetalliver15.5
Fetallung66.55
GlobusPallidus14.2
Heart43.5
Hypothalamus14.55
Kidney13.45
Leukemia_chronicMyelogenousK-56298.55
Leukemia_promyelocytic-HL-6012.4
Leukemialymphoblastic(MOLT-4)10.2
Liver37.8
Lung56.7
Lymphnode44.45
Lymphoma_burkitts(Daudi)18.85
Lymphoma_burkitts(Raji)20.15
MedullaOblongata12.75
OccipitalLobe13.75
OlfactoryBulb112.85
Ovary15.1
Pancreas21.45
PancreaticIslet26.8
ParietalLobe23.4
Pituitary19.8
Placenta448.9
Pons16.55
PrefrontalCortex17.2
Prostate50
Salivarygland58.55
SkeletalMuscle26.5
Skin36.3
SmoothMuscle80.8
Spinalcord18.8
SubthalamicNucleus18.65
SuperiorCervicalGanglion27.25
TemporalLobe18.05
Testis12.25
TestisGermCell16.1
TestisIntersitial19.4
TestisLeydigCell16.95
TestisSeminiferousTubule13.05
Thalamus15.65
Thymus13.9
Thyroid52.5
Tongue33.4
Tonsil27.3
Trachea26.9
TrigeminalGanglion39.6
Uterus60.6
UterusCorpus17.35
WholeBlood32.15
Wholebrain10.85
colon175.8
pineal_day18.26
pineal_night26.42
retina35.95
small_intestine235
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: CUST_16863_PI416261804
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala4.38 ± 0.58
Basal Forebrain4.32 ± 0.35
Basal Part of Pons4.56 ± 0.56
Cerebellar Cortex4.12 ± 0.46
Cerebellar Nuclei4.77 ± 0.44
Claustrum4.64 ± 0.85
Epithalamus4.46 ± 0.73
Frontal Lobe4.59 ± 0.61
Globus Pallidus4.77 ± 0.42
Hypothalamus4.2 ± 0.65
Insula4.78 ± 0.28
Limbic Lobe4.56 ± 0.57
Mesencephalon4.6 ± 0.64
Myelencephalon4.59 ± 0.57
Occipital Lobe4.37 ± 0.61
Parietal Lobe4.62 ± 0.49
Pontine Tegmentum4.63 ± 0.61
Striatum4.64 ± 0.56
Subthalamus4.66 ± 0.47
Temporal Lobe4.77 ± 0.47
Thalamus4.63 ± 0.49
White Matter6.45 ± 0.38
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
AhrHYHypothalamus0.32
0.49
Peptide Top
Peptide Name Peptide Lengh Peptide Start Peptide End Peptide Sequence Source
AHR_HUMAN_1 13 1 13 MNSSSANITYASR PRIDE

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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