AutismKB 2.0

Annotation Detail for EMP2


View Evidences View Variants View Annotations
Basic Information Top
Gene Symbol:EMP2 ( MGC9056,XMP )
Gene Full Name: epithelial membrane protein 2
Band: 16p13.13
Quick LinksEntrez ID:2013; OMIM: 602334; Uniprot ID:EMP2_HUMAN; ENSEMBL ID: ENSG00000213853; HGNC ID: 3334
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body3 / 7076142
blastocyst0 / 623190 
fetus42 / 56401274
neonate1 / 3109732
infant1 / 2362042
juvenile2 / 5555635
adult222 / 1939121114
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor1 / 1279478
bladder carcinoma0 / 174750 
breast (mammary gland) tumor20 / 94178212
cervical tumor4 / 34366116
chondrosarcoma10 / 82823120
colorectal tumor14 / 114246122
esophageal tumor1 / 1729057
gastrointestinal tumor12 / 119369100
germ cell tumor5 / 26384518
glioma1 / 1068839
head and neck tumor22 / 136302161
kidney tumor2 / 6895929
leukemia0 / 958420 
liver tumor5 / 9635951
lung tumor8 / 10312777
lymphoma0 / 717550 
non-neoplasia8 / 9725082
normal228 / 336030767
ovarian tumor4 / 7668252
pancreatic tumor3 / 10461628
primitive neuroectodermal tumor of the CNS2 / 12568015
prostate cancer3 / 10268029
retinoblastoma4 / 4635686
skin tumor8 / 12494964
soft tissue/muscle tissue tumor0 / 1251910 
uterine tumor7 / 9025777
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue1 / 1310676
adrenal gland1 / 3319730
ascites6 / 40015149
bladder8 / 29757268
blood0 / 1234780 
bone10 / 71655139
bone marrow0 / 488010 
brain11 / 11009899
cervix4 / 4817183
connective tissue10 / 14925566
ear3 / 16212185
embryonic tissue5 / 21572223
esophagus1 / 2020949
eye15 / 21105471
heart23 / 89626256
intestine31 / 234472132
kidney3 / 21177714
larynx7 / 24145289
liver12 / 20774357
lung84 / 336974249
lymph0 / 442700 
lymph node0 / 916100 
mammary gland25 / 153271163
mouth4 / 6705259
muscle3 / 10771527
nerve0 / 157680 
ovary4 / 10205139
pancreas11 / 21481251
parathyroid13 / 20539632
pharynx1 / 4132824
pituitary gland0 / 165850 
placenta19 / 28082567
prostate11 / 18934558
salivary gland3 / 20155148
skin23 / 210574109
spleen1 / 5395218
stomach6 / 9661962
testis5 / 33044215
thymus0 / 811310 
thyroid9 / 47473189
tonsil0 / 169990 
trachea3 / 5241357
umbilical cord0 / 136800 
uterus14 / 23287860
vascular0 / 517800 
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 204975_at
Cell line Expression level Expression bar
721_B_lymphoblasts6.2
Adipocyte6.85
AdrenalCortex6.6
Adrenalgland8.2
Amygdala6.95
Appendix7.8
AtrioventricularNode7.7
BDCA4+_DentriticCells5.55
Bonemarrow6.45
BronchialEpithelialCells9.1
CD105+_Endothelial6
CD14+_Monocytes5.95
CD19+_BCells(neg._sel.)5.5
CD33+_Myeloid7.05
CD34+6.7
CD4+_Tcells5.6
CD56+_NKCells5.95
CD71+_EarlyErythroid5
CD8+_Tcells4.65
CardiacMyocytes7.95
Caudatenucleus5.45
Cerebellum5.4
CerebellumPeduncles7.4
CiliaryGanglion16.25
CingulateCortex6.55
Colorectaladenocarcinoma20.6
DorsalRootGanglion69
FetalThyroid14.35
Fetalbrain5.3
Fetalliver5.75
Fetallung211.5
GlobusPallidus4.75
Heart43.5
Hypothalamus8.3
Kidney5.3
Leukemia_chronicMyelogenousK-5625.8
Leukemia_promyelocytic-HL-604.85
Leukemialymphoblastic(MOLT-4)4.4
Liver68.8
Lung1312.85
Lymphnode5.8
Lymphoma_burkitts(Daudi)7.9
Lymphoma_burkitts(Raji)8.4
MedullaOblongata5.35
OccipitalLobe5.6
OlfactoryBulb159.8
Ovary40.45
Pancreas6.9
PancreaticIslet19.6
ParietalLobe6.6
Pituitary9.95
Placenta289.75
Pons6.05
PrefrontalCortex8.95
Prostate104.7
Salivarygland35.85
SkeletalMuscle8.55
Skin74.8
SmoothMuscle7.65
Spinalcord6.65
SubthalamicNucleus5.75
SuperiorCervicalGanglion10.2
TemporalLobe5.5
Testis5.65
TestisGermCell5.15
TestisIntersitial5.2
TestisLeydigCell6.7
TestisSeminiferousTubule5.75
Thalamus6.2
Thymus7.45
Thyroid11.05
Tongue86.1
Tonsil36.4
Trachea33.8
TrigeminalGanglion15.05
Uterus36.9
UterusCorpus6.05
WholeBlood6.05
Wholebrain5.85
colon115.65
pineal_day7.42
pineal_night7.32
retina82.95
small_intestine123.7
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: A_23_P304682
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala6.17 ± 0.41
Basal Forebrain6.16 ± 0.27
Basal Part of Pons5.32 ± 0.32
Cerebellar Cortex5.62 ± 0.25
Cerebellar Nuclei6.56 ± 0.35
Claustrum5.45 ± 0.54
Epithalamus6.82 ± 0.34
Frontal Lobe5.97 ± 0.47
Globus Pallidus7.21 ± 0.38
Hypothalamus6.23 ± 0.28
Insula5.9 ± 0.29
Limbic Lobe5.88 ± 0.59
Mesencephalon6.31 ± 0.48
Myelencephalon6.1 ± 0.52
Occipital Lobe6.22 ± 0.51
Parietal Lobe5.93 ± 0.54
Pontine Tegmentum6.19 ± 0.41
Striatum6.83 ± 0.4
Subthalamus5.93 ± 0.13
Temporal Lobe5.91 ± 0.38
Thalamus6.25 ± 0.34
White Matter6.08 ± 0.67
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Emp2CBCerebellum27.36
38.61
Emp2CTXCerebral cortex79.26
65.12
Emp2HIPHippocampal region48.61
83.46
Emp2HPFHippocampal formation53.62
71.37
Emp2HYHypothalamus27.66
24.09
Emp2LSXLateral septal complex27.15
20.66
Emp2MBMidbrain38.15
36.57
Emp2MYMedulla41.71
46.19
Emp2OLFOlfactory bulb68.36
62.33
Emp2PPons34.85
41
Emp2PALPallidum33.07
33.46
Emp2RHPRetrohippocampal region63.51
57.4
Emp2sAMYStriatum-like amygdalar nuclei43.44
34.92
Emp2STRStriatum34.33
26.95
Emp2STRdStriatum dorsal region32.53
25.39
Emp2STRvStriatum ventral region38.63
29.98
Emp2THThalamus24.84
21.53
Peptide Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


Copyright © 2017, Center for Bioinformatics , Peking University | All Rights Reserved