Annotation Detail for EVPL
Basic Information Top
| Gene Symbol: | EVPL ( EVPK ) |
|---|---|
| Gene Full Name: | envoplakin |
| Band: | 17q25.1 |
| Quick Links | Entrez ID:2125; OMIM: 601590; Uniprot ID:EVPL_HUMAN; ENSEMBL ID: ENSG00000167880; HGNC ID: 3503 |
| Relate to Another Database: | SFARIGene; denovo-db |
- Unigene ID: Hs.500635
| Pool Name | Gene EST/Total EST in pool | Transcripts per million(TPM) | Bar based on TPM |
|---|---|---|---|
 | |||
| embryoid body | 0 / 70761 | 0 | |
| blastocyst | 0 / 62319 | 0 | |
| fetus | 7 / 564012 | 12 |  |
| neonate | 0 / 31097 | 0 | |
| infant | 0 / 23620 | 0 | |
| juvenile | 0 / 55556 | 0 | |
| adult | 63 / 1939121 | 32 | |
| Pool Name | Gene EST/Total EST in pool | Transcripts per million(TPM) | Bar based on TPM |
|---|---|---|---|
| |||
| adrenal tumor | 0 / 12794 | 0 | |
| bladder carcinoma | 0 / 17475 | 0 | |
| breast (mammary gland) tumor | 3 / 94178 | 31 | |
| cervical tumor | 1 / 34366 | 29 | |
| chondrosarcoma | 0 / 82823 | 0 | |
| colorectal tumor | 11 / 114246 | 96 |  |
| esophageal tumor | 1 / 17290 | 57 | |
| gastrointestinal tumor | 0 / 119369 | 0 | |
| germ cell tumor | 0 / 263845 | 0 | |
| glioma | 0 / 106883 | 0 | |
| head and neck tumor | 15 / 136302 | 110 | |
| kidney tumor | 0 / 68959 | 0 | |
| leukemia | 2 / 95842 | 20 | |
| liver tumor | 1 / 96359 | 10 |  |
| lung tumor | 6 / 103127 | 58 | |
| lymphoma | 0 / 71755 | 0 | |
| non-neoplasia | 2 / 97250 | 20 | |
| normal | 30 / 3360307 | 8 | |
| ovarian tumor | 3 / 76682 | 39 | |
| pancreatic tumor | 3 / 104616 | 28 | |
| primitive neuroectodermal tumor of the CNS | 0 / 125680 | 0 | |
| prostate cancer | 4 / 102680 | 38 | |
| retinoblastoma | 2 / 46356 | 43 | |
| skin tumor | 0 / 124949 | 0 | |
| soft tissue/muscle tissue tumor | 0 / 125191 | 0 | |
| uterine tumor | 5 / 90257 | 55 | |
| Pool Name | Gene EST/Total EST in pool | Transcripts per million(TPM) | Bar based on TPM |
|---|---|---|---|
| |||
| adipose tissue | 0 / 13106 | 0 | |
| adrenal gland | 0 / 33197 | 0 | |
| ascites | 0 / 40015 | 0 | |
| bladder | 3 / 29757 | 100 | |
| blood | 2 / 123478 | 16 | |
| bone | 0 / 71655 | 0 | |
| bone marrow | 0 / 48801 | 0 | |
| brain | 0 / 1100989 | 0 | |
| cervix | 1 / 48171 | 20 | |
| connective tissue | 0 / 149255 | 0 | |
| ear | 0 / 16212 | 0 | |
| embryonic tissue | 0 / 215722 | 0 | |
| esophagus | 1 / 20209 | 49 | |
| eye | 6 / 211054 | 28 | |
| heart | 4 / 89626 | 44 | |
| intestine | 11 / 234472 | 46 | |
| kidney | 2 / 211777 | 9 | |
| larynx | 1 / 24145 | 41 | |
| liver | 1 / 207743 | 4 | |
| lung | 7 / 336974 | 20 | |
| lymph | 0 / 44270 | 0 | |
| lymph node | 0 / 91610 | 0 | |
| mammary gland | 5 / 153271 | 32 | |
| mouth | 5 / 67052 | 74 | |
| muscle | 0 / 107715 | 0 | |
| nerve | 0 / 15768 | 0 | |
| ovary | 3 / 102051 | 29 | |
