AutismKB 2.0

Annotation Detail for ERF


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Basic Information Top
Gene Symbol:ERF ( PE-2,PE2 )
Gene Full Name: Ets2 repressor factor
Band: 19q13.2
Quick LinksEntrez ID:2077; OMIM: 611888; Uniprot ID:ERF_HUMAN; ENSEMBL ID: ENSG00000105722; HGNC ID: 3444
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body2 / 7076128
blastocyst5 / 6231980
fetus19 / 56401233
neonate1 / 3109732
infant0 / 236200 
juvenile3 / 5555653
adult53 / 193912127
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma0 / 174750 
breast (mammary gland) tumor5 / 9417853
cervical tumor0 / 343660 
chondrosarcoma4 / 8282348
colorectal tumor2 / 11424617
esophageal tumor0 / 172900 
gastrointestinal tumor7 / 11936958
germ cell tumor21 / 26384579
glioma13 / 106883121
head and neck tumor3 / 13630222
kidney tumor1 / 6895914
leukemia5 / 9584252
liver tumor2 / 9635920
lung tumor0 / 1031270 
lymphoma2 / 7175527
non-neoplasia2 / 9725020
normal93 / 336030727
ovarian tumor2 / 7668226
pancreatic tumor3 / 10461628
primitive neuroectodermal tumor of the CNS6 / 12568047
prostate cancer0 / 1026800 
retinoblastoma3 / 4635664
skin tumor5 / 12494940
soft tissue/muscle tissue tumor3 / 12519123
uterine tumor4 / 9025744
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland0 / 331970 
ascites2 / 4001549
bladder1 / 2975733
blood3 / 12347824
bone5 / 7165569
bone marrow2 / 4880140
brain28 / 110098925
cervix2 / 4817141
connective tissue1 / 1492556
ear0 / 162120 
embryonic tissue9 / 21572241
esophagus0 / 202090 
eye16 / 21105475
heart2 / 8962622
intestine9 / 23447238
kidney12 / 21177756
larynx0 / 241450 
liver2 / 2077439
lung6 / 33697417
lymph2 / 4427045
lymph node1 / 9161010
mammary gland5 / 15327132
mouth0 / 670520 
muscle0 / 1077150 
nerve2 / 15768126
ovary3 / 10205129
pancreas7 / 21481232
parathyroid0 / 205390 
pharynx0 / 413280 
pituitary gland0 / 165850 
placenta4 / 28082514
prostate3 / 18934515
salivary gland1 / 2015549
skin6 / 21057428
spleen0 / 539520 
stomach4 / 9661941
testis8 / 33044224
thymus1 / 8113112
thyroid5 / 47473105
tonsil0 / 169990 
trachea0 / 524130 
umbilical cord1 / 1368073
uterus7 / 23287830
vascular2 / 5178038
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 203643_at
Cell line Expression level Expression bar
721_B_lymphoblasts36.55
Adipocyte21.35
AdrenalCortex26.85
Adrenalgland19.55
Amygdala21.9
Appendix22.9
AtrioventricularNode22.45
BDCA4+_DentriticCells21.35
Bonemarrow21.65
BronchialEpithelialCells21.8
CD105+_Endothelial22.05
CD14+_Monocytes24.9
CD19+_BCells(neg._sel.)33.2
CD33+_Myeloid27.2
CD34+27.65
CD4+_Tcells24.4
CD56+_NKCells26.8
CD71+_EarlyErythroid23.75
CD8+_Tcells21.45
CardiacMyocytes27.1
Caudatenucleus19.6
Cerebellum17.7
CerebellumPeduncles26.3
CiliaryGanglion32.8
CingulateCortex23.1
Colorectaladenocarcinoma29.65
DorsalRootGanglion19.05
FetalThyroid21.45
Fetalbrain21.3
Fetalliver18.75
Fetallung16.6
GlobusPallidus17.4
Heart37.3
Hypothalamus21.95
Kidney20.85
Leukemia_chronicMyelogenousK-56222.3
Leukemia_promyelocytic-HL-6018.95
Leukemialymphoblastic(MOLT-4)17.2
Liver49.5
Lung26.7
Lymphnode17.65
Lymphoma_burkitts(Daudi)28.8
Lymphoma_burkitts(Raji)31.7
MedullaOblongata20.55
OccipitalLobe19.35
OlfactoryBulb17.35
Ovary15.6
Pancreas18.15
PancreaticIslet23
ParietalLobe23.3
Pituitary29.55
Placenta22
Pons21.3
PrefrontalCortex27.4
Prostate29.8
Salivarygland18.35
SkeletalMuscle31.7
Skin18.95
SmoothMuscle26.7
Spinalcord23.05
SubthalamicNucleus20.75
SuperiorCervicalGanglion37.1
TemporalLobe20.95
Testis18.9
TestisGermCell18.05
TestisIntersitial17.75
TestisLeydigCell22.35
TestisSeminiferousTubule22.05
Thalamus22.35
Thymus25.6
Thyroid39.5
Tongue28.2
Tonsil21.35
Trachea21.2
TrigeminalGanglion24.85
Uterus17.95
UterusCorpus19.75
WholeBlood28.1
Wholebrain17.75
colon21.3
pineal_day25.82
pineal_night26
retina26.525
small_intestine20.85
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: CUST_4818_PI416261804
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala2.48 ± 1.1
Basal Forebrain2.39 ± 1.13
Basal Part of Pons1.69 ± 0.5
Cerebellar Cortex1.73 ± 0.74
Cerebellar Nuclei2.43 ± 0.69
Claustrum2.73 ± 0.85
Epithalamus1.61 ± 0.85
Frontal Lobe1.9 ± 0.91
Globus Pallidus2.43 ± 0.68
Hypothalamus2.09 ± 0.74
Insula1.89 ± 0.67
Limbic Lobe2 ± 0.74
Mesencephalon2.18 ± 0.72
Myelencephalon2.12 ± 0.75
Occipital Lobe2.01 ± 0.62
Parietal Lobe2.09 ± 0.83
Pontine Tegmentum2.06 ± 0.93
Striatum2.27 ± 0.74
Subthalamus2.43 ± 1.19
Temporal Lobe1.92 ± 0.77
Thalamus1.95 ± 0.7
White Matter2.34 ± 0.8
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
ErfCBCerebellum0
0
ErfCTXCerebral cortex0
0
ErfHIPHippocampal region0
0
ErfHPFHippocampal formation0
0
ErfHYHypothalamus0
0
ErfLSXLateral septal complex0
0
ErfMBMidbrain0
0
ErfMYMedulla0
0
ErfOLFOlfactory bulb0
0
ErfPPons0
0
ErfPALPallidum0
0
ErfRHPRetrohippocampal region0
0
ErfsAMYStriatum-like amygdalar nuclei0
0
ErfSTRStriatum0
0
ErfSTRdStriatum dorsal region0
0
ErfSTRvStriatum ventral region0
0
ErfTHThalamus0
0
Peptide Top
Peptide Name Peptide Lengh Peptide Start Peptide End Peptide Sequence Source
PAp00000634 23 459 481 APPAPPKPEPGEAPGASQCMPLK Peptide Atlas

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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