Annotation Detail for MARK2
Basic Information Top
| Gene Symbol: | MARK2 ( EMK-1,EMK1,MGC99619,PAR-1,Par1b ) |
|---|---|
| Gene Full Name: | MAP/microtubule affinity-regulating kinase 2 |
| Band: | 11q13.1 |
| Quick Links | Entrez ID:2011; OMIM: 600526; Uniprot ID:MARK2_HUMAN; ENSEMBL ID: ENSG00000072518; HGNC ID: 3332 |
| Relate to Another Database: | SFARIGene; denovo-db |
- Unigene ID: Hs.567261
| Pool Name | Gene EST/Total EST in pool | Transcripts per million(TPM) | Bar based on TPM |
|---|---|---|---|
 | |||
| embryoid body | 2 / 70761 | 28 |  |
| blastocyst | 3 / 62319 | 48 | |
| fetus | 10 / 564012 | 17 | |
| neonate | 0 / 31097 | 0 | |
| infant | 0 / 23620 | 0 | |
| juvenile | 0 / 55556 | 0 | |
| adult | 105 / 1939121 | 54 |  |
| Pool Name | Gene EST/Total EST in pool | Transcripts per million(TPM) | Bar based on TPM |
|---|---|---|---|
| |||
| adrenal tumor | 1 / 12794 | 78 | |
| bladder carcinoma | 1 / 17475 | 57 | |
| breast (mammary gland) tumor | 8 / 94178 | 84 | |
| cervical tumor | 3 / 34366 | 87 | |
| chondrosarcoma | 2 / 82823 | 24 | |
| colorectal tumor | 10 / 114246 | 87 | |
| esophageal tumor | 0 / 17290 | 0 | |
| gastrointestinal tumor | 3 / 119369 | 25 | |
| germ cell tumor | 10 / 263845 | 37 | |
| glioma | 2 / 106883 | 18 | |
| head and neck tumor | 22 / 136302 | 161 | |
| kidney tumor | 5 / 68959 | 72 | |
| leukemia | 6 / 95842 | 62 | |
| liver tumor | 2 / 96359 | 20 | |
| lung tumor | 6 / 103127 | 58 | |
| lymphoma | 9 / 71755 | 125 | |
| non-neoplasia | 1 / 97250 | 10 |  |
| normal | 99 / 3360307 | 29 | |
| ovarian tumor | 3 / 76682 | 39 | |
| pancreatic tumor | 6 / 104616 | 57 | |
| primitive neuroectodermal tumor of the CNS | 3 / 125680 | 23 | |
| prostate cancer | 2 / 102680 | 19 | |
| retinoblastoma | 0 / 46356 | 0 | |
| skin tumor | 6 / 124949 | 48 | |
| soft tissue/muscle tissue tumor | 7 / 125191 | 55 | |
| uterine tumor | 9 / 90257 | 99 | |
| Pool Name | Gene EST/Total EST in pool | Transcripts per million(TPM) | Bar based on TPM |
|---|---|---|---|
| |||
| adipose tissue | 0 / 13106 | 0 | |
| adrenal gland | 1 / 33197 | 30 | |
| ascites | 0 / 40015 | 0 | |
| bladder | 2 / 29757 | 67 | |
| blood | 2 / 123478 | 16 | |
| bone | 6 / 71655 | 83 | |
| bone marrow | 0 / 48801 | 0 | |
| brain | 28 / 1100989 | 25 | |
| cervix | 6 / 48171 | 124 | |
| connective tissue | 2 / 149255 | 13 | |
| ear | 0 / 16212 | 0 | |
| embryonic tissue | 8 / 215722 | 37 | |
| esophagus | 0 / 20209 | 0 | |
| eye | 6 / 211054 | 28 | |
| heart | 1 / 89626 | 11 | |
| intestine | 19 / 234472 | 81 | |
| kidney | 6 / 211777 | 28 | |
| larynx | 4 / 24145 | 165 | |
| liver | 3 / 207743 | 14 | |
| lung | 12 / 336974 | 35 | |
| lymph | 7 / 44270 | 158 | |
| lymph node | 1 / 91610 | 10 | |
| mammary gland | 10 / 153271 | 65 | |
| mouth | 5 / 67052 | 74 | |
