AutismKB 2.0

Annotation Detail for DHRSX


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Basic Information Top
Gene Symbol:DHRSX ( CXorf11,DHRS5X,DHRS5Y,DHRSXY,DHRSY,SDR46C1 )
Gene Full Name: dehydrogenase/reductase (SDR family) X-linked
Band: Xp22.33 and Yp11.2
Quick LinksEntrez ID:207063; OMIM: NA; Uniprot ID:DHRSX_HUMAN; ENSEMBL ID: ENSG00000169084; HGNC ID: 18399
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body5 / 7076170
blastocyst4 / 6231964
fetus26 / 56401246
neonate0 / 310970 
infant0 / 236200 
juvenile2 / 5555635
adult137 / 193912170
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor1 / 1279478
bladder carcinoma0 / 174750 
breast (mammary gland) tumor3 / 9417831
cervical tumor3 / 3436687
chondrosarcoma10 / 82823120
colorectal tumor9 / 11424678
esophageal tumor0 / 172900 
gastrointestinal tumor11 / 11936992
germ cell tumor17 / 26384564
glioma8 / 10688374
head and neck tumor13 / 13630295
kidney tumor4 / 6895958
leukemia6 / 9584262
liver tumor0 / 963590 
lung tumor5 / 10312748
lymphoma2 / 7175527
non-neoplasia3 / 9725030
normal164 / 336030748
ovarian tumor3 / 7668239
pancreatic tumor60 / 104616573
primitive neuroectodermal tumor of the CNS3 / 12568023
prostate cancer22 / 102680214
retinoblastoma3 / 4635664
skin tumor1 / 1249498
soft tissue/muscle tissue tumor9 / 12519171
uterine tumor5 / 9025755
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue2 / 13106152
adrenal gland1 / 3319730
ascites5 / 40015124
bladder0 / 297570 
blood3 / 12347824
bone8 / 71655111
bone marrow2 / 4880140
brain30 / 110098927
cervix5 / 48171103
connective tissue8 / 14925553
ear0 / 162120 
embryonic tissue13 / 21572260
esophagus0 / 202090 
eye10 / 21105447
heart7 / 8962678
intestine18 / 23447276
kidney12 / 21177756
larynx1 / 2414541
liver5 / 20774324
lung31 / 33697491
lymph1 / 4427022
lymph node4 / 9161043
mammary gland3 / 15327119
mouth0 / 670520 
muscle8 / 10771574
nerve2 / 15768126
ovary2 / 10205119
pancreas61 / 214812283
parathyroid1 / 2053948
pharynx0 / 413280 
pituitary gland1 / 1658560
placenta18 / 28082564
prostate24 / 189345126
salivary gland11 / 20155545
skin8 / 21057437
spleen2 / 5395237
stomach8 / 9661982
testis17 / 33044251
thymus2 / 8113124
thyroid1 / 4747321
tonsil0 / 169990 
trachea1 / 5241319
umbilical cord0 / 136800 
uterus15 / 23287864
vascular2 / 5178038
Microarray in BioGPS Top
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: A_24_P378987
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala5.58 ± 0.45
Basal Forebrain5.92 ± 0.22
Basal Part of Pons5.38 ± 0.24
Cerebellar Cortex5.49 ± 0.17
Cerebellar Nuclei5.82 ± 0.27
Claustrum5.11 ± 0.48
Epithalamus6.37 ± 0.59
Frontal Lobe5.75 ± 0.34
Globus Pallidus6.75 ± 0.34
Hypothalamus5.82 ± 0.47
Insula5.61 ± 0.19
Limbic Lobe5.58 ± 0.34
Mesencephalon5.84 ± 0.38
Myelencephalon5.77 ± 0.42
Occipital Lobe5.82 ± 0.44
Parietal Lobe5.74 ± 0.33
Pontine Tegmentum5.91 ± 0.34
Striatum6.33 ± 0.31
Subthalamus5.7 ± 0.25
Temporal Lobe5.6 ± 0.28
Thalamus5.91 ± 0.38
White Matter5.99 ± 0.23
Mouse Brain ISH
Peptide Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018