AutismKB 2.0

Annotation Detail for ETS2


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Basic Information Top
Gene Symbol:ETS2 ( ETS2IT1 )
Gene Full Name: v-ets erythroblastosis virus E26 oncogene homolog 2 (avian)
Band: 21q22.2
Quick LinksEntrez ID:2114; OMIM: 164740; Uniprot ID:ETS2_HUMAN; ENSEMBL ID: ENSG00000157557; HGNC ID: 3489
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body1 / 7076114
blastocyst2 / 6231932
fetus56 / 56401299
neonate4 / 31097128
infant0 / 236200 
juvenile2 / 5555635
adult242 / 1939121124
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma4 / 17475228
breast (mammary gland) tumor3 / 9417831
cervical tumor4 / 34366116
chondrosarcoma14 / 82823169
colorectal tumor21 / 114246183
esophageal tumor4 / 17290231
gastrointestinal tumor20 / 119369167
germ cell tumor20 / 26384575
glioma11 / 106883102
head and neck tumor27 / 136302198
kidney tumor2 / 6895929
leukemia12 / 95842125
liver tumor7 / 9635972
lung tumor5 / 10312748
lymphoma1 / 7175513
non-neoplasia7 / 9725071
normal345 / 3360307102
ovarian tumor6 / 7668278
pancreatic tumor30 / 104616286
primitive neuroectodermal tumor of the CNS2 / 12568015
prostate cancer2 / 10268019
retinoblastoma0 / 463560 
skin tumor0 / 1249490 
soft tissue/muscle tissue tumor4 / 12519131
uterine tumor14 / 90257155
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue7 / 13106534
adrenal gland1 / 3319730
ascites2 / 4001549
bladder8 / 29757268
blood19 / 123478153
bone4 / 7165555
bone marrow6 / 48801122
brain101 / 110098991
cervix8 / 48171166
connective tissue18 / 149255120
ear1 / 1621261
embryonic tissue6 / 21572227
esophagus4 / 20209197
eye12 / 21105456
heart11 / 89626122
intestine49 / 234472208
kidney10 / 21177747
larynx8 / 24145331
liver35 / 207743168
lung59 / 336974175
lymph0 / 442700 
lymph node10 / 91610109
mammary gland6 / 15327139
mouth17 / 67052253
muscle1 / 1077159
nerve2 / 15768126
ovary9 / 10205188
pancreas51 / 214812237
parathyroid2 / 2053997
pharynx3 / 4132872
pituitary gland1 / 1658560
placenta34 / 280825121
prostate11 / 18934558
salivary gland3 / 20155148
skin10 / 21057447
spleen3 / 5395255
stomach24 / 96619248
testis8 / 33044224
thymus11 / 81131135
thyroid1 / 4747321
tonsil0 / 169990 
trachea27 / 52413515
umbilical cord0 / 136800 
uterus38 / 232878163
vascular8 / 51780154
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 201328_at
Cell line Expression level Expression bar
721_B_lymphoblasts38
Adipocyte25.75
AdrenalCortex36.6
Adrenalgland33.6
Amygdala65.1
Appendix39.95
AtrioventricularNode25.5
BDCA4+_DentriticCells55.25
Bonemarrow31.4
BronchialEpithelialCells72.25
CD105+_Endothelial47.25
CD14+_Monocytes180.1
CD19+_BCells(neg._sel.)25.55
CD33+_Myeloid276.05
CD34+344.2
CD4+_Tcells27.65
CD56+_NKCells31.9
CD71+_EarlyErythroid25.95
CD8+_Tcells21.75
CardiacMyocytes47.1
Caudatenucleus27.25
Cerebellum30.05
CerebellumPeduncles40.8
CiliaryGanglion54.05
CingulateCortex62.25
Colorectaladenocarcinoma51.05
DorsalRootGanglion23.45
FetalThyroid42.4
Fetalbrain32.1
Fetalliver24.15
Fetallung319.75
GlobusPallidus61.25
Heart44.95
Hypothalamus37.95
Kidney32.15
Leukemia_chronicMyelogenousK-56225.35
Leukemia_promyelocytic-HL-6024.15
Leukemialymphoblastic(MOLT-4)25.3
Liver44.85
Lung534.6
Lymphnode47.6
Lymphoma_burkitts(Daudi)43.6
Lymphoma_burkitts(Raji)36.35
MedullaOblongata61.8
OccipitalLobe54.95
OlfactoryBulb33.5
Ovary26
Pancreas101.65
PancreaticIslet40.4
ParietalLobe57.15
Pituitary46.85
Placenta56.9
Pons37.5
PrefrontalCortex75.7
Prostate84.55
Salivarygland31.85
SkeletalMuscle94.7
Skin58.85
SmoothMuscle31.35
Spinalcord41.4
SubthalamicNucleus66.9
SuperiorCervicalGanglion41.9
TemporalLobe51.05
Testis25.25
TestisGermCell22
TestisIntersitial23.2
TestisLeydigCell25.75
TestisSeminiferousTubule30.4
Thalamus46.2
Thymus31.1
Thyroid48.95
Tongue53.55
Tonsil31.15
Trachea47.25
TrigeminalGanglion45.25
Uterus66.75
UterusCorpus50.9
WholeBlood67.25
Wholebrain217.2
colon120.8
pineal_day55.88
pineal_night64.1
retina80.7
small_intestine139.95
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: A_24_P382661
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala8.89 ± 0.48
Basal Forebrain7.89 ± 0.19
Basal Part of Pons7.81 ± 0.31
Cerebellar Cortex7.74 ± 0.28
Cerebellar Nuclei8.16 ± 0.32
Claustrum8.85 ± 0.41
Epithalamus7.26 ± 0.61
Frontal Lobe8.26 ± 0.49
Globus Pallidus8.01 ± 0.66
Hypothalamus7.84 ± 0.35
Insula8.23 ± 0.36
Limbic Lobe8.41 ± 0.49
Mesencephalon8.3 ± 0.46
Myelencephalon8.31 ± 0.59
Occipital Lobe8.78 ± 0.48
Parietal Lobe8.6 ± 0.44
Pontine Tegmentum8.28 ± 0.45
Striatum7.56 ± 0.87
Subthalamus7.82 ± 0.48
Temporal Lobe8.44 ± 0.34
Thalamus8.37 ± 0.35
White Matter7.34 ± 0.68
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Ets2CBCerebellum75.89
45.83
Ets2CTXCerebral cortex36.19
31.39
Ets2HIPHippocampal region40.4
31.86
Ets2HPFHippocampal formation48.14
37.93
Ets2HYHypothalamus24.94
22.29
Ets2LSXLateral septal complex39
30.29
Ets2MBMidbrain8.41
6.16
Ets2MYMedulla7.01
4.87
Ets2OLFOlfactory bulb37.28
32.04
Ets2PPons6
4.8
Ets2PALPallidum13.42
11.13
Ets2RHPRetrohippocampal region62.66
47.7
Ets2sAMYStriatum-like amygdalar nuclei52.71
43.84
Ets2STRStriatum22.9
18.04
Ets2STRdStriatum dorsal region5.58
4.26
Ets2STRvStriatum ventral region57.11
40.49
Ets2THThalamus4.92
3.68
Peptide Top
Peptide Name Peptide Lengh Peptide Start Peptide End Peptide Sequence Source
PAp00011394 16 377 392 SCQSFISWTGDGWEFK Peptide Atlas

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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