Annotation Detail for EPHB2
Basic Information Top
| Gene Symbol: | EPHB2 ( CAPB,DRT,EK5,EPHT3,ERK,Hek5,MGC87492,PCBC,Tyro5 ) |
|---|---|
| Gene Full Name: | EPH receptor B2 |
| Band: | 1p36.12 |
| Quick Links | Entrez ID:2048; OMIM: 600997; Uniprot ID:EPHB2_HUMAN; ENSEMBL ID: ENSG00000133216; HGNC ID: 3393 |
| Relate to Another Database: | SFARIGene; denovo-db |
- Unigene ID: Hs.523329
| Pool Name | Gene EST/Total EST in pool | Transcripts per million(TPM) | Bar based on TPM |
|---|---|---|---|
 | |||
| embryoid body | 3 / 70761 | 42 |  |
| blastocyst | 3 / 62319 | 48 | |
| fetus | 25 / 564012 | 44 | |
| neonate | 2 / 31097 | 64 |  |
| infant | 0 / 23620 | 0 | |
| juvenile | 0 / 55556 | 0 | |
| adult | 57 / 1939121 | 29 | |
| Pool Name | Gene EST/Total EST in pool | Transcripts per million(TPM) | Bar based on TPM |
|---|---|---|---|
| |||
| adrenal tumor | 0 / 12794 | 0 | |
| bladder carcinoma | 0 / 17475 | 0 | |
| breast (mammary gland) tumor | 1 / 94178 | 10 |  |
| cervical tumor | 0 / 34366 | 0 | |
| chondrosarcoma | 6 / 82823 | 72 | |
| colorectal tumor | 18 / 114246 | 157 | |
| esophageal tumor | 0 / 17290 | 0 | |
| gastrointestinal tumor | 4 / 119369 | 33 | |
| germ cell tumor | 5 / 263845 | 18 | |
| glioma | 4 / 106883 | 37 | |
| head and neck tumor | 2 / 136302 | 14 | |
| kidney tumor | 1 / 68959 | 14 | |
| leukemia | 0 / 95842 | 0 | |
| liver tumor | 1 / 96359 | 10 | |
| lung tumor | 5 / 103127 | 48 | |
| lymphoma | 0 / 71755 | 0 | |
| non-neoplasia | 1 / 97250 | 10 | |
| normal | 64 / 3360307 | 19 | |
| ovarian tumor | 2 / 76682 | 26 | |
| pancreatic tumor | 1 / 104616 | 9 | |
| primitive neuroectodermal tumor of the CNS | 8 / 125680 | 63 | |
| prostate cancer | 0 / 102680 | 0 | |
| retinoblastoma | 1 / 46356 | 21 | |
| skin tumor | 1 / 124949 | 8 | |
| soft tissue/muscle tissue tumor | 2 / 125191 | 15 | |
| uterine tumor | 0 / 90257 | 0 |
| Pool Name | Gene EST/Total EST in pool | Transcripts per million(TPM) | Bar based on TPM |
|---|---|---|---|
| |||
| adipose tissue | 1 / 13106 | 76 | |
| adrenal gland | 0 / 33197 | 0 | |
| ascites | 0 / 40015 | 0 | |
| bladder | 0 / 29757 | 0 | |
| blood | 0 / 123478 | 0 | |
| bone | 5 / 71655 | 69 | |
| bone marrow | 0 / 48801 | 0 | |
| brain | 27 / 1100989 | 24 | |
| cervix | 0 / 48171 | 0 | |
| connective tissue | 2 / 149255 | 13 | |
| ear | 0 / 16212 | 0 | |
| embryonic tissue | 8 / 215722 | 37 | |
| esophagus | 0 / 20209 | 0 | |
| eye | 16 / 211054 | 75 | |
| heart | 6 / 89626 | 66 | |
| intestine | 31 / 234472 | 132 | |
| kidney | 6 / 211777 | 28 | |
| larynx | 1 / 24145 | 41 | |
| liver | 2 / 207743 | 9 | |
| lung | 14 / 336974 | 41 | |
| lymph | 0 / 44270 | 0 | |
| lymph node | 0 / 91610 | 0 | |
| mammary gland | 5 / 153271 | 32 | |
| mouth | 1 / 67052 | 14 | |
| muscle | 5 / 107715 | 46 | |
