AutismKB 2.0

Annotation Detail for ENO1


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Basic Information Top
Gene Symbol:ENO1 ( ENO1L1,MPB1,NNE,PPH )
Gene Full Name: enolase 1, (alpha)
Band: 1p36.23
Quick LinksEntrez ID:2023; OMIM: 172430; Uniprot ID:ENOA_HUMAN; ENSEMBL ID: ENSG00000074800; HGNC ID: 3350
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body135 / 707611907
blastocyst172 / 623192759
fetus363 / 564012643
neonate96 / 310973087
infant124 / 236205249
juvenile328 / 555565903
adult2801 / 19391211444
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor18 / 127941406
bladder carcinoma15 / 17475858
breast (mammary gland) tumor176 / 941781868
cervical tumor278 / 343668089
chondrosarcoma116 / 828231400
colorectal tumor286 / 1142462503
esophageal tumor96 / 172905552
gastrointestinal tumor332 / 1193692781
germ cell tumor731 / 2638452770
glioma295 / 1068832760
head and neck tumor235 / 1363021724
kidney tumor280 / 689594060
leukemia180 / 958421878
liver tumor479 / 963594970
lung tumor532 / 1031275158
lymphoma254 / 717553539
non-neoplasia317 / 972503259
normal4022 / 33603071196
ovarian tumor412 / 766825372
pancreatic tumor376 / 1046163594
primitive neuroectodermal tumor of the CNS617 / 1256804909
prostate cancer265 / 1026802580
retinoblastoma194 / 463564185
skin tumor742 / 1249495938
soft tissue/muscle tissue tumor286 / 1251912284
uterine tumor215 / 902572382
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue23 / 131061754
adrenal gland41 / 331971235
ascites149 / 400153723
bladder36 / 297571209
blood261 / 1234782113
bone123 / 716551716
bone marrow130 / 488012663
brain1885 / 11009891712
cervix304 / 481716310
connective tissue251 / 1492551681
ear3 / 16212185
embryonic tissue508 / 2157222354
esophagus111 / 202095492
eye464 / 2110542198
heart62 / 89626691
intestine477 / 2344722034
kidney703 / 2117773319
larynx17 / 24145704
liver642 / 2077433090
lung720 / 3369742136
lymph165 / 442703727
lymph node75 / 91610818
mammary gland259 / 1532711689
mouth51 / 67052760
muscle109 / 1077151011
nerve11 / 15768697
ovary490 / 1020514801
pancreas409 / 2148121903
parathyroid5 / 20539243
pharynx80 / 413281935
pituitary gland6 / 16585361
placenta593 / 2808252111
prostate302 / 1893451594
salivary gland75 / 201553721
skin828 / 2105743932
spleen45 / 53952834
stomach153 / 966191583
testis316 / 330442956
thymus137 / 811311688
thyroid124 / 474732612
tonsil50 / 169992941
trachea19 / 52413362
umbilical cord62 / 136804532
uterus409 / 2328781756
vascular242 / 517804673
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 217294_s_at
Cell line Expression level Expression bar
721_B_lymphoblasts6717.15
Adipocyte776.05
AdrenalCortex43.05
Adrenalgland104.55
Amygdala474.4
Appendix10.35
AtrioventricularNode12.55
BDCA4+_DentriticCells972.85
Bonemarrow616.4
BronchialEpithelialCells2853.4
CD105+_Endothelial69.9
CD14+_Monocytes994.6
CD19+_BCells(neg._sel.)229.75
CD33+_Myeloid1803.6
CD34+1514.95
CD4+_Tcells813.15
CD56+_NKCells696.4
CD71+_EarlyErythroid5.9
CD8+_Tcells570.75
CardiacMyocytes5496.95
Caudatenucleus383.85
