AutismKB 2.0

Annotation Detail for ELK1


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Basic Information Top
Gene Symbol:ELK1 ( - )
Gene Full Name: ELK1, member of ETS oncogene family
Band: Xp11.23
Quick LinksEntrez ID:2002; OMIM: 311040; Uniprot ID:ELK1_HUMAN; ENSEMBL ID: ENSG00000126767; HGNC ID: 3321
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body0 / 707610 
blastocyst2 / 6231932
fetus9 / 56401215
neonate0 / 310970 
infant0 / 236200 
juvenile1 / 5555617
adult34 / 193912117
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma0 / 174750 
breast (mammary gland) tumor1 / 9417810
cervical tumor1 / 3436629
chondrosarcoma4 / 8282348
colorectal tumor1 / 1142468
esophageal tumor0 / 172900 
gastrointestinal tumor4 / 11936933
germ cell tumor7 / 26384526
glioma2 / 10688318
head and neck tumor2 / 13630214
kidney tumor0 / 689590 
leukemia0 / 958420 
liver tumor1 / 9635910
lung tumor1 / 1031279
lymphoma8 / 71755111
non-neoplasia1 / 9725010
normal48 / 336030714
ovarian tumor1 / 7668213
pancreatic tumor2 / 10461619
primitive neuroectodermal tumor of the CNS5 / 12568039
prostate cancer3 / 10268029
retinoblastoma2 / 4635643
skin tumor1 / 1249498
soft tissue/muscle tissue tumor8 / 12519163
uterine tumor0 / 902570 
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland0 / 331970 
ascites0 / 400150 
bladder1 / 2975733
blood1 / 1234788
bone1 / 7165513
bone marrow0 / 488010 
brain19 / 110098917
cervix3 / 4817162
connective tissue1 / 1492556
ear0 / 162120 
embryonic tissue4 / 21572218
esophagus0 / 202090 
eye10 / 21105447
heart0 / 896260 
intestine3 / 23447212
kidney0 / 2117770 
larynx0 / 241450 
liver2 / 2077439
lung11 / 33697432
lymph1 / 4427022
lymph node1 / 9161010
mammary gland1 / 1532716
mouth0 / 670520 
muscle0 / 1077150 
nerve0 / 157680 
ovary2 / 10205119
pancreas2 / 2148129
parathyroid0 / 205390 
pharynx0 / 413280 
pituitary gland0 / 165850 
placenta0 / 2808250 
prostate3 / 18934515
salivary gland0 / 201550 
skin2 / 2105749
spleen0 / 539520 
stomach3 / 9661931
testis7 / 33044221
thymus2 / 8113124
thyroid2 / 4747342
tonsil0 / 169990 
trachea0 / 524130 
umbilical cord0 / 136800 
uterus9 / 23287838
vascular0 / 517800 
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 210376_x_at
Cell line Expression level Expression bar
721_B_lymphoblasts9
Adipocyte4.3
AdrenalCortex4.55
Adrenalgland7.5
Amygdala5.95
Appendix4.35
AtrioventricularNode3.8
BDCA4+_DentriticCells4.95
Bonemarrow4.25
BronchialEpithelialCells4.25
CD105+_Endothelial4.4
CD14+_Monocytes4.6
CD19+_BCells(neg._sel.)4.45
CD33+_Myeloid5.65
CD34+5.5
CD4+_Tcells4.75
CD56+_NKCells4.95
CD71+_EarlyErythroid4.1
CD8+_Tcells4.3
CardiacMyocytes5.2
Caudatenucleus6.2
Cerebellum6.1
CerebellumPeduncles6.45
CiliaryGanglion4.3
CingulateCortex4.45
Colorectaladenocarcinoma5.85
DorsalRootGanglion3.3
FetalThyroid4.3
Fetalbrain4.4
Fetalliver3.8
Fetallung3.65
GlobusPallidus3.2
Heart6.2
Hypothalamus4.75
Kidney3.55
Leukemia_chronicMyelogenousK-5624
Leukemia_promyelocytic-HL-603.85
Leukemialymphoblastic(MOLT-4)3.5
Liver5.75
Lung4.8
Lymphnode3.75
Lymphoma_burkitts(Daudi)5.5
Lymphoma_burkitts(Raji)6
MedullaOblongata4.5
OccipitalLobe4
OlfactoryBulb3.45
Ovary2.9
Pancreas3.5
PancreaticIslet4.7
ParietalLobe4.55
Pituitary5.1
Placenta7.4
Pons4.4
PrefrontalCortex9.6
Prostate5.15
Salivarygland3.5
SkeletalMuscle5
Skin3.9
SmoothMuscle6
Spinalcord4.7
SubthalamicNucleus5.4
SuperiorCervicalGanglion4.9
TemporalLobe4.5
Testis3.75
TestisGermCell4.85
TestisIntersitial3.8
TestisLeydigCell4.3
TestisSeminiferousTubule3.75
Thalamus4.45
Thymus3.45
Thyroid5.45
Tongue4.25
Tonsil4.25
Trachea3.7
TrigeminalGanglion4.5
Uterus3.45
UterusCorpus7.8
WholeBlood4.8
Wholebrain3.8
colon4.25
pineal_day6
pineal_night5.98
retina5.275
small_intestine4.05
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: CUST_15194_PI416261804
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala4.71 ± 0.72
Basal Forebrain3.45 ± 0.25
Basal Part of Pons3.46 ± 0.56
Cerebellar Cortex3.32 ± 0.78
Cerebellar Nuclei2.94 ± 0.34
Claustrum4.51 ± 0.81
Epithalamus2.83 ± 0.6
Frontal Lobe3.19 ± 0.81
Globus Pallidus2.28 ± 0.76
Hypothalamus2.88 ± 0.63
Insula3.71 ± 0.73
Limbic Lobe4.05 ± 0.86
Mesencephalon3.3 ± 0.72
Myelencephalon3.38 ± 0.64
Occipital Lobe3.38 ± 0.93
Parietal Lobe3.55 ± 0.85
Pontine Tegmentum3.43 ± 0.83
Striatum3.72 ± 0.62
Subthalamus3.09 ± 0.45
Temporal Lobe3.72 ± 0.84
Thalamus2.82 ± 0.63
White Matter2.08 ± 0.53
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Elk1CBCerebellum23.93
13.25
Elk1CTXCerebral cortex21.49
10.6
Elk1HIPHippocampal region50.69
59.57
Elk1HPFHippocampal formation47.63
45.18
Elk1HYHypothalamus8.24
4.36
Elk1LSXLateral septal complex3.05
1.92
Elk1MBMidbrain7.84
4.33
Elk1MYMedulla16.37
10.04
Elk1OLFOlfactory bulb22.1
13.27
Elk1PPons11.71
6.83
Elk1PALPallidum4.6
2.57
Elk1RHPRetrohippocampal region42.29
22.17
Elk1sAMYStriatum-like amygdalar nuclei14.53
7.76
Elk1STRStriatum8.38
4.16
Elk1STRdStriatum dorsal region8.9
4.32
Elk1STRvStriatum ventral region6.63
3.28
Elk1THThalamus6.66
4.6
Peptide Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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