| nerve | 0 / 15768 | 0 | |
| ovary | 5 / 102051 | 48 | |
| pancreas | 1 / 214812 | 4 | |
| parathyroid | 0 / 20539 | 0 | |
| pharynx | 0 / 41328 | 0 | |
| pituitary gland | 0 / 16585 | 0 | |
| placenta | 5 / 280825 | 17 | |
| prostate | 0 / 189345 | 0 | |
| salivary gland | 0 / 20155 | 0 | |
| skin | 1 / 210574 | 4 | |
| spleen | 0 / 53952 | 0 | |
| stomach | 4 / 96619 | 41 | |
| testis | 2 / 330442 | 6 | |
| thymus | 0 / 81131 | 0 | |
| thyroid | 0 / 47473 | 0 | |
| tonsil | 0 / 16999 | 0 | |
| trachea | 0 / 52413 | 0 | |
| umbilical cord | 2 / 13680 | 146 | |
| uterus | 1 / 232878 | 4 | |
| vascular | 0 / 51780 | 0 |
- Microarray Platform: GeneAtlas U133A, gcrma
- Affymatrix Probe ID: 211165_x_at
| Cell line | Expression level | Expression bar |
|---|---|---|
| ||
| 721_B_lymphoblasts | 5.3 | |
| Adipocyte | 4.3 | |
| AdrenalCortex | 4.65 | |
| Adrenalgland | 3.7 | |
| Amygdala | 4.5 | |
| Appendix | 4.4 | |
| AtrioventricularNode | 3.45 | |
| BDCA4+_DentriticCells | 4.5 | |
| Bonemarrow | 4.25 | |
| BronchialEpithelialCells | 4.3 | |
| CD105+_Endothelial | 4.3 | |
| CD14+_Monocytes | 4.55 | |
| CD19+_BCells(neg._sel.) | 4.55 | |
| CD33+_Myeloid | 5.5 | |
| CD34+ | 5.25 | |
| CD4+_Tcells | 4.65 | |
| CD56+_NKCells | 5.05 | |
| CD71+_EarlyErythroid | 4 | |
| CD8+_Tcells | 4.1 | |
| CardiacMyocytes | 5.9 | |
| Caudatenucleus | 3.9 | |
| Cerebellum | 3.55 | |
| CerebellumPeduncles | 4.85 | |
| CiliaryGanglion | 3.05 | |
| CingulateCortex | 4.45 | |
| Colorectaladenocarcinoma | 4.3 | |
| DorsalRootGanglion | 3.4 | |
| FetalThyroid | 4.2 | |
| Fetalbrain | 4.4 | |
| Fetalliver | 3.8 | |
| Fetallung | 3.5 | |
| GlobusPallidus | 3.25 | |
| Heart | 5.7 | |
| Hypothalamus | 4.7 | |
| Kidney | 3.65 | |
| Leukemia_chronicMyelogenousK-562 | 3.9 | |
| Leukemia_promyelocytic-HL-60 | 3.85 | |
| Leukemialymphoblastic(MOLT-4) | 3.45 | |
| Liver | 5.75 | |
| Lung | 4.8 | |
| Lymphnode | 3.75 | |
| Lymphoma_burkitts(Daudi) | 5.5 | |
| Lymphoma_burkitts(Raji) | 6.1 | |
| MedullaOblongata | 3.9 | |
| OccipitalLobe | 3.9 | |
| OlfactoryBulb | 4.45 | |
| Ovary | 2.9 | |
| Pancreas | 4 | |
| PancreaticIslet | 4.65 | |
| ParietalLobe | 4.6 | |
| Pituitary | 5.3 | |
| Placenta | 21.1 | |
| Pons | 4.15 | |
| PrefrontalCortex | 5.5 | |
| Prostate | 4.95 | |
| Salivarygland | 3.5 | |
| SkeletalMuscle | 5.25 | |
| Skin | 3.5 | |
| SmoothMuscle | 4.95 | |
| Spinalcord | 4.65 | |
| SubthalamicNucleus | 4 | |
| SuperiorCervicalGanglion | 5 | |
| TemporalLobe | 3.95 | |
| Testis | 3.7 | |
| TestisGermCell | 3.65 | |
| TestisIntersitial | 3.55 | |
| TestisLeydigCell | 4.25 | |
| TestisSeminiferousTubule | 3.7 | |
| Thalamus | 4.45 | |
| Thymus | 3.35 | |
| Thyroid | 5.45 | |
| Tongue | 4.25 | |
| Tonsil | 4.2 | |
| Trachea | 3.65 | |
| TrigeminalGanglion | 4.45 | |
| Uterus | 3.5 | |
