Annotation Detail for ESR2
Basic Information Top
| Gene Symbol: | ESR2 ( ER-BETA,ESR-BETA,ESRB,ESTRB,Erb,NR3A2 ) |
|---|---|
| Gene Full Name: | estrogen receptor 2 (ER beta) |
| Band: | 14q23.2-q23.3 |
| Quick Links | Entrez ID:2100; OMIM: 601663; Uniprot ID:ESR2_HUMAN; ENSEMBL ID: ENSG00000140009; HGNC ID: 3468 |
| Relate to Another Database: | SFARIGene; denovo-db |
- Unigene ID: Hs.660607
| Pool Name | Gene EST/Total EST in pool | Transcripts per million(TPM) | Bar based on TPM |
|---|---|---|---|
 | |||
| embryoid body | 1 / 70761 | 14 |  |
| blastocyst | 1 / 62319 | 16 | |
| fetus | 1 / 564012 | 1 |  |
| neonate | 0 / 31097 | 0 | |
| infant | 0 / 23620 | 0 | |
| juvenile | 0 / 55556 | 0 | |
| adult | 2 / 1939121 | 1 | |
| Pool Name | Gene EST/Total EST in pool | Transcripts per million(TPM) | Bar based on TPM |
|---|---|---|---|
| |||
| adrenal tumor | 0 / 12794 | 0 | |
| bladder carcinoma | 0 / 17475 | 0 | |
| breast (mammary gland) tumor | 0 / 94178 | 0 | |
| cervical tumor | 0 / 34366 | 0 | |
| chondrosarcoma | 0 / 82823 | 0 | |
| colorectal tumor | 0 / 114246 | 0 | |
| esophageal tumor | 0 / 17290 | 0 | |
| gastrointestinal tumor | 0 / 119369 | 0 | |
| germ cell tumor | 4 / 263845 | 15 | |
| glioma | 0 / 106883 | 0 | |
| head and neck tumor | 0 / 136302 | 0 | |
| kidney tumor | 0 / 68959 | 0 | |
| leukemia | 0 / 95842 | 0 | |
| liver tumor | 0 / 96359 | 0 | |
| lung tumor | 1 / 103127 | 9 |  |
| lymphoma | 0 / 71755 | 0 | |
| non-neoplasia | 0 / 97250 | 0 | |
| normal | 10 / 3360307 | 2 | |
| ovarian tumor | 0 / 76682 | 0 | |
| pancreatic tumor | 0 / 104616 | 0 | |
| primitive neuroectodermal tumor of the CNS | 5 / 125680 | 39 | |
| prostate cancer | 0 / 102680 | 0 | |
| retinoblastoma | 0 / 46356 | 0 | |
| skin tumor | 0 / 124949 | 0 | |
| soft tissue/muscle tissue tumor | 0 / 125191 | 0 | |
| uterine tumor | 0 / 90257 | 0 |
| Pool Name | Gene EST/Total EST in pool | Transcripts per million(TPM) | Bar based on TPM |
|---|---|---|---|
| |||
| adipose tissue | 0 / 13106 | 0 | |
| adrenal gland | 0 / 33197 | 0 | |
| ascites | 0 / 40015 | 0 | |
| bladder | 0 / 29757 | 0 | |
| blood | 0 / 123478 | 0 | |
| bone | 0 / 71655 | 0 | |
| bone marrow | 0 / 48801 | 0 | |
| brain | 1 / 1100989 | 0 | |
| cervix | 0 / 48171 | 0 | |
| connective tissue | 0 / 149255 | 0 | |
| ear | 0 / 16212 | 0 | |
| embryonic tissue | 2 / 215722 | 9 | |
| esophagus | 0 / 20209 | 0 | |
| eye | 0 / 211054 | 0 | |
| heart | 0 / 89626 | 0 | |
| intestine | 0 / 234472 | 0 | |
| kidney | 0 / 211777 | 0 | |
| larynx | 0 / 24145 | 0 | |
| liver | 0 / 207743 | 0 | |
| lung | 2 / 336974 | 5 | |
| lymph | 0 / 44270 | 0 | |
| lymph node | 0 / 91610 | 0 | |