| muscle | 4 / 107715 | 37 | |
| nerve | 1 / 15768 | 63 | |
| ovary | 3 / 102051 | 29 | |
| pancreas | 13 / 214812 | 60 | |
| parathyroid | 0 / 20539 | 0 | |
| pharynx | 12 / 41328 | 290 |  |
| pituitary gland | 1 / 16585 | 60 | |
| placenta | 16 / 280825 | 56 | |
| prostate | 8 / 189345 | 42 | |
| salivary gland | 2 / 20155 | 99 | |
| skin | 6 / 210574 | 28 | |
| spleen | 0 / 53952 | 0 | |
| stomach | 2 / 96619 | 20 | |
| testis | 3 / 330442 | 9 | |
| thymus | 1 / 81131 | 12 | |
| thyroid | 1 / 47473 | 21 | |
| tonsil | 0 / 16999 | 0 | |
| trachea | 0 / 52413 | 0 | |
| umbilical cord | 0 / 13680 | 0 | |
| uterus | 13 / 232878 | 55 | |
| vascular | 1 / 51780 | 19 | |
- Microarray Platform: GeneAtlas U133A, gcrma
- Affymatrix Probe ID: 203942_s_at
| Cell line | Expression level | Expression bar |
|---|---|---|
| ||
| 721_B_lymphoblasts | 5.4 | |
| Adipocyte | 4.05 | |
| AdrenalCortex | 4.3 | |
| Adrenalgland | 3.5 | |
| Amygdala | 4.35 | |
| Appendix | 4.1 | |
| AtrioventricularNode | 3.15 | |
| BDCA4+_DentriticCells | 5.3 | |
| Bonemarrow | 4.15 | |
| BronchialEpithelialCells | 4.1 | |
| CD105+_Endothelial | 4.15 | |
| CD14+_Monocytes | 7 | |
| CD19+_BCells(neg._sel.) | 5.15 | |
| CD33+_Myeloid | 7.5 | |
| CD34+ | 5.3 | |
| CD4+_Tcells | 6.6 | |
| CD56+_NKCells | 7.05 | |
| CD71+_EarlyErythroid | 4.15 | |
| CD8+_Tcells | 7.55 | |
| CardiacMyocytes | 5.05 | |
| Caudatenucleus | 3.65 | |
| Cerebellum | 3.35 | |
| CerebellumPeduncles | 4.65 | |
| CiliaryGanglion | 2.9 | |
| CingulateCortex | 4.6 | |
| Colorectaladenocarcinoma | 4.1 | |
| DorsalRootGanglion | 3.15 | |
| FetalThyroid | 4 | |
| Fetalbrain | 4.1 | |
| Fetalliver | 3.55 | |
| Fetallung | 3.35 | |
| GlobusPallidus | 3.1 | |
| Heart | 5.15 | |
| Hypothalamus | 4.45 | |
| Kidney | 3.3 | |
| Leukemia_chronicMyelogenousK-562 | 3.7 | |
| Leukemia_promyelocytic-HL-60 | 3.6 | |
| Leukemialymphoblastic(MOLT-4) | 3.3 | |
| Liver | 5.35 | |
| Lung | 4.75 | |
| Lymphnode | 3.45 | |
| Lymphoma_burkitts(Daudi) | 5.2 | |
| Lymphoma_burkitts(Raji) | 5.75 | |
| MedullaOblongata | 4 | |
| OccipitalLobe | 3.75 | |
| OlfactoryBulb | 3.3 | |
| Ovary | 2.7 | |
| Pancreas | 3.3 | |
| PancreaticIslet | 4.35 | |
| ParietalLobe | 4.35 | |
| Pituitary | 4.8 | |
| Placenta | 5.05 | |
| Pons | 3.95 | |
| PrefrontalCortex | 5.3 | |
| Prostate | 4.9 | |
| Salivarygland | 3.3 | |
| SkeletalMuscle | 6.3 | |
| Skin | 3.15 | |
| SmoothMuscle | 4.65 | |
| Spinalcord | 4.35 | |
| SubthalamicNucleus | 3.8 | |
| SuperiorCervicalGanglion | 4.6 | |
| TemporalLobe | 3.75 | |
| Testis | 3.5 | |
| TestisGermCell | 3.45 | |
| TestisIntersitial | 3.45 | |
| TestisLeydigCell | 4.35 | |
| TestisSeminiferousTubule | 3.55 | |
| Thalamus | 4.15 | |
| Thymus | 3.3 | |
| Thyroid | 5.15 | |
| Tongue | 4.15 | |
| Tonsil | 5 | |