| UterusCorpus | 4.75 | |
| WholeBlood | 4.65 | |
| Wholebrain | 3.65 | |
| colon | 19.95 | |
| pineal_day | 5.34 | |
| pineal_night | 5.26 | |
| retina | 5.2 | |
| small_intestine | 15.05 | |
- Probe name: CUST_14148_PI416261804
- Donor H0351.2001
- Sex: Male Age: 24 years Race/Ethnicity: African American Handedness: Left
- Tissue Receipt Date: 7/29/2009 Serology: Pass Tissue pH :6.72 Additional Medical Information :History of asthma
- Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
- Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
| Tissue | Expression(mean ± stddev) | Expression Bar |
|---|---|---|
| Amygdala | 6.79 ± 0.45 | ![](../"images/bar_3.png"){kind=small}   |
| Basal Forebrain | 6.58 ± 0.2 | |
| Basal Part of Pons | 6.47 ± 0.52 | |
| Cerebellar Cortex | 6.37 ± 0.23 | |
| Cerebellar Nuclei | 6.9 ± 0.41 | |
| Claustrum | 7.31 ± 0.53 | |
| Epithalamus | 5.84 ± 0.9 | |
| Frontal Lobe | 6.97 ± 0.45 | |
| Globus Pallidus | 7.23 ± 0.26 | |
| Hypothalamus | 7.07 ± 0.42 | |
| Insula | 6.84 ± 0.54 | |
| Limbic Lobe | 7.14 ± 0.45 | |
| Mesencephalon | 7.09 ± 0.48 | |
| Myelencephalon | 6.83 ± 0.57 | |
| Occipital Lobe | 6.98 ± 0.57 | |
| Parietal Lobe | 6.95 ± 0.46 | |
| Pontine Tegmentum | 6.83 ± 0.45 | |
| Striatum | 6.78 ± 0.57 | |
| Subthalamus | 6.87 ± 0.14 | |
| Temporal Lobe | 6.77 ± 0.38 | |
| Thalamus | 6.38 ± 0.42 | |
| White Matter | 8.46 ± 0.43 | |
Mouse Brain ISH 
| Gene Symbol | Brain Structure ID | Brain Structure Name | Express Desity/Level (Meatured by ISH) | Express Bar |
|---|---|---|---|---|
| Ephb2 | CB | Cerebellum | 18.36 | |
| 19.56 | | |||
| Ephb2 | CTX | Cerebral cortex | 39.51 | |
| 27.64 | | |||
| Ephb2 | HIP | Hippocampal region | 24.75 | |
| 31.84 | | |||
| Ephb2 | HPF | Hippocampal formation | 27.22 | |
| 27.8 | | |||
| Ephb2 | HY | Hypothalamus | 22.16 | |
| 16.15 | | |||
| Ephb2 | LSX | Lateral septal complex | 2.35 | |
| 1.59 | | |||
| Ephb2 | MB | Midbrain | 24.65 | |
| 21.39 | | |||
| Ephb2 | MY | Medulla | 32.35 | |
| 34.65 | | |||
| Ephb2 | OLF | Olfactory bulb | 14.82 | |
| 10.89 | | |||
| Ephb2 | P | Pons | 27.15 | |
| 26.43 | | |||
| Ephb2 | PAL | Pallidum | 24.48 | |
| 21.83 | | |||
| Ephb2 | RHP | Retrohippocampal region | 32.67 | |
| 23.03 | | |||
| Ephb2 | sAMY | Striatum-like amygdalar nuclei | 18.35 | |
| 11.85 | | |||
| Ephb2 | STR | Striatum | 12.34 | |
| 8.3 | | |||
| Ephb2 | STRd | Striatum dorsal region | 13.41 | |
| 9.3 | | |||
| Ephb2 | STRv | Striatum ventral region | 10.86 | |
| 6.82 | | |||
| Ephb2 | TH | Thalamus | 28.35 | |
| 22.06 | |
| Peptide Name | Peptide Lengh | Peptide Start | Peptide End | Peptide Sequence | Source |
|---|---|---|---|---|---|
| EPHB2_HUMAN_581 | 14 | 581 | 594 | LQHYTSGHMTPGMK | PRIDE |
| PAp00082100 | 15 | 349 | 363 | DSGGREDLVYNIICK | Peptide Atlas |