Annotation Detail for ENG
Basic Information Top
| Gene Symbol: | ENG ( CD105,END,FLJ41744,HHT1,ORW,ORW1 ) |
|---|---|
| Gene Full Name: | endoglin |
| Band: | 9q34.11 |
| Quick Links | Entrez ID:2022; OMIM: 131195; Uniprot ID:EGLN_HUMAN; ENSEMBL ID: ENSG00000106991; HGNC ID: 3349 |
| Relate to Another Database: | SFARIGene; denovo-db |
- Unigene ID: Hs.76753
| Pool Name | Gene EST/Total EST in pool | Transcripts per million(TPM) | Bar based on TPM |
|---|---|---|---|
 | |||
| embryoid body | 2 / 70761 | 28 |  |
| blastocyst | 0 / 62319 | 0 | |
| fetus | 90 / 564012 | 159 |  |
| neonate | 44 / 31097 | 1414 |  |
| infant | 0 / 23620 | 0 | |
| juvenile | 14 / 55556 | 251 |  |
| adult | 385 / 1939121 | 198 | |
| Pool Name | Gene EST/Total EST in pool | Transcripts per million(TPM) | Bar based on TPM |
|---|---|---|---|
| |||
| adrenal tumor | 0 / 12794 | 0 | |
| bladder carcinoma | 1 / 17475 | 57 | |
| breast (mammary gland) tumor | 18 / 94178 | 191 | |
| cervical tumor | 4 / 34366 | 116 | |
| chondrosarcoma | 29 / 82823 | 350 | |
| colorectal tumor | 3 / 114246 | 26 | |
| esophageal tumor | 2 / 17290 | 115 | |
| gastrointestinal tumor | 3 / 119369 | 25 | |
| germ cell tumor | 13 / 263845 | 49 | |
| glioma | 13 / 106883 | 121 | |
| head and neck tumor | 57 / 136302 | 418 | |
| kidney tumor | 7 / 68959 | 101 | |
| leukemia | 25 / 95842 | 260 | |
| liver tumor | 2 / 96359 | 20 | |
| lung tumor | 8 / 103127 | 77 | |
| lymphoma | 1 / 71755 | 13 | |
| non-neoplasia | 114 / 97250 | 1172 | |
| normal | 1335 / 3360307 | 397 | |
| ovarian tumor | 11 / 76682 | 143 | |
| pancreatic tumor | 14 / 104616 | 133 | |
| primitive neuroectodermal tumor of the CNS | 13 / 125680 | 103 | |
| prostate cancer | 4 / 102680 | 38 | |
| retinoblastoma | 0 / 46356 | 0 | |
| skin tumor | 12 / 124949 | 96 | |
| soft tissue/muscle tissue tumor | 7 / 125191 | 55 | |
| uterine tumor | 7 / 90257 | 77 | |
| Pool Name | Gene EST/Total EST in pool | Transcripts per million(TPM) | Bar based on TPM |
|---|---|---|---|
| |||
| adipose tissue | 3 / 13106 | 228 | |
| adrenal gland | 13 / 33197 | 391 | |
| ascites | 0 / 40015 | 0 | |
| bladder | 0 / 29757 | 0 | |
| blood | 15 / 123478 | 121 | |
| bone | 13 / 71655 | 181 | |
| bone marrow | 6 / 48801 | 122 | |
| brain | 190 / 1100989 | 172 | |
| cervix | 7 / 48171 | 145 | |
| connective tissue | 136 / 149255 | 911 | |
| ear | 0 / 16212 | 0 | |
| embryonic tissue | 4 / 215722 | 18 | |
| esophagus | 4 / 20209 | 197 | |
| eye | 31 / 211054 | 146 | |
| heart | 51 / 89626 | 569 | |
| intestine | 54 / 234472 | 230 | |
| kidney | 133 / 211777 | 628 | |
| larynx | 4 / 24145 | 165 | |
| liver | 18 / 207743 | 86 | |
| lung | 166 / 336974 | 492 | |
| lymph | 0 / 44270 | 0 | |
| lymph node | 6 / 91610 | 65 | |
| mammary gland | 34 / 153271 | 221 | |
| mouth | 46 / 67052 | 686 | |