| pancreas | 3 / 214812 | 13 | |
| parathyroid | 0 / 20539 | 0 | |
| pharynx | 4 / 41328 | 96 | |
| pituitary gland | 0 / 16585 | 0 | |
| placenta | 0 / 280825 | 0 | |
| prostate | 5 / 189345 | 26 | |
| salivary gland | 0 / 20155 | 0 | |
| skin | 7 / 210574 | 33 | |
| spleen | 0 / 53952 | 0 | |
| stomach | 0 / 96619 | 0 | |
| testis | 1 / 330442 | 3 | |
| thymus | 0 / 81131 | 0 | |
| thyroid | 14 / 47473 | 294 |  |
| tonsil | 0 / 16999 | 0 | |
| trachea | 0 / 52413 | 0 | |
| umbilical cord | 0 / 13680 | 0 | |
| uterus | 5 / 232878 | 21 | |
| vascular | 0 / 51780 | 0 |
- Microarray Platform: GeneAtlas U133A, gcrma
- Affymatrix Probe ID: 204503_at
| Cell line | Expression level | Expression bar |
|---|---|---|
| ||
| 721_B_lymphoblasts | 39.9 | |
| Adipocyte | 38.2 | |
| AdrenalCortex | 43.75 | |
| Adrenalgland | 35.9 | |
| Amygdala | 38.55 | |
| Appendix | 37.55 | |
| AtrioventricularNode | 27.95 | |
| BDCA4+_DentriticCells | 37.7 | |
| Bonemarrow | 42.9 | |
| BronchialEpithelialCells | 38.4 | |
| CD105+_Endothelial | 37.65 | |
| CD14+_Monocytes | 37.7 | |
| CD19+_BCells(neg._sel.) | 38.55 | |
| CD33+_Myeloid | 44.95 | |
| CD34+ | 44.95 | |
| CD4+_Tcells | 38.55 | |
| CD56+_NKCells | 40.45 | |
| CD71+_EarlyErythroid | 36.75 | |
| CD8+_Tcells | 35.05 | |
| CardiacMyocytes | 46.9 | |
| Caudatenucleus | 36.85 | |
| Cerebellum | 50.7 | |
| CerebellumPeduncles | 43.25 | |
| CiliaryGanglion | 25.7 | |
| CingulateCortex | 37.8 | |
| Colorectaladenocarcinoma | 42.95 | |
| DorsalRootGanglion | 28.45 | |
| FetalThyroid | 38.8 | |
| Fetalbrain | 36.05 | |
| Fetalliver | 32.5 | |
| Fetallung | 35.3 | |
| GlobusPallidus | 27.3 | |
| Heart | 47.9 | |
| Hypothalamus | 38.4 | |
| Kidney | 66 | |
| Leukemia_chronicMyelogenousK-562 | 43.9 | |
| Leukemia_promyelocytic-HL-60 | 32.8 | |
| Leukemialymphoblastic(MOLT-4) | 76.1 | |
| Liver | 52.8 | |
| Lung | 81.85 | |
| Lymphnode | 32.75 | |
| Lymphoma_burkitts(Daudi) | 49.4 | |
| Lymphoma_burkitts(Raji) | 53.1 | |
| MedullaOblongata | 33.95 | |
| OccipitalLobe | 33.4 | |
| OlfactoryBulb | 29.8 | |
| Ovary | 25.65 | |
| Pancreas | 64.85 | |
| PancreaticIslet | 56.5 | |
| ParietalLobe | 43.75 | |
| Pituitary | 61.05 | |
| Placenta | 40.35 | |
| Pons | 36.2 | |
| PrefrontalCortex | 40.25 | |
| Prostate | 43.65 | |
| Salivarygland | 32.5 | |
| SkeletalMuscle | 45.95 | |
| Skin | 53.8 | |
| SmoothMuscle | 42.05 | |
| Spinalcord | 39.6 | |
| SubthalamicNucleus | 43.45 | |
| SuperiorCervicalGanglion | 43.2 | |
| TemporalLobe | 34.1 | |
| Testis | 50.9 | |
| TestisGermCell | 30.1 | |
| TestisIntersitial | 34.75 | |
| TestisLeydigCell | 37.55 | |
| TestisSeminiferousTubule | 32.75 | |
| Thalamus | 39.25 | |
| Thymus | 28.9 | |
| Thyroid | 48.55 | |
| Tongue | 328.1 | |
| Tonsil | 54.9 | |
| Trachea | 43.3 | |