Cerebellum422.05
CerebellumPeduncles270.1
CiliaryGanglion29.55
CingulateCortex93.6
Colorectaladenocarcinoma2268.75
DorsalRootGanglion58.35
FetalThyroid50.7
Fetalbrain172.55
Fetalliver71.4
Fetallung521.55
GlobusPallidus143.15
Heart165.95
Hypothalamus327.45
Kidney714.35
Leukemia_chronicMyelogenousK-5621112.95
Leukemia_promyelocytic-HL-603072.25
Leukemialymphoblastic(MOLT-4)1131.5
Liver839.8
Lung661.7
Lymphnode110.35
Lymphoma_burkitts(Daudi)564.35
Lymphoma_burkitts(Raji)1739.05
MedullaOblongata174.85
OccipitalLobe372.2
OlfactoryBulb34.05
Ovary309.45
Pancreas120.7
PancreaticIslet522.25
ParietalLobe293.05
Pituitary145.3
Placenta560.35
Pons171.9
PrefrontalCortex444.65
Prostate313.7
Salivarygland45.85
SkeletalMuscle11.85
Skin20.25
SmoothMuscle3363.85
Spinalcord253
SubthalamicNucleus127.15
SuperiorCervicalGanglion13.25
TemporalLobe227.75
Testis205.55
TestisGermCell74.6
TestisIntersitial89.15
TestisLeydigCell93.5
TestisSeminiferousTubule33.75
Thalamus89.8
Thymus933.25
Thyroid211.35
Tongue49.6
Tonsil783.2
Trachea198.35
TrigeminalGanglion33.65
Uterus108.7
UterusCorpus134.1
WholeBlood318.4
Wholebrain1090
colon598.25
pineal_day189.58
pineal_night196.14
retina814.6
small_intestine642.85
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: A_23_P137391
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala10.33 ± 0.34
Basal Forebrain9.85 ± 0.25
Basal Part of Pons10.29 ± 0.18
Cerebellar Cortex9.72 ± 0.24
Cerebellar Nuclei10.16 ± 0.34
Claustrum9.48 ± 0.44
Epithalamus9.9 ± 0.35
Frontal Lobe10.12 ± 0.38
Globus Pallidus10.02 ± 0.28
Hypothalamus10 ± 0.31
Insula10.23 ± 0.29
Limbic Lobe10.19 ± 0.4
Mesencephalon9.86 ± 0.36
Myelencephalon10.06 ± 0.38
Occipital Lobe9.68 ± 0.31
Parietal Lobe9.91 ± 0.39
Pontine Tegmentum9.93 ± 0.44
Striatum10.31 ± 0.32
Subthalamus9.84 ± 0.29
Temporal Lobe10.17 ± 0.39
Thalamus9.7 ± 0.29
White Matter9.37 ± 0.09
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Eno1CBCerebellum36.84
67.26
Eno1CTXCerebral cortex69.64
68.41
Eno1HIPHippocampal region45.28
78.93
Eno1HPFHippocampal formation47.91
68.8
Eno1HYHypothalamus9.12
9.46
Eno1LSXLateral septal complex1.94
1.94
Eno1MBMidbrain16.15
19.26
Eno1MYMedulla41.1
53.93
Eno1OLFOlfactory bulb39.36
38.24
Eno1PPons27.6
35.34
Eno1PALPallidum17.25
21.61
Eno1RHPRetrohippocampal region54.36
56.93
Eno1sAMYStriatum-like amygdalar nuclei11.26
10.66
Eno1STRStriatum13.08
12.86
Eno1STRdStriatum dorsal region12.74
12.91
Eno1STRvStriatum ventral region20.81
18.49
Eno1THThalamus26.18
29.43
Peptide Top
Peptide Name Peptide Lengh Peptide Start Peptide End Peptide Sequence Source
ENOA_HUMAN_0 0 0 0 AAVPSGASTGIYEALELR PRIDE
ENOA_HUMAN_0 0 0 0 DATNVGDEGGFAPNILENK PRIDE
ENOA_HUMAN_0 0 0 0 FTASAGIQVVGDDLTVTNPK PRIDE
ENOA_HUMAN_0 0 0 0 FTASAGIQVVGDDLTVTNPKR PRIDE
ENOA_HUMAN_0 0 0 0 GNPTVEVDLFTSK PRIDE
ENOA_HUMAN_0 0 0 0 SGKYDLDFKSPDDPSR PRIDE
ENOA_HUMAN_0 0 0 0 VNQIGSVTESLQACK PRIDE
ENOA_HUMAN_0 0 0 0 YISPDQLADLYK PRIDE
ENOA_HUMAN_1 8 1 8 SILKIHAR PRIDE
ENOA_HUMAN_103 17 103 119 SKFGANAILGVSLAVCK PRIDE
ENOA_HUMAN_105 15 105 119 FGANAILGVSLAVCK PRIDE