| Trachea | 3.5 | |
| TrigeminalGanglion | 4.05 | |
| Uterus | 3.35 | |
| UterusCorpus | 3.65 | |
| WholeBlood | 4.6 | |
| Wholebrain | 3.5 | |
| colon | 4.2 | |
| pineal_day | 5.18 | |
| pineal_night | 5.08 | |
| retina | 5 | |
| small_intestine | 3.95 | |
- Probe name: A_24_P914495
- Donor H0351.2001
- Sex: Male Age: 24 years Race/Ethnicity: African American Handedness: Left
- Tissue Receipt Date: 7/29/2009 Serology: Pass Tissue pH :6.72 Additional Medical Information :History of asthma
- Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
- Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
| Tissue | Expression(mean ± stddev) | Expression Bar |
|---|---|---|
| Amygdala | 8.2 ± 0.44 | ![](../"images/bar_3.png"){kind=small}   |
| Basal Forebrain | 8.01 ± 0.22 | |
| Basal Part of Pons | 7.96 ± 0.43 | |
| Cerebellar Cortex | 7.77 ± 0.33 | |
| Cerebellar Nuclei | 7.81 ± 0.18 | |
| Claustrum | 8.39 ± 0.34 | |
| Epithalamus | 7.72 ± 0.32 | |
| Frontal Lobe | 7.88 ± 0.37 | |
| Globus Pallidus | 7.89 ± 0.21 | |
| Hypothalamus | 7.79 ± 0.38 | |
| Insula | 7.82 ± 0.27 | |
| Limbic Lobe | 8.14 ± 0.32 | |
| Mesencephalon | 7.9 ± 0.32 | |
| Myelencephalon | 7.95 ± 0.39 | |
| Occipital Lobe | 8.06 ± 0.35 | |
| Parietal Lobe | 7.96 ± 0.34 | |
| Pontine Tegmentum | 7.92 ± 0.31 | |
| Striatum | 8.22 ± 0.33 | |
| Subthalamus | 7.79 ± 0.18 | |
| Temporal Lobe | 7.93 ± 0.34 | |
| Thalamus | 7.79 ± 0.39 | |
| White Matter | 8.48 ± 0.31 | |
Mouse Brain ISH 
| Gene Symbol | Brain Structure ID | Brain Structure Name | Express Desity/Level (Meatured by ISH) | Express Bar |
|---|---|---|---|---|
| Mark2 | CB | Cerebellum | 35.24 | |
| 43.64 | | |||
| Mark2 | CTX | Cerebral cortex | 100 | |
| 94.42 | | |||
| Mark2 | HIP | Hippocampal region | 81.43 | |
| 100 | | |||
| Mark2 | HPF | Hippocampal formation | 77.28 | |
| 93.86 | | |||
| Mark2 | HY | Hypothalamus | 41.06 | |
| 31.77 | | |||
| Mark2 | LSX | Lateral septal complex | 47.05 | |
| 34.29 | | |||
| Mark2 | MB | Midbrain | 42.95 | |
| 37.65 | | |||
| Mark2 | MY | Medulla | 47.32 | |
| 47.06 | | |||
| Mark2 | OLF | Olfactory bulb | 90.43 | |
| 86.68 | | |||
| Mark2 | P | Pons | 38.87 | |
| 37.6 | | |||
| Mark2 | PAL | Pallidum | 34.2 | |
| 27.93 | | |||
| Mark2 | RHP | Retrohippocampal region | 70.23 | |
| 57.55 | | |||
| Mark2 | sAMY | Striatum-like amygdalar nuclei | 34.47 | |
| 23.17 | | |||
| Mark2 | STR | Striatum | 100 | |
| 83.4 | | |||
| Mark2 | STRd | Striatum dorsal region | 100 | |
| 97.23 | | |||
| Mark2 | STRv | Striatum ventral region | 99.21 | |
| 75.95 | | |||
| Mark2 | TH | Thalamus | 40 | |
| 34.91 | |
| Peptide Name | Peptide Lengh | Peptide Start | Peptide End | Peptide Sequence | Source |
|---|---|---|---|---|---|
| PAp00072636 | 19 | 206 | 224 | LDTFCGSPPYAAPELFQGK | Peptide Atlas |