AutismKB 2.0

Annotation Detail for ENO2


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Basic Information Top
Gene Symbol:ENO2 ( NSE )
Gene Full Name: enolase 2 (gamma, neuronal)
Band: 12p13.31
Quick LinksEntrez ID:2026; OMIM: 131360; Uniprot ID:ENOG_HUMAN; ENSEMBL ID: ENSG00000111674; HGNC ID: 3353
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body0 / 707610 
blastocyst6 / 6231996
fetus130 / 564012230
neonate0 / 310970 
infant4 / 23620169
juvenile8 / 55556143
adult304 / 1939121156
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor3 / 12794234
bladder carcinoma0 / 174750 
breast (mammary gland) tumor3 / 9417831
cervical tumor1 / 3436629
chondrosarcoma11 / 82823132
colorectal tumor3 / 11424626
esophageal tumor1 / 1729057
gastrointestinal tumor3 / 11936925
germ cell tumor115 / 263845435
glioma22 / 106883205
head and neck tumor13 / 13630295
kidney tumor54 / 68959783
leukemia8 / 9584283
liver tumor2 / 9635920
lung tumor18 / 103127174
lymphoma2 / 7175527
non-neoplasia10 / 97250102
normal940 / 3360307279
ovarian tumor1 / 7668213
pancreatic tumor6 / 10461657
primitive neuroectodermal tumor of the CNS24 / 125680190
prostate cancer0 / 1026800 
retinoblastoma19 / 46356409
skin tumor6 / 12494948
soft tissue/muscle tissue tumor2 / 12519115
uterine tumor8 / 9025788
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland5 / 33197150
ascites0 / 400150 
bladder0 / 297570 
blood9 / 12347872
bone3 / 7165541
bone marrow0 / 488010 
brain911 / 1100989827
cervix2 / 4817141
connective tissue9 / 14925560
ear1 / 1621261
embryonic tissue13 / 21572260
esophagus1 / 2020949
eye97 / 211054459
heart2 / 8962622
intestine5 / 23447221
kidney62 / 211777292
larynx6 / 24145248
liver5 / 20774324
lung27 / 33697480
lymph2 / 4427045
lymph node2 / 9161021
mammary gland9 / 15327158
mouth3 / 6705244
muscle2 / 10771518
nerve5 / 15768317
ovary2 / 10205119
pancreas23 / 214812107
parathyroid1 / 2053948
pharynx0 / 413280 
pituitary gland5 / 16585301
placenta5 / 28082517
prostate0 / 1893450 
salivary gland0 / 201550 
skin9 / 21057442
spleen1 / 5395218
stomach3 / 9661931
testis66 / 330442199
thymus14 / 81131172
thyroid3 / 4747363
tonsil1 / 1699958
trachea4 / 5241376
umbilical cord0 / 136800 
uterus13 / 23287855
vascular4 / 5178077
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 201313_at
Cell line Expression level Expression bar
721_B_lymphoblasts731.85
Adipocyte4.5
AdrenalCortex5.1
Adrenalgland5.4
Amygdala746.65
Appendix7.85
AtrioventricularNode3.65
BDCA4+_DentriticCells4.95
Bonemarrow4.65
BronchialEpithelialCells4.45
CD105+_Endothelial6.1
CD14+_Monocytes4.25
CD19+_BCells(neg._sel.)5
CD33+_Myeloid5.75
CD34+8.35
CD4+_Tcells120.75
CD56+_NKCells5.1
CD71+_EarlyErythroid5.75
