AutismKB 2.0

Annotation Detail for ANKS6


View Evidences View Variants View Annotations
Basic Information Top
Gene Symbol:ANKS6 ( ANKRD14,DKFZp686D24121,DKFZp781I0117,MGC70366,SAMD6 )
Gene Full Name: ankyrin repeat and sterile alpha motif domain containing 6
Band: 9q22.33
Quick LinksEntrez ID:203286; OMIM: NA; Uniprot ID:ANKS6_HUMAN; ENSEMBL ID: ENSG00000165138; HGNC ID: 26724
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body3 / 7076142
blastocyst5 / 6231980
fetus12 / 56401221
neonate0 / 310970 
infant0 / 236200 
juvenile4 / 5555671
adult64 / 193912133
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor1 / 1279478
bladder carcinoma0 / 174750 
breast (mammary gland) tumor3 / 9417831
cervical tumor1 / 3436629
chondrosarcoma4 / 8282348
colorectal tumor5 / 11424643
esophageal tumor0 / 172900 
gastrointestinal tumor9 / 11936975
germ cell tumor2 / 2638457
glioma7 / 10688365
head and neck tumor2 / 13630214
kidney tumor1 / 6895914
leukemia3 / 9584231
liver tumor1 / 9635910
lung tumor4 / 10312738
lymphoma1 / 7175513
non-neoplasia0 / 972500 
normal107 / 336030731
ovarian tumor0 / 766820 
pancreatic tumor1 / 1046169
primitive neuroectodermal tumor of the CNS3 / 12568023
prostate cancer3 / 10268029
retinoblastoma0 / 463560 
skin tumor6 / 12494948
soft tissue/muscle tissue tumor3 / 12519123
uterine tumor3 / 9025733
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland1 / 3319730
ascites4 / 4001599
bladder0 / 297570 
blood3 / 12347824
bone3 / 7165541
bone marrow0 / 488010 
brain39 / 110098935
cervix3 / 4817162
connective tissue3 / 14925520
ear0 / 162120 
embryonic tissue13 / 21572260
esophagus0 / 202090 
eye10 / 21105447
heart3 / 8962633
intestine9 / 23447238
kidney10 / 21177747
larynx0 / 241450 
liver1 / 2077434
lung14 / 33697441
lymph1 / 4427022
lymph node0 / 916100 
mammary gland12 / 15327178
mouth2 / 6705229
muscle1 / 1077159
nerve2 / 15768126
ovary2 / 10205119
pancreas1 / 2148124
parathyroid0 / 205390 
pharynx0 / 413280 
pituitary gland0 / 165850 
placenta4 / 28082514
prostate6 / 18934531
salivary gland0 / 201550 
skin8 / 21057437
spleen1 / 5395218
stomach4 / 9661941
testis10 / 33044230
thymus0 / 811310 
thyroid2 / 4747342
tonsil0 / 169990 
trachea1 / 5241319
umbilical cord0 / 136800 
uterus4 / 23287817
vascular0 / 517800 
Microarray in BioGPS Top
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: A_24_P380861
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala2.69 ± 1.08
Basal Forebrain2.15 ± 0.25
Basal Part of Pons3.06 ± 0.67
Cerebellar Cortex3.39 ± 0.47
Cerebellar Nuclei2.54 ± 0.63
Claustrum2.7 ± 0.75
Epithalamus2.63 ± 0.67
Frontal Lobe2.56 ± 0.8
Globus Pallidus2.27 ± 0.52
Hypothalamus2.48 ± 0.54
Insula2.7 ± 0.81
Limbic Lobe2.44 ± 0.82
Mesencephalon2.77 ± 0.79
Myelencephalon2.56 ± 0.8
Occipital Lobe2.77 ± 0.74
Parietal Lobe2.81 ± 0.68
Pontine Tegmentum2.52 ± 0.8
Striatum2.34 ± 0.88
Subthalamus2.43 ± 0.99
Temporal Lobe2.36 ± 0.77
Thalamus2.68 ± 0.65
White Matter3.89 ± 0.31
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Anks6CBCerebellum5.92
7.29
Anks6CTXCerebral cortex3.76
3.27
Anks6HIPHippocampal region6.41
6.24
Anks6HPFHippocampal formation5.28
4.86
Anks6HYHypothalamus3.3
4.24
Anks6LSXLateral septal complex0.69
0.48
Anks6MBMidbrain1.44
1.54
Anks6MYMedulla5.09
4.54
Anks6OLFOlfactory bulb5.36
4.42
Anks6PPons3.03
2.98
Anks6PALPallidum0.91
1.06
Anks6RHPRetrohippocampal region3.43
2.94
Anks6sAMYStriatum-like amygdalar nuclei0.6
0.82
Anks6STRStriatum1.23
1.22
Anks6STRdStriatum dorsal region1.17
1.25
Anks6STRvStriatum ventral region1.89
1.53
Anks6THThalamus1.36
1.39
Peptide Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018