| muscle | 10 / 107715 | 92 | |
| nerve | 5 / 15768 | 317 | |
| ovary | 15 / 102051 | 146 | |
| pancreas | 37 / 214812 | 172 | |
| parathyroid | 4 / 20539 | 194 | |
| pharynx | 0 / 41328 | 0 | |
| pituitary gland | 1 / 16585 | 60 | |
| placenta | 161 / 280825 | 573 | |
| prostate | 37 / 189345 | 195 | |
| salivary gland | 5 / 20155 | 248 | |
| skin | 88 / 210574 | 417 | |
| spleen | 155 / 53952 | 2872 | |
| stomach | 9 / 96619 | 93 | |
| testis | 185 / 330442 | 559 | |
| thymus | 92 / 81131 | 1133 | |
| thyroid | 21 / 47473 | 442 | |
| tonsil | 0 / 16999 | 0 | |
| trachea | 9 / 52413 | 171 | |
| umbilical cord | 7 / 13680 | 511 | |
| uterus | 59 / 232878 | 253 | |
| vascular | 163 / 51780 | 3147 | |
- Microarray Platform: GeneAtlas U133A, gcrma
- Affymatrix Probe ID: 201808_s_at
| Cell line | Expression level | Expression bar |
|---|---|---|
| ||
| 721_B_lymphoblasts | 5.65 |  |
| Adipocyte | 4.85 | |
| AdrenalCortex | 5.05 | |
| Adrenalgland | 4.15 | |
| Amygdala | 5.25 | |
| Appendix | 5.05 | |
| AtrioventricularNode | 3.8 | |
| BDCA4+_DentriticCells | 5.15 | |
| Bonemarrow | 4.85 | |
| BronchialEpithelialCells | 4.9 | |
| CD105+_Endothelial | 5 | |
| CD14+_Monocytes | 5.25 | |
| CD19+_BCells(neg._sel.) | 5.3 | |
| CD33+_Myeloid | 5.9 | |
| CD34+ | 6.25 | |
| CD4+_Tcells | 5 | |
| CD56+_NKCells | 5.45 | |
| CD71+_EarlyErythroid | 4.55 | |
| CD8+_Tcells | 4.5 | |
| CardiacMyocytes | 20 | |
| Caudatenucleus | 4.4 | |
| Cerebellum | 4 | |
| CerebellumPeduncles | 5.55 | |
| CiliaryGanglion | 3.55 | |
| CingulateCortex | 5 | |
| Colorectaladenocarcinoma | 4.95 | |
| DorsalRootGanglion | 3.75 | |
| FetalThyroid | 5.05 | |
| Fetalbrain | 4.9 | |
| Fetalliver | 4.25 | |
| Fetallung | 4.15 | |
| GlobusPallidus | 3.55 | |
| Heart | 6.5 | |
| Hypothalamus | 5.3 | |
| Kidney | 4 | |
| Leukemia_chronicMyelogenousK-562 | 4.45 | |
| Leukemia_promyelocytic-HL-60 | 4.3 | |
| Leukemialymphoblastic(MOLT-4) | 3.95 | |
| Liver | 6.4 | |
| Lung | 17.75 | |
| Lymphnode | 4.3 | |
| Lymphoma_burkitts(Daudi) | 6.25 | |
| Lymphoma_burkitts(Raji) | 6.8 | |
| MedullaOblongata | 4.55 | |
| OccipitalLobe | 4.4 | |
| OlfactoryBulb | 3.9 | |
| Ovary | 5.7 | |
| Pancreas | 3.95 | |
| PancreaticIslet | 5.25 | |
| ParietalLobe | 5.1 | |
| Pituitary | 5.75 | |
| Placenta | 8.55 | |
| Pons | 4.7 | |
| PrefrontalCortex | 6.25 | |
| Prostate | 5.8 | |
| Salivarygland | 3.95 | |
| SkeletalMuscle | 5.65 | |
| Skin | 3.9 | |
| SmoothMuscle | 7.7 | |
| Spinalcord | 5.25 | |
| SubthalamicNucleus | 4.45 | |
| SuperiorCervicalGanglion | 5.75 | |
| TemporalLobe | 4.5 | |
| Testis | 4.25 | |
| TestisGermCell | 4.1 | |
| TestisIntersitial | 4.75 | |
| TestisLeydigCell | 4.9 | |
| TestisSeminiferousTubule | 4.25 | |
| Thalamus | 4.95 | |
| Thymus | 3.95 | |
| Thyroid | 7.4 | |
| Tongue | 4.8 | |