| mammary gland | 0 / 153271 | 0 | |
| mouth | 0 / 67052 | 0 | |
| muscle | 0 / 107715 | 0 | |
| nerve | 0 / 15768 | 0 | |
| ovary | 0 / 102051 | 0 | |
| pancreas | 0 / 214812 | 0 | |
| parathyroid | 0 / 20539 | 0 | |
| pharynx | 0 / 41328 | 0 | |
| pituitary gland | 0 / 16585 | 0 | |
| placenta | 0 / 280825 | 0 | |
| prostate | 0 / 189345 | 0 | |
| salivary gland | 0 / 20155 | 0 | |
| skin | 0 / 210574 | 0 | |
| spleen | 0 / 53952 | 0 | |
| stomach | 0 / 96619 | 0 | |
| testis | 10 / 330442 | 30 | |
| thymus | 0 / 81131 | 0 | |
| thyroid | 0 / 47473 | 0 | |
| tonsil | 0 / 16999 | 0 | |
| trachea | 0 / 52413 | 0 | |
| umbilical cord | 0 / 13680 | 0 | |
| uterus | 0 / 232878 | 0 | |
| vascular | 0 / 51780 | 0 |
- Microarray Platform: GeneAtlas U133A, gcrma
- Affymatrix Probe ID: 211118_x_at
| Cell line | Expression level | Expression bar |
|---|---|---|
| ||
| 721_B_lymphoblasts | 4.6 | |
| Adipocyte | 3.6 | |
| AdrenalCortex | 3.8 | |
| Adrenalgland | 3.1 | |
| Amygdala | 3.85 | |
| Appendix | 3.7 | |
| AtrioventricularNode | 2.9 | |
| BDCA4+_DentriticCells | 4.1 | |
| Bonemarrow | 3.7 | |
| BronchialEpithelialCells | 3.65 | |
| CD105+_Endothelial | 3.7 | |
| CD14+_Monocytes | 3.9 | |
| CD19+_BCells(neg._sel.) | 3.9 | |
| CD33+_Myeloid | 4.7 | |
| CD34+ | 4.7 | |
| CD4+_Tcells | 4.05 | |
| CD56+_NKCells | 4.4 | |
| CD71+_EarlyErythroid | 3.45 | |
| CD8+_Tcells | 3.6 | |
| CardiacMyocytes | 5.15 | |
| Caudatenucleus | 3.3 | |
| Cerebellum | 3 | |
| CerebellumPeduncles | 4.15 | |
| CiliaryGanglion | 2.65 | |
| CingulateCortex | 3.8 | |
| Colorectaladenocarcinoma | 3.7 | |
| DorsalRootGanglion | 2.95 | |
| FetalThyroid | 3.6 | |
| Fetalbrain | 3.65 | |
| Fetalliver | 3.2 | |
| Fetallung | 3.05 | |
| GlobusPallidus | 2.7 | |
| Heart | 4.7 | |
| Hypothalamus | 4 | |
| Kidney | 3.05 | |
| Leukemia_chronicMyelogenousK-562 | 3.35 | |
| Leukemia_promyelocytic-HL-60 | 3.25 | |
| Leukemialymphoblastic(MOLT-4) | 2.9 | |
| Liver | 4.9 | |
| Lung | 4 | |
| Lymphnode | 3.15 | |
| Lymphoma_burkitts(Daudi) | 4.7 | |
| Lymphoma_burkitts(Raji) | 5.15 | |
| MedullaOblongata | 3.35 | |
| OccipitalLobe | 3.3 | |
| OlfactoryBulb | 2.9 | |
| Ovary | 2.45 | |
| Pancreas | 3 | |
| PancreaticIslet | 3.95 | |
| ParietalLobe | 3.9 | |
| Pituitary | 4.3 | |
| Placenta | 3.8 | |
| Pons | 3.5 | |
| PrefrontalCortex | 4.6 | |
| Prostate | 4.3 | |
| Salivarygland | 2.95 | |
| SkeletalMuscle | 4.3 | |
| Skin | 2.9 | |
| SmoothMuscle | 4.2 | |
| Spinalcord | 3.9 | |
| SubthalamicNucleus | 3.4 | |
| SuperiorCervicalGanglion | 4.45 | |
| TemporalLobe | 3.35 | |
| Testis | 3.15 | |
| TestisGermCell | 3.05 | |
| TestisIntersitial | 3.1 | |
| TestisLeydigCell | 4.4 | |
| TestisSeminiferousTubule | 3.15 | |
