AutismKB 2.0

Annotation Detail for EPHA7


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Basic Information Top
Gene Symbol:EPHA7 ( EHK3,HEK11 )
Gene Full Name: EPH receptor A7
Band: 6q16.1
Quick LinksEntrez ID:2045; OMIM: 602190; Uniprot ID:EPHA7_HUMAN; ENSEMBL ID: ENSG00000135333; HGNC ID: 3390
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body4 / 7076156
blastocyst3 / 6231948
fetus29 / 56401251
neonate0 / 310970 
infant0 / 236200 
juvenile0 / 555560 
adult22 / 193912111
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma0 / 174750 
breast (mammary gland) tumor0 / 941780 
cervical tumor0 / 343660 
chondrosarcoma1 / 8282312
colorectal tumor0 / 1142460 
esophageal tumor0 / 172900 
gastrointestinal tumor8 / 11936967
germ cell tumor3 / 26384511
glioma0 / 1068830 
head and neck tumor0 / 1363020 
kidney tumor0 / 689590 
leukemia0 / 958420 
liver tumor2 / 9635920
lung tumor0 / 1031270 
lymphoma0 / 717550 
non-neoplasia1 / 9725010
normal61 / 336030718
ovarian tumor0 / 766820 
pancreatic tumor0 / 1046160 
primitive neuroectodermal tumor of the CNS0 / 1256800 
prostate cancer0 / 1026800 
retinoblastoma0 / 463560 
skin tumor0 / 1249490 
soft tissue/muscle tissue tumor0 / 1251910 
uterine tumor2 / 9025722
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland0 / 331970 
ascites0 / 400150 
bladder0 / 297570 
blood0 / 1234780 
bone1 / 7165513
bone marrow0 / 488010 
brain20 / 110098918
cervix0 / 481710 
connective tissue0 / 1492550 
ear2 / 16212123
embryonic tissue10 / 21572246
esophagus0 / 202090 
eye4 / 21105418
heart2 / 8962622
intestine9 / 23447238
kidney6 / 21177728
larynx0 / 241450 
liver2 / 2077439
lung1 / 3369742
lymph0 / 442700 
lymph node0 / 916100 
mammary gland2 / 15327113
mouth0 / 670520 
muscle2 / 10771518
nerve0 / 157680 
ovary0 / 1020510 
pancreas0 / 2148120 
parathyroid5 / 20539243
pharynx0 / 413280 
pituitary gland0 / 165850 
placenta0 / 2808250 
prostate2 / 18934510
salivary gland0 / 201550 
skin0 / 2105740 
spleen0 / 539520 
stomach1 / 9661910
testis4 / 33044212
thymus0 / 811310 
thyroid0 / 474730 
tonsil0 / 169990 
trachea0 / 524130 
umbilical cord0 / 136800 
uterus2 / 2328788
vascular1 / 5178019
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 206852_at
Cell line Expression level Expression bar
721_B_lymphoblasts7.5
Adipocyte6.7
AdrenalCortex9.3
Adrenalgland6.25
Amygdala6.85
Appendix8.25
AtrioventricularNode7.9
BDCA4+_DentriticCells6.75
Bonemarrow7.65
BronchialEpithelialCells6.55
CD105+_Endothelial6.8
CD14+_Monocytes7.4
CD19+_BCells(neg._sel.)7.1
CD33+_Myeloid8.5
CD34+8.2
CD4+_Tcells7.1
CD56+_NKCells7.65
CD71+_EarlyErythroid6.65
CD8+_Tcells6.1
CardiacMyocytes11.9
Caudatenucleus6.2
Cerebellum5.7
CerebellumPeduncles8.5
CiliaryGanglion6.25
CingulateCortex7.3
Colorectaladenocarcinoma6.9
DorsalRootGanglion6.3
FetalThyroid7
Fetalbrain6.6
Fetalliver6.2
Fetallung5.25
GlobusPallidus5.6
Heart11.3
Hypothalamus7.1
Kidney6.85
Leukemia_chronicMyelogenousK-5626.2
Leukemia_promyelocytic-HL-606.15
Leukemialymphoblastic(MOLT-4)5.3
Liver10.65
Lung7.5
Lymphnode5.65
Lymphoma_burkitts(Daudi)9.25
Lymphoma_burkitts(Raji)10.85
MedullaOblongata6.15
OccipitalLobe6.15
OlfactoryBulb5.35
Ovary5.45
Pancreas5.95
PancreaticIslet7.55
ParietalLobe7.95
Pituitary8.05
Placenta6.75
Pons6.95
PrefrontalCortex8.05
Prostate7.85
Salivarygland5.9
SkeletalMuscle10.3
Skin7.7
SmoothMuscle7.75
Spinalcord7.3
SubthalamicNucleus6.75
SuperiorCervicalGanglion11.35
TemporalLobe6.55
Testis5.9
TestisGermCell5.45
TestisIntersitial6.3
TestisLeydigCell7.25
TestisSeminiferousTubule6
Thalamus7.25
Thymus5.15
Thyroid8.2
Tongue9.55
Tonsil6.9
Trachea5.75
TrigeminalGanglion9.2
Uterus5.4
UterusCorpus7.05
WholeBlood7.5
Wholebrain5.4
colon6.85
pineal_day8.6
pineal_night8.32
retina8.35
small_intestine6.55
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: A_24_P226332
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala4.51 ± 0.7
Basal Forebrain4.17 ± 0.47
Basal Part of Pons4.73 ± 0.44
Cerebellar Cortex4.37 ± 0.48
Cerebellar Nuclei4.27 ± 0.73
Claustrum3.54 ± 0.89
Epithalamus3.48 ± 0.72
Frontal Lobe4.03 ± 0.74
Globus Pallidus3.39 ± 0.5
Hypothalamus3.86 ± 0.82
Insula3.97 ± 0.68
Limbic Lobe4.82 ± 0.86
Mesencephalon4.42 ± 0.71
Myelencephalon4.13 ± 0.67
Occipital Lobe4.81 ± 0.72
Parietal Lobe4.33 ± 0.6
Pontine Tegmentum3.93 ± 0.85
Striatum5.35 ± 0.57
Subthalamus4.82 ± 0.25
Temporal Lobe4.07 ± 0.64
Thalamus3.54 ± 0.86
White Matter1.81 ± 0.7
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Epha7CBCerebellum4.24
5.67
Epha7CTXCerebral cortex7.45
5.69
Epha7HIPHippocampal region40.7
56.98
Epha7HPFHippocampal formation30.04
36.87
Epha7HYHypothalamus1.38
0.87
Epha7LSXLateral septal complex8.98
6.37
Epha7MBMidbrain2.32
2.28
Epha7MYMedulla1.32
1.01
Epha7OLFOlfactory bulb16.3
12.18
Epha7PPons0.87
0.67
Epha7PALPallidum1.55
1.05
Epha7RHPRetrohippocampal region12.99
11
Epha7sAMYStriatum-like amygdalar nuclei1.58
1.07
Epha7STRStriatum4.26
2.69
Epha7STRdStriatum dorsal region2.86
1.73
Epha7STRvStriatum ventral region8.71
5.06
Epha7THThalamus6.55
6.69
Peptide Top
Peptide Name Peptide Lengh Peptide Start Peptide End Peptide Sequence Source
PAp00039741 14 296 309 CPTHSFSDKEGSSR Peptide Atlas

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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