AutismKB 2.0

Annotation Detail for ENDOG


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Basic Information Top
Gene Symbol:ENDOG ( FLJ27463 )
Gene Full Name: endonuclease G
Band: 9q34.11
Quick LinksEntrez ID:2021; OMIM: 600440; Uniprot ID:NUCG_HUMAN; ENSEMBL ID: ENSG00000167136; HGNC ID: 3346
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Microarray in BioGPS Top
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  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 204824_at
Cell line Expression level Expression bar
721_B_lymphoblasts10.6
Adipocyte10.35
AdrenalCortex6.25
Adrenalgland7.55
Amygdala12.2
Appendix4.75
AtrioventricularNode6.2
BDCA4+_DentriticCells15.8
Bonemarrow6.75
BronchialEpithelialCells23.8
CD105+_Endothelial33.5
CD14+_Monocytes11.15
CD19+_BCells(neg._sel.)8.75
CD33+_Myeloid12.25
CD34+20.15
CD4+_Tcells9.15
CD56+_NKCells9.5
CD71+_EarlyErythroid15.75
CD8+_Tcells7.25
CardiacMyocytes12.6
Caudatenucleus12.65
Cerebellum10.3
CerebellumPeduncles18.5
CiliaryGanglion5.15
CingulateCortex9.5
Colorectaladenocarcinoma7.95
DorsalRootGanglion5.15
FetalThyroid9.55
Fetalbrain22.35
Fetalliver6.35
Fetallung7
GlobusPallidus12.35
Heart132.6
Hypothalamus19.85
Kidney12.5
Leukemia_chronicMyelogenousK-56234.4
Leukemia_promyelocytic-HL-605.4
Leukemialymphoblastic(MOLT-4)23.1
Liver369.05
Lung17.9
Lymphnode5.8
Lymphoma_burkitts(Daudi)9.15
Lymphoma_burkitts(Raji)11.1
MedullaOblongata9.9
OccipitalLobe13.6
OlfactoryBulb5.45
Ovary4.45
Pancreas6.6
PancreaticIslet10.9
ParietalLobe12.4
Pituitary9.2
Placenta7.7
Pons8.1
PrefrontalCortex25.4
Prostate19.35
Salivarygland3.55
SkeletalMuscle10.25
Skin5.05
SmoothMuscle8.55
Spinalcord9.45
SubthalamicNucleus8.05
SuperiorCervicalGanglion5.65
TemporalLobe22
Testis33.8
TestisGermCell9.8
TestisIntersitial5.95
TestisLeydigCell12.95
TestisSeminiferousTubule11.8
Thalamus38.75
Thymus7.05
Thyroid13.35
Tongue8.55
Tonsil6.85
Trachea7.25
TrigeminalGanglion7.6
Uterus5.15
UterusCorpus5.9
WholeBlood7.45
Wholebrain78.25
colon8.2
pineal_day6.9
pineal_night6.26
retina9.45
small_intestine6.85
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: CUST_14464_PI416261804
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala4.98 ± 0.61
Basal Forebrain4.58 ± 0.36
Basal Part of Pons4.69 ± 0.5
Cerebellar Cortex4.41 ± 0.7
Cerebellar Nuclei4.64 ± 0.58
Claustrum5.25 ± 0.87
Epithalamus4.43 ± 0.43
Frontal Lobe4.86 ± 0.57
Globus Pallidus5.26 ± 0.57
Hypothalamus4.23 ± 0.69
Insula4.6 ± 0.57
Limbic Lobe4.92 ± 0.77
Mesencephalon4.51 ± 0.61
Myelencephalon4.83 ± 0.71
Occipital Lobe4.67 ± 0.6
Parietal Lobe4.77 ± 0.58
Pontine Tegmentum4.68 ± 0.76
Striatum4.7 ± 0.64
Subthalamus4.57 ± 0.32
Temporal Lobe4.79 ± 0.62
Thalamus4.81 ± 0.55
White Matter4.63 ± 0.75
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
EndogCBCerebellum0.44
0.89
EndogCTXCerebral cortex0.24
0.41
EndogHIPHippocampal region0.25
0.49
EndogHPFHippocampal formation0.21
0.43
EndogHYHypothalamus0.09
0.11
EndogLSXLateral septal complex0.63
0.78
EndogMBMidbrain0.31
0.46
EndogMYMedulla0.65
0.9
EndogOLFOlfactory bulb0.47
1.14
EndogPPons0.28
0.33
EndogPALPallidum0.1
0.14
EndogRHPRetrohippocampal region0.14
0.33
EndogsAMYStriatum-like amygdalar nuclei0.08
0.15
EndogSTRStriatum0.13
0.19
EndogSTRdStriatum dorsal region0.04
0.09
EndogSTRvStriatum ventral region0.13
0.24
EndogTHThalamus0.49
0.69
Peptide Top

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  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018