| Thalamus | 3.75 | |
| Thymus | 2.9 | |
| Thyroid | 4.6 | |
| Tongue | 3.6 | |
| Tonsil | 3.6 | |
| Trachea | 3.1 | |
| TrigeminalGanglion | 3.7 | |
| Uterus | 3 | |
| UterusCorpus | 3.3 | |
| WholeBlood | 4.1 | |
| Wholebrain | 3.1 | |
| colon | 3.7 | |
| pineal_day | 4.62 | |
| pineal_night | 4.54 | |
| retina | 4.475 | |
| small_intestine | 3.55 | |
- Probe name: CUST_16836_PI416261804
- Donor H0351.2001
- Sex: Male Age: 24 years Race/Ethnicity: African American Handedness: Left
- Tissue Receipt Date: 7/29/2009 Serology: Pass Tissue pH :6.72 Additional Medical Information :History of asthma
- Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
- Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
| Tissue | Expression(mean ± stddev) | Expression Bar |
|---|---|---|
| Amygdala | 2.54 ± 0.98 | ![](../"images/bar_3.png"){kind=small}   |
| Basal Forebrain | 1.95 ± 0.26 | |
| Basal Part of Pons | 1.86 ± 0.59 | |
| Cerebellar Cortex | 1.81 ± 0.84 | |
| Cerebellar Nuclei | 2.18 ± 0.77 | |
| Claustrum | 2.89 ± 0.9 | |
| Epithalamus | 1.58 ± 0.76 | |
| Frontal Lobe | 1.84 ± 0.77 | |
| Globus Pallidus | 2.54 ± 0.53 | |
| Hypothalamus | 1.74 ± 0.65 | |
| Insula | 2 ± 0.85 | |
| Limbic Lobe | 2.02 ± 0.7 | |
| Mesencephalon | 2.07 ± 0.79 | |
| Myelencephalon | 2.01 ± 0.78 | |
| Occipital Lobe | 1.96 ± 0.83 | |
| Parietal Lobe | 1.96 ± 0.71 | |
| Pontine Tegmentum | 1.99 ± 0.74 | |
| Striatum | 2.11 ± 0.62 | |
| Subthalamus | 2.02 ± 0.85 | |
| Temporal Lobe | 1.94 ± 0.8 | |
| Thalamus | 1.91 ± 0.73 | |
| White Matter | 2.63 ± 0.51 | |
Mouse Brain ISH 
| Gene Symbol | Brain Structure ID | Brain Structure Name | Express Desity/Level (Meatured by ISH) | Express Bar |
|---|---|---|---|---|
| Esr2 | CB | Cerebellum | 2.35 |  |
| 3.94 | | |||
| Esr2 | CTX | Cerebral cortex | 0.68 | |
| 0.88 | | |||
| Esr2 | HIP | Hippocampal region | 0.8 | |
| 0.88 | | |||
| Esr2 | HPF | Hippocampal formation | 0.98 | |
| 0.99 | | |||
| Esr2 | HY | Hypothalamus | 1.1 | |
| 1 | | |||
| Esr2 | LSX | Lateral septal complex | 0.22 | |
| 0.12 | | |||
| Esr2 | MB | Midbrain | 1.08 | |
| 1.41 | | |||
| Esr2 | MY | Medulla | 1.6 | |
| 1.64 | | |||
| Esr2 | OLF | Olfactory bulb | 1.97 | |
| 2.48 | | |||
| Esr2 | P | Pons | 0.72 | |
| 0.94 | | |||
| Esr2 | PAL | Pallidum | 3.03 | |
| 3.41 | | |||
| Esr2 | RHP | Retrohippocampal region | 1.29 | |
| 1.14 | | |||
| Esr2 | sAMY | Striatum-like amygdalar nuclei | 8.62 | |
| 8.87 | | |||
| Esr2 | STR | Striatum | 1.28 | |
| 1.29 | | |||
| Esr2 | STRd | Striatum dorsal region | 0.42 | |
| 0.42 | | |||
| Esr2 | STRv | Striatum ventral region | 0.55 | |
| 0.5 | | |||
| Esr2 | TH | Thalamus | 2.59 | |
| 3.93 | |
Peptide