AutismKB 2.0

Annotation Detail for C3orf58


View Evidences View Variants View Annotations
Basic Information Top
Gene Symbol:C3orf58 ( DIA1,MGC33365 )
Gene Full Name: chromosome 3 open reading frame 58
Band: 3q24
Quick LinksEntrez ID:205428; OMIM: 612200; Uniprot ID:CC058_HUMAN; ENSEMBL ID: ENSG00000181744; HGNC ID: 28490
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body3 / 7076142
blastocyst2 / 6231932
fetus25 / 56401244
neonate0 / 310970 
infant0 / 236200 
juvenile0 / 555560 
adult62 / 193912131
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma0 / 174750 
breast (mammary gland) tumor1 / 9417810
cervical tumor1 / 3436629
chondrosarcoma1 / 8282312
colorectal tumor0 / 1142460 
esophageal tumor0 / 172900 
gastrointestinal tumor1 / 1193698
germ cell tumor4 / 26384515
glioma3 / 10688328
head and neck tumor16 / 136302117
kidney tumor3 / 6895943
leukemia2 / 9584220
liver tumor1 / 9635910
lung tumor0 / 1031270 
lymphoma0 / 717550 
non-neoplasia3 / 9725030
normal110 / 336030732
ovarian tumor5 / 7668265
pancreatic tumor0 / 1046160 
primitive neuroectodermal tumor of the CNS0 / 1256800 
prostate cancer3 / 10268029
retinoblastoma2 / 4635643
skin tumor1 / 1249498
soft tissue/muscle tissue tumor0 / 1251910 
uterine tumor1 / 9025711
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland0 / 331970 
ascites0 / 400150 
bladder0 / 297570 
blood0 / 1234780 
bone1 / 7165513
bone marrow4 / 4880181
brain66 / 110098959
cervix2 / 4817141
connective tissue1 / 1492556
ear2 / 16212123
embryonic tissue5 / 21572223
esophagus0 / 202090 
eye8 / 21105437
heart3 / 8962633
intestine4 / 23447217
kidney12 / 21177756
larynx1 / 2414541
liver4 / 20774319
lung6 / 33697417
lymph0 / 442700 
lymph node7 / 9161076
mammary gland20 / 153271130
mouth15 / 67052223
muscle1 / 1077159
nerve0 / 157680 
ovary7 / 10205168
pancreas1 / 2148124
parathyroid1 / 2053948
pharynx0 / 413280 
pituitary gland0 / 165850 
placenta12 / 28082542
prostate4 / 18934521
salivary gland0 / 201550 
skin1 / 2105744
spleen0 / 539520 
stomach1 / 9661910
testis13 / 33044239
thymus3 / 8113136
thyroid0 / 474730 
tonsil0 / 169990 
trachea2 / 5241338
umbilical cord0 / 136800 
uterus3 / 23287812
vascular7 / 51780135
Microarray in BioGPS Top
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: A_23_P144134
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala6.19 ± 0.79
Basal Forebrain6.98 ± 0.49
Basal Part of Pons6.41 ± 0.57
Cerebellar Cortex6.9 ± 0.18
Cerebellar Nuclei6.59 ± 0.45
Claustrum6.35 ± 1.01
Epithalamus7.13 ± 0.91
Frontal Lobe6.18 ± 0.51
Globus Pallidus6.43 ± 0.55
Hypothalamus6.67 ± 0.56
Insula6.12 ± 0.39
Limbic Lobe5.77 ± 0.6
Mesencephalon6.35 ± 0.64
Myelencephalon6.33 ± 0.61
Occipital Lobe7.06 ± 0.51
Parietal Lobe6.38 ± 0.51
Pontine Tegmentum6.36 ± 0.48
Striatum5.35 ± 0.57
Subthalamus6.81 ± 0.74
Temporal Lobe6.33 ± 0.51
Thalamus6.19 ± 0.56
White Matter8.09 ± 0.22
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
1190002N15RikCBCerebellum23.37
62.27
1190002N15RikCTXCerebral cortex5.17
4.65
1190002N15RikHIPHippocampal region2.04
2.01
1190002N15RikHPFHippocampal formation1.55
1.47
1190002N15RikHYHypothalamus0.15
0.17
1190002N15RikLSXLateral septal complex0.19
0.11
1190002N15RikMBMidbrain1.23
1.45
1190002N15RikMYMedulla3.42
4.72
1190002N15RikOLFOlfactory bulb6.25
4.78
1190002N15RikPPons1.9
2.76
1190002N15RikPALPallidum0.52
1
1190002N15RikRHPRetrohippocampal region0.78
0.76
1190002N15RiksAMYStriatum-like amygdalar nuclei0.23
0.21
1190002N15RikSTRStriatum0.46
0.48
1190002N15RikSTRdStriatum dorsal region0.62
0.69
1190002N15RikSTRvStriatum ventral region0.22
0.2
1190002N15RikTHThalamus0.35
0.56
Peptide Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018