| Tonsil | 5.1 | |
| Trachea | 4.15 | |
| TrigeminalGanglion | 5.25 | |
| Uterus | 4.1 | |
| UterusCorpus | 4.35 | |
| WholeBlood | 5.45 | |
| Wholebrain | 4.15 | |
| colon | 4.95 | |
| pineal_day | 5.94 | |
| pineal_night | 5.9 | |
| retina | 5.975 | |
| small_intestine | 4.8 | |
- Probe name: A_23_P83328
- Donor H0351.2001
- Sex: Male Age: 24 years Race/Ethnicity: African American Handedness: Left
- Tissue Receipt Date: 7/29/2009 Serology: Pass Tissue pH :6.72 Additional Medical Information :History of asthma
- Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
- Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
| Tissue | Expression(mean ± stddev) | Expression Bar |
|---|---|---|
| Amygdala | 3.57 ± 0.43 | ![](../"images/bar_3.png"){kind=small}   |
| Basal Forebrain | 3.29 ± 0.43 | |
| Basal Part of Pons | 3.79 ± 0.48 | |
| Cerebellar Cortex | 3.55 ± 0.63 | |
| Cerebellar Nuclei | 4.19 ± 0.48 | |
| Claustrum | 3.43 ± 0.64 | |
| Epithalamus | 3.3 ± 0.91 | |
| Frontal Lobe | 3.83 ± 0.63 | |
| Globus Pallidus | 4.17 ± 0.35 | |
| Hypothalamus | 3.1 ± 0.43 | |
| Insula | 3.74 ± 0.61 | |
| Limbic Lobe | 3.64 ± 0.64 | |
| Mesencephalon | 3.84 ± 0.63 | |
| Myelencephalon | 3.85 ± 0.64 | |
| Occipital Lobe | 3.93 ± 0.74 | |
| Parietal Lobe | 3.42 ± 0.67 | |
| Pontine Tegmentum | 3.71 ± 0.77 | |
| Striatum | 4.45 ± 0.58 | |
| Subthalamus | 3.91 ± 0.62 | |
| Temporal Lobe | 3.69 ± 0.55 | |
| Thalamus | 4.1 ± 0.73 | |
| White Matter | 3.79 ± 0.96 | |
Mouse Brain ISH 
| Gene Symbol | Brain Structure ID | Brain Structure Name | Express Desity/Level (Meatured by ISH) | Express Bar |
|---|---|---|---|---|
| Eng | CB | Cerebellum | 3.46 | |
| 5.54 | | |||
| Eng | CTX | Cerebral cortex | 7.63 | |
| 6.59 | | |||
| Eng | HIP | Hippocampal region | 7.12 | |
| 8.82 | | |||
| Eng | HPF | Hippocampal formation | 6.62 | |
| 7.6 | | |||
| Eng | HY | Hypothalamus | 6.88 | |
| 6.53 | | |||
| Eng | LSX | Lateral septal complex | 4.66 | |
| 4.43 | | |||
| Eng | MB | Midbrain | 5.74 | |
| 8.24 | | |||
| Eng | MY | Medulla | 4.56 | |
| 8.83 | | |||
| Eng | OLF | Olfactory bulb | 7.79 | |
| 8.21 | | |||
| Eng | P | Pons | 6.88 | |
| 11.96 | | |||
| Eng | PAL | Pallidum | 3.03 | |
| 3.45 | | |||
| Eng | RHP | Retrohippocampal region | 5.35 | |
| 5.25 | | |||
| Eng | sAMY | Striatum-like amygdalar nuclei | 4.76 | |
| 5.13 | | |||
| Eng | STR | Striatum | 6.46 | |
| 5.75 | | |||
| Eng | STRd | Striatum dorsal region | 7.26 | |
| 6.5 | | |||
| Eng | STRv | Striatum ventral region | 5.8 | |
| 4.52 | | |||
| Eng | TH | Thalamus | 6 | |
| 7.21 | |
| Peptide Name | Peptide Lengh | Peptide Start | Peptide End | Peptide Sequence | Source |
|---|---|---|---|---|---|
| EGLN_HUMAN_26 | 14 | 26 | 39 | ETVHCDLQPVGPER | PRIDE |
| PAp00010172 | 11 | 206 | 216 | GCHLEGVAGHK | Peptide Atlas |