AutismKB 2.0

Annotation Detail for EIF4G2


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Basic Information Top
Gene Symbol:EIF4G2 ( AAG1,DAP5,FLJ41344,NAT1,P97 )
Gene Full Name: eukaryotic translation initiation factor 4 gamma, 2
Band: 11p15.4
Quick LinksEntrez ID:1982; OMIM: 602325; Uniprot ID:IF4G2_HUMAN; ENSEMBL ID: ENSG00000110321; HGNC ID: 3297
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body127 / 707611794
blastocyst68 / 623191091
fetus570 / 5640121010
neonate18 / 31097578
infant13 / 23620550
juvenile64 / 555561151
adult1054 / 1939121543
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor5 / 12794390
bladder carcinoma7 / 17475400
breast (mammary gland) tumor118 / 941781252
cervical tumor19 / 34366552
chondrosarcoma26 / 82823313
colorectal tumor56 / 114246490
esophageal tumor41 / 172902371
gastrointestinal tumor60 / 119369502
germ cell tumor322 / 2638451220
glioma60 / 106883561
head and neck tumor157 / 1363021151
kidney tumor53 / 68959768
leukemia59 / 95842615
liver tumor86 / 96359892
lung tumor33 / 103127319
lymphoma21 / 71755292
non-neoplasia63 / 97250647
normal2365 / 3360307703
ovarian tumor36 / 76682469
pancreatic tumor50 / 104616477
primitive neuroectodermal tumor of the CNS50 / 125680397
prostate cancer49 / 102680477
retinoblastoma23 / 46356496
skin tumor82 / 124949656
soft tissue/muscle tissue tumor71 / 125191567
uterine tumor63 / 90257698
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue8 / 13106610
adrenal gland13 / 33197391
ascites16 / 40015399
bladder34 / 297571142
blood50 / 123478404
bone27 / 71655376
bone marrow41 / 48801840
brain1375 / 11009891248
cervix19 / 48171394
connective tissue63 / 149255422
ear26 / 162121603
embryonic tissue270 / 2157221251
esophagus41 / 202092028
eye73 / 211054345
heart33 / 89626368
intestine99 / 234472422
kidney100 / 211777472
larynx11 / 24145455
liver118 / 207743568
lung140 / 336974415
lymph11 / 44270248
lymph node54 / 91610589
mammary gland154 / 1532711004
mouth115 / 670521715
muscle56 / 107715519
nerve12 / 15768761
ovary43 / 102051421
pancreas104 / 214812484
parathyroid13 / 20539632
pharynx6 / 41328145
pituitary gland6 / 16585361
placenta182 / 280825648
prostate62 / 189345327
salivary gland6 / 20155297
skin121 / 210574574
spleen27 / 53952500
stomach51 / 96619527
testis496 / 3304421501
thymus86 / 811311060
thyroid43 / 47473905
tonsil1 / 1699958
trachea245 / 524134674
umbilical cord2 / 13680146
uterus295 / 2328781266
vascular183 / 517803534
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 200004_at
Cell line Expression level Expression bar
721_B_lymphoblasts2071.8
Adipocyte1378.2
AdrenalCortex756.9
Adrenalgland357.15
Amygdala1276.2
Appendix432.2
AtrioventricularNode193.05
BDCA4+_DentriticCells1947.85
Bonemarrow424.7
BronchialEpithelialCells1940.35
CD105+_Endothelial1300.4
CD14+_Monocytes1609.45
CD19+_BCells(neg._sel.)1541.1
CD33+_Myeloid2219.85
CD34+1825.05
CD4+_Tcells1505.05
CD56+_NKCells1690.2
CD71+_EarlyErythroid917.4
CD8+_Tcells1246.4
CardiacMyocytes1571.65
Caudatenucleus583.1
Cerebellum455
CerebellumPeduncles917.75
CiliaryGanglion214.65
CingulateCortex799
Colorectaladenocarcinoma2118.95
DorsalRootGanglion327.9
FetalThyroid1096.8
Fetalbrain2704.5
Fetalliver786.45
Fetallung1225.2
GlobusPallidus414.4
Heart134.2
Hypothalamus1866.65
Kidney327.5
Leukemia_chronicMyelogenousK-562885.65
Leukemia_promyelocytic-HL-60777.45
Leukemialymphoblastic(MOLT-4)1202.7
Liver112.35
Lung481.2
Lymphnode1073.35
Lymphoma_burkitts(Daudi)1180.75
Lymphoma_burkitts(Raji)451.75
MedullaOblongata848.05
OccipitalLobe1266.4
OlfactoryBulb869.05
Ovary344.65
Pancreas711.8
PancreaticIslet1422.4
ParietalLobe997.3
Pituitary1576.75
Placenta2140.8
Pons514.2
PrefrontalCortex1913.6
Prostate986.3
Salivarygland723.3
SkeletalMuscle275.35
Skin334.6
SmoothMuscle2100.05
Spinalcord1214.25
SubthalamicNucleus601.05
SuperiorCervicalGanglion167.25
TemporalLobe584.95
Testis501.7
TestisGermCell1794.15
TestisIntersitial1017.45
TestisLeydigCell941.45
TestisSeminiferousTubule813.8
Thalamus1058.5
Thymus1069
Thyroid2142.35
Tongue679.65
Tonsil1292.15
Trachea750.25
TrigeminalGanglion236.05
Uterus1243.5
UterusCorpus977.9
WholeBlood2052.75
Wholebrain847.25
colon1350.75
pineal_day1861.08
pineal_night1895.02
retina1445.775
small_intestine964.9
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: A_23_P104892
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala10.84 ± 0.22
Basal Forebrain10.99 ± 0.16
Basal Part of Pons11.04 ± 0.14
Cerebellar Cortex10.98 ± 0.16
Cerebellar Nuclei11.15 ± 0.21
Claustrum10.63 ± 0.29
Epithalamus11.2 ± 0.14
Frontal Lobe11.1 ± 0.23
Globus Pallidus11.02 ± 0.24
Hypothalamus11.3 ± 0.16
Insula10.95 ± 0.19
Limbic Lobe10.92 ± 0.31
Mesencephalon11.15 ± 0.29
Myelencephalon11.01 ± 0.26
Occipital Lobe11.05 ± 0.31
Parietal Lobe11.06 ± 0.27
Pontine Tegmentum11.03 ± 0.22
Striatum10.76 ± 0.18
Subthalamus11.27 ± 0.16
Temporal Lobe11.08 ± 0.23
Thalamus11.11 ± 0.16
White Matter10.79 ± 0.12
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Eif4g2CBCerebellum78.68
100
Eif4g2CTXCerebral cortex100
100
Eif4g2HIPHippocampal region100
100
Eif4g2HPFHippocampal formation100
100
Eif4g2HYHypothalamus100
100
Eif4g2LSXLateral septal complex100
100
Eif4g2MBMidbrain100
100
Eif4g2MYMedulla100
100
Eif4g2OLFOlfactory bulb100
100
Eif4g2PPons100
100
Eif4g2PALPallidum100
100
Eif4g2RHPRetrohippocampal region100
100
Eif4g2sAMYStriatum-like amygdalar nuclei100
100
Eif4g2STRStriatum100
100
Eif4g2STRdStriatum dorsal region100
100
Eif4g2STRvStriatum ventral region100
100
Eif4g2THThalamus100
100
Peptide Top
Peptide Name Peptide Lengh Peptide Start Peptide End Peptide Sequence Source
PAp00026740 21 88 108 LTPEKFDKLCLELLNVGVESK Peptide Atlas

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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