CD8+_Tcells108
CardiacMyocytes8.55
Caudatenucleus471.9
Cerebellum1456.55
CerebellumPeduncles1707.35
CiliaryGanglion29.25
CingulateCortex637
Colorectaladenocarcinoma44.8
DorsalRootGanglion71.3
FetalThyroid7.85
Fetalbrain423.55
Fetalliver4
Fetallung5.4
GlobusPallidus454.15
Heart6.2
Hypothalamus748.15
Kidney3.8
Leukemia_chronicMyelogenousK-5626.75
Leukemia_promyelocytic-HL-6034.15
Leukemialymphoblastic(MOLT-4)94.55
Liver6.2
Lung4.95
Lymphnode11.05
Lymphoma_burkitts(Daudi)36.5
Lymphoma_burkitts(Raji)5.9
MedullaOblongata654.5
OccipitalLobe840.25
OlfactoryBulb12.25
Ovary4.6
Pancreas4.85
PancreaticIslet52.5
ParietalLobe672.6
Pituitary112.95
Placenta4.65
Pons351.4
PrefrontalCortex1463.95
Prostate4.95
Salivarygland3.7
SkeletalMuscle5.6
Skin3.6
SmoothMuscle19
Spinalcord179.9
SubthalamicNucleus586.1
SuperiorCervicalGanglion15.35
TemporalLobe547.1
Testis4
TestisGermCell3.55
TestisIntersitial3.4
TestisLeydigCell4.55
TestisSeminiferousTubule3.9
Thalamus914.6
Thymus6.35
Thyroid11.3
Tongue4.55
Tonsil4.65
Trachea3.85
TrigeminalGanglion24
Uterus4.65
UterusCorpus22.8
WholeBlood4.6
Wholebrain892.65
colon3.3
pineal_day3887.94
pineal_night3293.16
retina1265.025
small_intestine4.05
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: CUST_15875_PI416261804
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala9.68 ± 0.26
Basal Forebrain9.36 ± 0.2
Basal Part of Pons10.08 ± 0.34
Cerebellar Cortex9.84 ± 0.26
Cerebellar Nuclei9.68 ± 0.29
Claustrum10.21 ± 0.54
Epithalamus8.67 ± 0.61
Frontal Lobe9.61 ± 0.41
Globus Pallidus8.72 ± 0.35
Hypothalamus9.69 ± 0.23
Insula9.48 ± 0.4
Limbic Lobe9.65 ± 0.5
Mesencephalon9.55 ± 0.56
Myelencephalon9.57 ± 0.49
Occipital Lobe9.89 ± 0.41
Parietal Lobe9.74 ± 0.41
Pontine Tegmentum9.64 ± 0.4
Striatum9.34 ± 0.42
Subthalamus9.62 ± 0.17
Temporal Lobe9.66 ± 0.35
Thalamus9.82 ± 0.37
White Matter7.82 ± 0.37
Mouse Brain ISH
Peptide Top
Peptide Name Peptide Lengh Peptide Start Peptide End Peptide Sequence Source
ENOG_HUMAN_103 17 103 119 SKFGANAILGVSLAVCK PRIDE
ENOG_HUMAN_105 15 105 119 FGANAILGVSLAVCK PRIDE
ENOG_HUMAN_15 13 15 27 GNPTVEVDLYTAK PRIDE
ENOG_HUMAN_16 13 16 28 GNPTVEVDLYTAK PRIDE
ENOG_HUMAN_162 17 162 178 LAMQEFMILPVGAESFR PRIDE
ENOG_HUMAN_239 14 239 252 IVIGMDVAASEFYR PRIDE
ENOG_HUMAN_257 6 257 262 YDLDFK PRIDE
ENOG_HUMAN_269 16 269 284 YITGDQLGALYQDFVR PRIDE
ENOG_HUMAN_32 18 32 49 AAVPSGASTGIYEALELR PRIDE
ENOG_HUMAN_33 18 33 50 AAVPSGASTGIYEALELR PRIDE
ENOG_HUMAN_343 15 343 357 VNQIGSVTEAIQACK PRIDE
ENOG_HUMAN_372 22 372 393 SGETEDTFIADLVVGLCTGQIK PRIDE
PAp00000191 18 33 50 AAVPSGASTGIYEALELR Peptide Atlas

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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