AutismKB 2.0

Annotation Detail for EPHX2


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Basic Information Top
Gene Symbol:EPHX2 ( CEH,SEH )
Gene Full Name: epoxide hydrolase 2, cytoplasmic
Band: 8p21.2-p21.1
Quick LinksEntrez ID:2053; OMIM: 132811; Uniprot ID:HYES_HUMAN; ENSEMBL ID: ENSG00000120915; HGNC ID: 3402
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body1 / 7076114
blastocyst2 / 6231932
fetus22 / 56401239
neonate0 / 310970 
infant0 / 236200 
juvenile2 / 5555635
adult93 / 193912147
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma0 / 174750 
breast (mammary gland) tumor2 / 9417821
cervical tumor0 / 343660 
chondrosarcoma1 / 8282312
colorectal tumor10 / 11424687
esophageal tumor1 / 1729057
gastrointestinal tumor5 / 11936941
germ cell tumor14 / 26384553
glioma4 / 10688337
head and neck tumor5 / 13630236
kidney tumor5 / 6895972
leukemia7 / 9584273
liver tumor12 / 96359124
lung tumor4 / 10312738
lymphoma7 / 7175597
non-neoplasia3 / 9725030
normal233 / 336030769
ovarian tumor3 / 7668239
pancreatic tumor3 / 10461628
primitive neuroectodermal tumor of the CNS12 / 12568095
prostate cancer12 / 102680116
retinoblastoma3 / 4635664
skin tumor0 / 1249490 
soft tissue/muscle tissue tumor3 / 12519123
uterine tumor0 / 902570 
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue1 / 1310676
adrenal gland8 / 33197240
ascites1 / 4001524
bladder1 / 2975733
blood3 / 12347824
bone2 / 7165527
bone marrow5 / 48801102
brain57 / 110098951
cervix0 / 481710 
connective tissue3 / 14925520
ear0 / 162120 
embryonic tissue3 / 21572213
esophagus2 / 2020998
eye14 / 21105466
heart8 / 8962689
intestine31 / 234472132
kidney58 / 211777273
larynx3 / 24145124
liver25 / 207743120
lung15 / 33697444
lymph0 / 442700 
lymph node0 / 916100 
mammary gland8 / 15327152
mouth4 / 6705259
muscle1 / 1077159
nerve0 / 157680 
ovary3 / 10205129
pancreas8 / 21481237
parathyroid2 / 2053997
pharynx0 / 413280 
pituitary gland0 / 165850 
placenta10 / 28082535
prostate35 / 189345184
salivary gland1 / 2015549
skin1 / 2105744
spleen2 / 5395237
stomach6 / 9661962
testis14 / 33044242
thymus35 / 81131431
thyroid1 / 4747321
tonsil4 / 16999235
trachea3 / 5241357
umbilical cord0 / 136800 
uterus14 / 23287860
vascular0 / 517800 
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 209368_at
Cell line Expression level Expression bar
721_B_lymphoblasts5.85
Adipocyte5.25
AdrenalCortex5.8
Adrenalgland10.75
Amygdala5.4
Appendix5.35
AtrioventricularNode4
BDCA4+_DentriticCells5.05
Bonemarrow5.5
BronchialEpithelialCells5.2
CD105+_Endothelial5.05
CD14+_Monocytes5.4
CD19+_BCells(neg._sel.)5.25
CD33+_Myeloid5.95
CD34+6.65
CD4+_Tcells12.45
CD56+_NKCells5.75
CD71+_EarlyErythroid5.1
CD8+_Tcells13.35
CardiacMyocytes6.35
Caudatenucleus4.8
Cerebellum4.3
CerebellumPeduncles6.15
CiliaryGanglion3.9
CingulateCortex5.4
Colorectaladenocarcinoma6.9
DorsalRootGanglion4
FetalThyroid5.2
Fetalbrain4.3
Fetalliver16.05
Fetallung5.9
GlobusPallidus3.85
Heart9.35
Hypothalamus6.7
Kidney90.6
Leukemia_chronicMyelogenousK-56224.75
Leukemia_promyelocytic-HL-604.5
Leukemialymphoblastic(MOLT-4)4.1
Liver241.8
Lung6.05
Lymphnode5.15
Lymphoma_burkitts(Daudi)6.6
Lymphoma_burkitts(Raji)6.95
MedullaOblongata4.85
OccipitalLobe4.7
OlfactoryBulb4.05
Ovary3.5
Pancreas5.25
PancreaticIslet7.6
ParietalLobe5.5
Pituitary7.1
Placenta5.2
Pons5
PrefrontalCortex6.5
Prostate23.75
Salivarygland4.3
SkeletalMuscle6.35
Skin4
SmoothMuscle5.8
Spinalcord5.75
SubthalamicNucleus4.35
SuperiorCervicalGanglion5.95
TemporalLobe4.8
Testis4.55
TestisGermCell4.4
TestisIntersitial4.45
TestisLeydigCell5.2
TestisSeminiferousTubule4.45
Thalamus5.5
Thymus53.15
Thyroid10.2
Tongue5.3
Tonsil5.35
Trachea4.4
TrigeminalGanglion5.15
Uterus4.35
UterusCorpus4.75
WholeBlood5.65
Wholebrain4.45
colon6
pineal_day32.58
pineal_night29.24
retina10.275
small_intestine40.65
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: CUST_16289_PI416261804
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala3.82 ± 0.48
Basal Forebrain4.38 ± 0.23
Basal Part of Pons3.18 ± 0.56
Cerebellar Cortex3.91 ± 0.44
Cerebellar Nuclei3.34 ± 0.58
Claustrum3.47 ± 0.66
Epithalamus5.37 ± 0.63
Frontal Lobe3.82 ± 0.59
Globus Pallidus5.01 ± 0.57
Hypothalamus4.48 ± 0.75
Insula3.84 ± 0.54
Limbic Lobe3.61 ± 0.57
Mesencephalon4.22 ± 0.58
Myelencephalon4.01 ± 0.68
Occipital Lobe3.89 ± 0.55
Parietal Lobe3.87 ± 0.7
Pontine Tegmentum4.06 ± 0.51
Striatum4.71 ± 0.71
Subthalamus3.86 ± 0.66
Temporal Lobe3.72 ± 0.54
Thalamus4.19 ± 0.5
White Matter4.72 ± 0.43
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Ephx2CBCerebellum4.81
5.37
Ephx2CTXCerebral cortex2.24
1.69
Ephx2HIPHippocampal region4.45
4.22
Ephx2HPFHippocampal formation4.82
4.27
Ephx2HYHypothalamus0.47
0.39
Ephx2LSXLateral septal complex0.92
0.94
Ephx2MBMidbrain0.92
1.17
Ephx2MYMedulla3.87
4.34
Ephx2OLFOlfactory bulb5.6
4.08
Ephx2PPons1.22
1.35
Ephx2PALPallidum0.59
0.49
Ephx2RHPRetrohippocampal region5.17
4.11
Ephx2sAMYStriatum-like amygdalar nuclei5.31
3.87
Ephx2STRStriatum1.13
0.89
Ephx2STRdStriatum dorsal region0.49
0.47
Ephx2STRvStriatum ventral region1.47
0.94
Ephx2THThalamus1.13
1.05
Peptide Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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