AutismKB 2.0

Annotation Detail for ESRRG


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Basic Information Top
Gene Symbol:ESRRG ( DKFZp781L1617,ERR3,ERRgamma,FLJ16023,KIAA0832,NR3B3 )
Gene Full Name: estrogen-related receptor gamma
Band: 1q41
Quick LinksEntrez ID:2104; OMIM: 602969; Uniprot ID:ERR3_HUMAN; ENSEMBL ID: ENSG00000196482; HGNC ID: 3474
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body0 / 707610 
blastocyst0 / 623190 
fetus11 / 56401219
neonate0 / 310970 
infant0 / 236200 
juvenile0 / 555560 
adult50 / 193912125
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor1 / 1279478
bladder carcinoma0 / 174750 
breast (mammary gland) tumor1 / 9417810
cervical tumor0 / 343660 
chondrosarcoma0 / 828230 
colorectal tumor0 / 1142460 
esophageal tumor0 / 172900 
gastrointestinal tumor0 / 1193690 
germ cell tumor16 / 26384560
glioma0 / 1068830 
head and neck tumor1 / 1363027
kidney tumor1 / 6895914
leukemia0 / 958420 
liver tumor0 / 963590 
lung tumor0 / 1031270 
lymphoma0 / 717550 
non-neoplasia0 / 972500 
normal84 / 336030724
ovarian tumor0 / 766820 
pancreatic tumor0 / 1046160 
primitive neuroectodermal tumor of the CNS1 / 1256807
prostate cancer0 / 1026800 
retinoblastoma1 / 4635621
skin tumor0 / 1249490 
soft tissue/muscle tissue tumor0 / 1251910 
uterine tumor1 / 9025711
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland1 / 3319730
ascites0 / 400150 
bladder0 / 297570 
blood0 / 1234780 
bone0 / 716550 
bone marrow0 / 488010 
brain24 / 110098921
cervix0 / 481710 
connective tissue0 / 1492550 
ear0 / 162120 
embryonic tissue2 / 2157229
esophagus0 / 202090 
eye14 / 21105466
heart3 / 8962633
intestine1 / 2344724
kidney7 / 21177733
larynx0 / 241450 
liver0 / 2077430 
lung0 / 3369740 
lymph0 / 442700 
lymph node0 / 916100 
mammary gland1 / 1532716
mouth1 / 6705214
muscle2 / 10771518
nerve0 / 157680 
ovary0 / 1020510 
pancreas0 / 2148120 
parathyroid0 / 205390 
pharynx0 / 413280 
pituitary gland0 / 165850 
placenta24 / 28082585
prostate0 / 1893450 
salivary gland1 / 2015549
skin0 / 2105740 
spleen0 / 539520 
stomach0 / 966190 
testis8 / 33044224
thymus0 / 811310 
thyroid0 / 474730 
tonsil0 / 169990 
trachea2 / 5241338
umbilical cord0 / 136800 
uterus1 / 2328784
vascular0 / 517800 
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 207981_s_at
Cell line Expression level Expression bar
721_B_lymphoblasts11.05
Adipocyte10.8
AdrenalCortex13.35
Adrenalgland10.2
Amygdala14.25
Appendix15.75
AtrioventricularNode12.8
BDCA4+_DentriticCells9.85
Bonemarrow12.5
BronchialEpithelialCells10.95
CD105+_Endothelial11.3
CD14+_Monocytes11.8
CD19+_BCells(neg._sel.)11.2
CD33+_Myeloid13.6
CD34+14.85
CD4+_Tcells11.45
CD56+_NKCells12.6
CD71+_EarlyErythroid10.4
CD8+_Tcells9.05
CardiacMyocytes17.05
Caudatenucleus10.1
Cerebellum11.25
CerebellumPeduncles14.05
CiliaryGanglion10.35
CingulateCortex12.15
Colorectaladenocarcinoma11.1
DorsalRootGanglion10.7
FetalThyroid11.5
Fetalbrain11.15
Fetalliver10.15
Fetallung8.5
GlobusPallidus9.2
Heart18.85
Hypothalamus13.2
Kidney11.2
Leukemia_chronicMyelogenousK-5629.55
Leukemia_promyelocytic-HL-6010.15
Leukemialymphoblastic(MOLT-4)8.65
Liver17.35
Lung12.1
Lymphnode9
Lymphoma_burkitts(Daudi)14.65
Lymphoma_burkitts(Raji)18.5
MedullaOblongata12.7
OccipitalLobe11.05
OlfactoryBulb8.95
Ovary8.6
Pancreas9.6
PancreaticIslet12.75
ParietalLobe12.95
Pituitary13.35
Placenta71.4
Pons11.1
PrefrontalCortex24.15
Prostate14.35
Salivarygland10.65
SkeletalMuscle16.7
Skin10.1
SmoothMuscle12.15
Spinalcord12.2
SubthalamicNucleus11.05
SuperiorCervicalGanglion15.35
TemporalLobe11.65
Testis8.95
TestisGermCell8.85
TestisIntersitial9.9
TestisLeydigCell11.75
TestisSeminiferousTubule9.25
Thalamus12
Thymus8.05
Thyroid20.7
Tongue13.8
Tonsil11.15
Trachea9.3
TrigeminalGanglion14.8
Uterus9
UterusCorpus11
WholeBlood12.4
Wholebrain11.05
colon10.95
pineal_day861.22
pineal_night563.18
retina16.9
small_intestine11.95
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: A_24_P7965
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala5.01 ± 0.42
Basal Forebrain5.5 ± 0.38
Basal Part of Pons6.37 ± 0.2
Cerebellar Cortex5.48 ± 0.61
Cerebellar Nuclei6.56 ± 0.56
Claustrum5.28 ± 0.5
Epithalamus4.72 ± 0.5
Frontal Lobe5.23 ± 0.58
Globus Pallidus5.73 ± 0.49
Hypothalamus4.72 ± 0.77
Insula4.94 ± 0.78
Limbic Lobe5.18 ± 0.65
Mesencephalon5.28 ± 0.65
Myelencephalon5.35 ± 0.71
Occipital Lobe6.22 ± 0.77
Parietal Lobe5.64 ± 0.57
Pontine Tegmentum5.21 ± 0.57
Striatum5.29 ± 0.57
Subthalamus5.75 ± 0.46
Temporal Lobe5.1 ± 0.6
Thalamus5.42 ± 0.54
White Matter3.57 ± 0.53
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
EsrrgCBCerebellum11.69
14.92
EsrrgCTXCerebral cortex3.83
3.5
EsrrgHIPHippocampal region1.65
1.99
EsrrgHPFHippocampal formation1.53
1.69
EsrrgHYHypothalamus1.66
1.82
EsrrgLSXLateral septal complex0.24
0.34
EsrrgMBMidbrain5.3
7.97
EsrrgMYMedulla11.15
17.61
EsrrgOLFOlfactory bulb2.58
3.02
EsrrgPPons13.83
19.46
EsrrgPALPallidum7.34
9.54
EsrrgRHPRetrohippocampal region1.43
1.37
EsrrgsAMYStriatum-like amygdalar nuclei4.08
4.41
EsrrgSTRStriatum0.76
0.85
EsrrgSTRdStriatum dorsal region0.35
0.45
EsrrgSTRvStriatum ventral region1.07
0.98
EsrrgTHThalamus6.54
8.49
Peptide Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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