ENOA_HUMAN_106 21 106 126 FGANAILGVSLAVCKAGAVEK PRIDE
ENOA_HUMAN_121 11 121 131 GAVEKGVPLYR PRIDE
ENOA_HUMAN_132 30 132 161 HIADLAGNSEVILPVPAFNVINGGSHAGNK PRIDE
ENOA_HUMAN_133 30 133 162 HIADLAGNSEVILPVPAFNVINGGSHAGNK PRIDE
ENOA_HUMAN_15 13 15 27 GNPTVEVDLFTSK PRIDE
ENOA_HUMAN_16 13 16 28 GNPTVEVDLFTSK PRIDE
ENOA_HUMAN_162 17 162 178 LAMQEFMILPVGAANFR PRIDE
ENOA_HUMAN_163 17 163 179 LAMQEFMILPVGAANFR PRIDE
ENOA_HUMAN_183 10 183 192 IGAEVYHNLK PRIDE
ENOA_HUMAN_183 14 183 196 IGAEVYHNLKNVIK PRIDE
ENOA_HUMAN_184 10 184 193 IGAEVYHNLK PRIDE
ENOA_HUMAN_199 22 199 220 YGKDATNVGDEGGFAPNILENK PRIDE
ENOA_HUMAN_199 29 199 227 YGKDATNVGDEGGFAPNILENKEGLELLK PRIDE
ENOA_HUMAN_2 8 2 9 SILKIHAR PRIDE
ENOA_HUMAN_202 19 202 220 DATNVGDEGGFAPNILENK PRIDE
ENOA_HUMAN_202 26 202 227 DATNVGDEGGFAPNILENKEGLELLK PRIDE
ENOA_HUMAN_202 31 202 232 DATNVGDEGGFAPNILENKEGLELLKTAIGK PRIDE
ENOA_HUMAN_228 11 228 238 TAIGKAGYTDK PRIDE
ENOA_HUMAN_233 20 233 252 AGYTDKVVIGMDVAASEFFR PRIDE
ENOA_HUMAN_239 14 239 252 VVIGMDVAASEFFR PRIDE
ENOA_HUMAN_24 8 24 31 FTSKGLFR PRIDE
ENOA_HUMAN_240 17 240 256 VVIGMDVAASEFFRSGK PRIDE
ENOA_HUMAN_253 16 253 268 SGKYDLDFKSPDDPSR PRIDE
ENOA_HUMAN_253 9 253 261 SGKYDLDFK PRIDE
ENOA_HUMAN_254 16 254 269 SGKYDLDFKSPDDPSR PRIDE
ENOA_HUMAN_257 6 257 262 YDLDFK PRIDE
ENOA_HUMAN_269 12 269 280 YISPDQLADLYK PRIDE
ENOA_HUMAN_270 12 270 281 YISPDQLADLYK PRIDE
ENOA_HUMAN_281 25 281 305 SFIKDYPVVSIEDPFDQDDWGAWQK PRIDE
ENOA_HUMAN_285 21 285 305 DYPVVSIEDPFDQDDWGAWQK PRIDE
ENOA_HUMAN_286 21 286 306 DYPVVSIEDPFDQDDWGAWQK PRIDE
ENOA_HUMAN_306 20 306 325 FTASAGIQVVGDDLTVTNPK PRIDE
ENOA_HUMAN_306 21 306 326 FTASAGIQVVGDDLTVTNPKR PRIDE
ENOA_HUMAN_307 20 307 326 FTASAGIQVVGDDLTVTNPK PRIDE
ENOA_HUMAN_32 18 32 49 AAVPSGASTGIYEALELR PRIDE
ENOA_HUMAN_32 24 32 55 AAVPSGASTGIYEALELRDNDKTR PRIDE
ENOA_HUMAN_33 17 33 49 AVPSGASTGIYEALELR PRIDE
ENOA_HUMAN_33 18 33 50 AAVPSGASTGIYEALELR PRIDE
ENOA_HUMAN_335 8 335 342 SCNCLLLK PRIDE
ENOA_HUMAN_343 15 343 357 VNQIGSVTESLQACK PRIDE
ENOA_HUMAN_358 14 358 371 LAQANGWGVMVSHR PRIDE
ENOA_HUMAN_359 14 359 372 LAQANGWGVMVSHR PRIDE
ENOA_HUMAN_372 22 372 393 SGETEDTFIADLVVGLCTGQIK PRIDE
ENOA_HUMAN_372 28 372 399 SGETEDTFIADLVVGLCTGQIKTGAPCR PRIDE
ENOA_HUMAN_403 9 403 411 LAKYNQLLR PRIDE
ENOA_HUMAN_406 14 406 419 YNQLLRIEEELGSK PRIDE
ENOA_HUMAN_407 6 407 412 YNQLLR PRIDE
ENOA_HUMAN_412 10 412 421 IEEELGSKAK PRIDE
ENOA_HUMAN_412 14 412 425 IEEELGSKAKFAGR PRIDE
ENOA_HUMAN_412 8 412 419 IEEELGSK PRIDE
ENOA_HUMAN_413 13 413 425 EEELGSKAKFAGR PRIDE
ENOA_HUMAN_413 8 413 420 IEEELGSK PRIDE
ENOA_HUMAN_426 8 426 433 NFRNPLAK PRIDE
ENOA_HUMAN_64 16 64 79 AVEHINKTIAPALVSK PRIDE
ENOA_HUMAN_80 12 80 91 KLNVTEQEKIDK PRIDE
ENOA_HUMAN_81 11 81 91 LNVTEQEKIDK PRIDE
ENOA_HUMAN_81 22 81 102 LNVTEQEKIDKLMIEMDGTENK PRIDE
ENOA_HUMAN_89 14 89 102 IDKLMIEMDGTENK PRIDE
ENOA_HUMAN_92 11 92 102 LMIEMDGTENK PRIDE
ENOA_HUMAN_93 11 93 103 LMIEMDGTENK PRIDE
PAp00000191 18 33 50 AAVPSGASTGIYEALELR Peptide Atlas

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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