AutismKB 2.0

Annotation Detail for EVI2B


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Basic Information Top
Gene Symbol:EVI2B ( D17S376,EVDB )
Gene Full Name: ecotropic viral integration site 2B
Band: 17q11.2
Quick LinksEntrez ID:2124; OMIM: 158381; Uniprot ID:EVI2B_HUMAN; ENSEMBL ID: ENSG00000185862; HGNC ID: 3500
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body0 / 707610 
blastocyst0 / 623190 
fetus4 / 5640127
neonate12 / 31097385
infant0 / 236200 
juvenile2 / 5555635
adult38 / 193912119
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor1 / 1279478
bladder carcinoma1 / 1747557
breast (mammary gland) tumor1 / 9417810
cervical tumor0 / 343660 
chondrosarcoma4 / 8282348
colorectal tumor0 / 1142460 
esophageal tumor0 / 172900 
gastrointestinal tumor1 / 1193698
germ cell tumor4 / 26384515
glioma0 / 1068830 
head and neck tumor0 / 1363020 
kidney tumor0 / 689590 
leukemia16 / 95842166
liver tumor1 / 9635910
lung tumor0 / 1031270 
lymphoma5 / 7175569
non-neoplasia2 / 9725020
normal110 / 336030732
ovarian tumor2 / 7668226
pancreatic tumor0 / 1046160 
primitive neuroectodermal tumor of the CNS0 / 1256800 
prostate cancer0 / 1026800 
retinoblastoma0 / 463560 
skin tumor0 / 1249490 
soft tissue/muscle tissue tumor0 / 1251910 
uterine tumor5 / 9025755
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland1 / 3319730
ascites0 / 400150 
bladder0 / 297570 
blood73 / 123478591
bone0 / 716550 
bone marrow6 / 48801122
brain7 / 11009896
cervix0 / 481710 
connective tissue8 / 14925553
ear0 / 162120 
embryonic tissue0 / 2157220 
esophagus0 / 202090 
eye0 / 2110540 
heart0 / 896260 
intestine2 / 2344728
kidney3 / 21177714
larynx0 / 241450 
liver2 / 2077439
lung3 / 3369748
lymph2 / 4427045
lymph node9 / 9161098
mammary gland2 / 15327113
mouth0 / 670520 
muscle2 / 10771518
nerve0 / 157680 
ovary2 / 10205119
pancreas0 / 2148120 
parathyroid0 / 205390 
pharynx3 / 4132872
pituitary gland0 / 165850 
placenta5 / 28082517
prostate0 / 1893450 
salivary gland0 / 201550 
skin0 / 2105740 
spleen7 / 53952129
stomach3 / 9661931
testis2 / 3304426
thymus9 / 81131110
thyroid0 / 474730 
tonsil0 / 169990 
trachea2 / 5241338
umbilical cord0 / 136800 
uterus6 / 23287825
vascular1 / 5178019
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 211742_s_at
Cell line Expression level Expression bar
721_B_lymphoblasts184.4
Adipocyte10.3
AdrenalCortex14.4
Adrenalgland9.9
Amygdala10.2
Appendix18.6
AtrioventricularNode20.6
BDCA4+_DentriticCells929.75
Bonemarrow139.5
BronchialEpithelialCells9.2
CD105+_Endothelial17.75
CD14+_Monocytes1675.95
CD19+_BCells(neg._sel.)1412.45
CD33+_Myeloid2020.55
CD34+220.05
CD4+_Tcells431.05
CD56+_NKCells908.9
CD71+_EarlyErythroid10.55
CD8+_Tcells405.45
CardiacMyocytes18
Caudatenucleus10.3
Cerebellum8.65
CerebellumPeduncles14.15
CiliaryGanglion15.5
CingulateCortex12.65
Colorectaladenocarcinoma9.5
DorsalRootGanglion14.7
FetalThyroid11.4
Fetalbrain10
Fetalliver9.9
Fetallung8.9
GlobusPallidus10.85
Heart20.6
Hypothalamus11.45
Kidney10.95
Leukemia_chronicMyelogenousK-5629.45
Leukemia_promyelocytic-HL-60123.1
Leukemialymphoblastic(MOLT-4)8.6
Liver19.85
Lung13.15
Lymphnode437
Lymphoma_burkitts(Daudi)66.25
Lymphoma_burkitts(Raji)75.25
MedullaOblongata9.5
OccipitalLobe9.5
OlfactoryBulb9.5
Ovary9.7
Pancreas9.5
PancreaticIslet12.1
ParietalLobe13.65
Pituitary13.15
Placenta8.6
Pons10.8
PrefrontalCortex12.1
Prostate12
Salivarygland30.85
SkeletalMuscle25.9
Skin19.05
SmoothMuscle11.25
Spinalcord16.2
SubthalamicNucleus10.9
SuperiorCervicalGanglion29.25
TemporalLobe13.8
Testis9.1
TestisGermCell8.35
TestisIntersitial9.2
TestisLeydigCell12.65
TestisSeminiferousTubule9.4
Thalamus11.45
Thymus18.45
Thyroid12.45
Tongue15.45
Tonsil82.8
Trachea14.3
TrigeminalGanglion22.95
Uterus8.3
UterusCorpus11.75
WholeBlood2639.85
Wholebrain8.1
colon10.55
pineal_day11.36
pineal_night11.42
retina11.7
small_intestine16.05
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: CUST_10246_PI416261804
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala2.03 ± 1
Basal Forebrain1.7 ± 0.27
Basal Part of Pons1.55 ± 0.69
Cerebellar Cortex1.37 ± 0.48
Cerebellar Nuclei2.08 ± 0.75
Claustrum2.45 ± 0.8
Epithalamus1.61 ± 0.66
Frontal Lobe1.54 ± 0.71
Globus Pallidus2.66 ± 0.57
Hypothalamus1.75 ± 0.75
Insula1.45 ± 0.42
Limbic Lobe1.64 ± 0.67
Mesencephalon1.75 ± 0.71
Myelencephalon1.72 ± 0.72
Occipital Lobe1.78 ± 0.74
Parietal Lobe1.61 ± 0.74
Pontine Tegmentum1.66 ± 0.69
Striatum1.9 ± 0.67
Subthalamus1.73 ± 0.61
Temporal Lobe1.55 ± 0.61
Thalamus1.69 ± 0.69
White Matter4.27 ± 0.37
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Evi2bCBCerebellum18.67
18.24
Evi2bCTXCerebral cortex52.99
34.44
Evi2bHIPHippocampal region33.01
31.39
Evi2bHPFHippocampal formation36.13
30.67
Evi2bHYHypothalamus29.92
21.81
Evi2bLSXLateral septal complex22.41
14.14
Evi2bMBMidbrain20.72
16.3
Evi2bMYMedulla36.36
33.75
Evi2bOLFOlfactory bulb84.72
66.4
Evi2bPPons28.19
25.29
Evi2bPALPallidum30.59
22.7
Evi2bRHPRetrohippocampal region44.06
31.22
Evi2bsAMYStriatum-like amygdalar nuclei48.8
32.69
Evi2bSTRStriatum37.1
23.97
Evi2bSTRdStriatum dorsal region33.18
21.12
Evi2bSTRvStriatum ventral region50.73
31.9
Evi2bTHThalamus40.74
28.7
Peptide Top
Peptide Name Peptide Lengh Peptide Start Peptide End Peptide Sequence Source
EVI2B_HUMAN_279 11 279 289 STLLADDLEIK PRIDE
PAp00037788 24 242 265 SPFADGETPDICMDNIRENEISTK Peptide Atlas

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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