| TrigeminalGanglion | 39.1 | |
| Uterus | 29.2 | |
| UterusCorpus | 54.4 | |
| WholeBlood | 40.3 | |
| Wholebrain | 30.5 | |
| colon | 37.45 | |
| pineal_day | 38.76 | |
| pineal_night | 33.84 | |
| retina | 43.65 | |
| small_intestine | 36.4 | |
- Probe name: CUST_12772_PI416261804
- Donor H0351.2001
- Sex: Male Age: 24 years Race/Ethnicity: African American Handedness: Left
- Tissue Receipt Date: 7/29/2009 Serology: Pass Tissue pH :6.72 Additional Medical Information :History of asthma
- Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
- Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
| Tissue | Expression(mean ± stddev) | Expression Bar |
|---|---|---|
| Amygdala | 7.29 ± 0.71 | ![](../"images/bar_3.png"){kind=small}   |
| Basal Forebrain | 5.99 ± 0.65 | |
| Basal Part of Pons | 6.73 ± 0.52 | |
| Cerebellar Cortex | 6.52 ± 0.41 | |
| Cerebellar Nuclei | 6.39 ± 0.64 | |
| Claustrum | 7.27 ± 0.88 | |
| Epithalamus | 4.2 ± 0.89 | |
| Frontal Lobe | 6.27 ± 0.8 | |
| Globus Pallidus | 4.21 ± 0.97 | |
| Hypothalamus | 5.99 ± 0.7 | |
| Insula | 6.37 ± 0.63 | |
| Limbic Lobe | 6.77 ± 0.79 | |
| Mesencephalon | 6.25 ± 0.82 | |
| Myelencephalon | 6.11 ± 0.78 | |
| Occipital Lobe | 7 ± 0.68 | |
| Parietal Lobe | 6.63 ± 0.69 | |
| Pontine Tegmentum | 6.59 ± 0.77 | |
| Striatum | 6.74 ± 1.01 | |
| Subthalamus | 6.86 ± 0.27 | |
| Temporal Lobe | 6.42 ± 0.71 | |
| Thalamus | 6.22 ± 0.62 | |
| White Matter | 5.46 ± 0.37 | |
Mouse Brain ISH 
| Gene Symbol | Brain Structure ID | Brain Structure Name | Express Desity/Level (Meatured by ISH) | Express Bar |
|---|---|---|---|---|
| Evpl | CB | Cerebellum | 0.43 | |
| 0.63 | | |||
| Evpl | CTX | Cerebral cortex | 1 | |
| 1.4 | | |||
| Evpl | HIP | Hippocampal region | 0.35 | |
| 0.68 | | |||
| Evpl | HPF | Hippocampal formation | 0.46 | |
| 0.69 | | |||
| Evpl | HY | Hypothalamus | 0.08 | |
| 0.09 | | |||
| Evpl | LSX | Lateral septal complex | 0.12 | |
| 0.14 | | |||
| Evpl | MB | Midbrain | 0.32 | |
| 0.56 | | |||
| Evpl | MY | Medulla | 1.26 | |
| 2.1 | | |||
| Evpl | OLF | Olfactory bulb | 0.18 | |
| 0.21 | | |||
| Evpl | P | Pons | 0.32 | |
| 0.86 | | |||
| Evpl | PAL | Pallidum | 0.16 | |
| 0.17 | | |||
| Evpl | RHP | Retrohippocampal region | 0.66 | |
| 0.75 | | |||
| Evpl | sAMY | Striatum-like amygdalar nuclei | 0.13 | |
| 0.11 | | |||
| Evpl | STR | Striatum | 0.21 | |
| 0.31 | | |||
| Evpl | STRd | Striatum dorsal region | 0.21 | |
| 0.19 | | |||
| Evpl | STRv | Striatum ventral region | 0.29 | |
| 0.93 | | |||
| Evpl | TH | Thalamus | 0.23 | |
| 0.21 | |
| Peptide Name | Peptide Lengh | Peptide Start | Peptide End | Peptide Sequence | Source |
|---|---|---|---|---|---|
| EVPL_HUMAN_1037 | 7 | 1037 | 1043 | IQIQQLR | PRIDE |
| PAp00618998 | 11 | 198 | 208 | SLVGPDAATIR | Peptide Atlas |