AutismKB 2.0

Annotation Detail for ETV4


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Basic Information Top
Gene Symbol:ETV4 ( E1A-F,E1AF,PEA3,PEAS3 )
Gene Full Name: ets variant 4
Band: 17q21.31
Quick LinksEntrez ID:2118; OMIM: 600711; Uniprot ID:ETV4_HUMAN; ENSEMBL ID: ENSG00000175832; HGNC ID: 3493
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body6 / 7076184
blastocyst5 / 6231980
fetus11 / 56401219
neonate1 / 3109732
infant0 / 236200 
juvenile7 / 55556125
adult60 / 193912130
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma0 / 174750 
breast (mammary gland) tumor9 / 9417895
cervical tumor0 / 343660 
chondrosarcoma2 / 8282324
colorectal tumor18 / 114246157
esophageal tumor0 / 172900 
gastrointestinal tumor15 / 119369125
germ cell tumor20 / 26384575
glioma3 / 10688328
head and neck tumor5 / 13630236
kidney tumor1 / 6895914
leukemia1 / 9584210
liver tumor14 / 96359145
lung tumor7 / 10312767
lymphoma0 / 717550 
non-neoplasia0 / 972500 
normal39 / 336030711
ovarian tumor11 / 76682143
pancreatic tumor2 / 10461619
primitive neuroectodermal tumor of the CNS12 / 12568095
prostate cancer1 / 1026809
retinoblastoma0 / 463560 
skin tumor19 / 124949152
soft tissue/muscle tissue tumor9 / 12519171
uterine tumor4 / 9025744
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland0 / 331970 
ascites1 / 4001524
bladder0 / 297570 
blood1 / 1234788
bone1 / 7165513
bone marrow0 / 488010 
brain15 / 110098913
cervix0 / 481710 
connective tissue1 / 1492556
ear0 / 162120 
embryonic tissue15 / 21572269
esophagus0 / 202090 
eye1 / 2110544
heart0 / 896260 
intestine25 / 234472106
kidney1 / 2117774
larynx0 / 241450 
liver14 / 20774367
lung9 / 33697426
lymph0 / 442700 
lymph node0 / 916100 
mammary gland11 / 15327171
mouth1 / 6705214
muscle5 / 10771546
nerve0 / 157680 
ovary13 / 102051127
pancreas2 / 2148129
parathyroid0 / 205390 
pharynx0 / 413280 
pituitary gland0 / 165850 
placenta0 / 2808250 
prostate2 / 18934510
salivary gland0 / 201550 
skin20 / 21057494
spleen0 / 539520 
stomach13 / 96619134
testis10 / 33044230
thymus0 / 811310 
thyroid4 / 4747384
tonsil0 / 169990 
trachea0 / 524130 
umbilical cord0 / 136800 
uterus9 / 23287838
vascular0 / 517800 
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 211603_s_at
Cell line Expression level Expression bar
721_B_lymphoblasts13.9
Adipocyte12.2
AdrenalCortex15.1
Adrenalgland13
Amygdala9.9
Appendix13.7
AtrioventricularNode11.5
BDCA4+_DentriticCells8.75
Bonemarrow11.85
BronchialEpithelialCells11.1
CD105+_Endothelial6.9
CD14+_Monocytes7.55
CD19+_BCells(neg._sel.)9
CD33+_Myeloid11.15
CD34+10.5
CD4+_Tcells7.75
CD56+_NKCells8.5
CD71+_EarlyErythroid10.9
CD8+_Tcells6.9
CardiacMyocytes15.6
Caudatenucleus14.25
Cerebellum11.45
CerebellumPeduncles15.1
CiliaryGanglion11.15
CingulateCortex14.6
Colorectaladenocarcinoma65.8
DorsalRootGanglion9.4
FetalThyroid10.85
Fetalbrain11.8
Fetalliver10.3
Fetallung9.35
GlobusPallidus14.25
Heart15.4
Hypothalamus12.4
Kidney11.75
Leukemia_chronicMyelogenousK-56214.65
Leukemia_promyelocytic-HL-6010.6
Leukemialymphoblastic(MOLT-4)11.45
Liver15.7
Lung9.7
Lymphnode10.95
Lymphoma_burkitts(Daudi)15.2
Lymphoma_burkitts(Raji)14.75
MedullaOblongata10.55
OccipitalLobe10.75
OlfactoryBulb10.15
Ovary10.55
Pancreas12.1
PancreaticIslet11.1
ParietalLobe12.5
Pituitary19.85
Placenta12.1
Pons15.15
PrefrontalCortex14.65
Prostate13.65
Salivarygland9.4
SkeletalMuscle16.35
Skin9.9
SmoothMuscle12.95
Spinalcord13.6
SubthalamicNucleus10.75
SuperiorCervicalGanglion13.5
TemporalLobe16.55
Testis10.05
TestisGermCell10.7
TestisIntersitial9.7
TestisLeydigCell12.3
TestisSeminiferousTubule12.15
Thalamus13.45
Thymus7.95
Thyroid14.3
Tongue12.2
Tonsil11.85
Trachea15.85
TrigeminalGanglion10.3
Uterus8.55
UterusCorpus11.65
WholeBlood12.25
Wholebrain9.65
colon8.3
pineal_day12.08
pineal_night11.2
retina13.225
small_intestine8.5
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: A_23_P431776
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala3.18 ± 1.01
Basal Forebrain2.49 ± 0.36
Basal Part of Pons2.34 ± 0.54
Cerebellar Cortex2.32 ± 0.65
Cerebellar Nuclei2.75 ± 0.68
Claustrum3.16 ± 0.66
Epithalamus2.35 ± 0.93
Frontal Lobe2.77 ± 0.78
Globus Pallidus2.55 ± 0.54
Hypothalamus2.79 ± 1.05
Insula2.23 ± 0.83
Limbic Lobe2.43 ± 0.86
Mesencephalon2.78 ± 0.7
Myelencephalon2.68 ± 0.73
Occipital Lobe3.44 ± 0.62
Parietal Lobe2.92 ± 0.77
Pontine Tegmentum2.86 ± 0.94
Striatum2.56 ± 0.82
Subthalamus2.69 ± 0.76
Temporal Lobe2.59 ± 0.75
Thalamus2.57 ± 0.72
White Matter2.07 ± 0.36
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Etv4CBCerebellum23.78
31.87
Etv4CTXCerebral cortex4.18
3.65
Etv4HIPHippocampal region5.18
5.9
Etv4HPFHippocampal formation6.63
6.29
Etv4HYHypothalamus2.63
2.19
Etv4LSXLateral septal complex2.7
3.62
Etv4MBMidbrain2.31
2.5
Etv4MYMedulla4.11
3.77
Etv4OLFOlfactory bulb8.81
6.86
Etv4PPons1.98
2.24
Etv4PALPallidum0.64
0.72
Etv4RHPRetrohippocampal region9.39
7
Etv4sAMYStriatum-like amygdalar nuclei2.55
2.67
Etv4STRStriatum1.95
1.8
Etv4STRdStriatum dorsal region1.71
1.57
Etv4STRvStriatum ventral region1.81
1.27
Etv4THThalamus2.7
2.9
Peptide Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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