AutismKB 2.0

Annotation Detail for CRTC2


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Basic Information Top
Gene Symbol:CRTC2 ( TORC2 )
Gene Full Name: CREB regulated transcription coactivator 2
Band: 1q21.3
Quick LinksEntrez ID:200186; OMIM: 608972; Uniprot ID:CRTC2_HUMAN; ENSEMBL ID: ENSG00000160741; HGNC ID: 27301
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body2 / 7076128
blastocyst2 / 6231932
fetus5 / 5640128
neonate0 / 310970 
infant0 / 236200 
juvenile2 / 5555635
adult87 / 193912144
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma2 / 17475114
breast (mammary gland) tumor2 / 9417821
cervical tumor2 / 3436658
chondrosarcoma9 / 82823108
colorectal tumor6 / 11424652
esophageal tumor0 / 172900 
gastrointestinal tumor3 / 11936925
germ cell tumor2 / 2638457
glioma6 / 10688356
head and neck tumor3 / 13630222
kidney tumor1 / 6895914
leukemia5 / 9584252
liver tumor2 / 9635920
lung tumor5 / 10312748
lymphoma5 / 7175569
non-neoplasia4 / 9725041
normal80 / 336030723
ovarian tumor4 / 7668252
pancreatic tumor4 / 10461638
primitive neuroectodermal tumor of the CNS5 / 12568039
prostate cancer2 / 10268019
retinoblastoma0 / 463560 
skin tumor4 / 12494932
soft tissue/muscle tissue tumor1 / 1251917
uterine tumor4 / 9025744
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland0 / 331970 
ascites2 / 4001549
bladder1 / 2975733
blood5 / 12347840
bone8 / 71655111
bone marrow1 / 4880120
brain22 / 110098919
cervix4 / 4817183
connective tissue3 / 14925520
ear0 / 162120 
embryonic tissue8 / 21572237
esophagus0 / 202090 
eye4 / 21105418
heart0 / 896260 
intestine9 / 23447238
kidney4 / 21177718
larynx1 / 2414541
liver3 / 20774314
lung8 / 33697423
lymph2 / 4427045
lymph node3 / 9161032
mammary gland9 / 15327158
mouth1 / 6705214
muscle1 / 1077159
nerve2 / 15768126
ovary2 / 10205119
pancreas10 / 21481246
parathyroid1 / 2053948
pharynx0 / 413280 
pituitary gland0 / 165850 
placenta4 / 28082514
prostate2 / 18934510
salivary gland0 / 201550 
skin6 / 21057428
spleen0 / 539520 
stomach2 / 9661920
testis9 / 33044227
thymus1 / 8113112
thyroid9 / 47473189
tonsil1 / 1699958
trachea0 / 524130 
umbilical cord0 / 136800 
uterus6 / 23287825
vascular1 / 5178019
Microarray in BioGPS Top
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: A_23_P12178
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala4.4 ± 0.51
Basal Forebrain4.6 ± 0.27
Basal Part of Pons4.79 ± 0.38
Cerebellar Cortex5.13 ± 0.29
Cerebellar Nuclei4.84 ± 0.45
Claustrum4.33 ± 0.98
Epithalamus4.71 ± 0.54
Frontal Lobe4.65 ± 0.44
Globus Pallidus4.74 ± 0.39
Hypothalamus4.31 ± 0.61
Insula4.46 ± 0.25
Limbic Lobe4.63 ± 0.45
Mesencephalon4.63 ± 0.52
Myelencephalon4.73 ± 0.47
Occipital Lobe4.95 ± 0.56
Parietal Lobe4.64 ± 0.43
Pontine Tegmentum4.67 ± 0.48
Striatum4.64 ± 0.47
Subthalamus4.17 ± 0.12
Temporal Lobe4.71 ± 0.39
Thalamus4.77 ± 0.41
White Matter5.61 ± 0.2
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Crtc2CBCerebellum43.18
87.41
Crtc2CTXCerebral cortex27.45
21.37
Crtc2HIPHippocampal region38.41
53.51
Crtc2HPFHippocampal formation37.06
44.2
Crtc2HYHypothalamus3.87
3.37
Crtc2LSXLateral septal complex1.22
0.93
Crtc2MBMidbrain1.33
1.68
Crtc2MYMedulla6.31
10.47
Crtc2OLFOlfactory bulb39.29
42.85
Crtc2PPons5.44
7.21
Crtc2PALPallidum11.66
10.34
Crtc2RHPRetrohippocampal region34.18
28.8
Crtc2sAMYStriatum-like amygdalar nuclei81.17
68.2
Crtc2STRStriatum27.28
21.92
Crtc2STRdStriatum dorsal region24.36
17.99
Crtc2STRvStriatum ventral region22.49
20.2
Crtc2THThalamus6.19
6.33
Peptide Top
Peptide Name Peptide Lengh Peptide Start Peptide End Peptide Sequence Source
PAp00011494 24 504 527 SLQQPGLPSQSCSVQSSGGQPPGR Peptide Atlas

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018