Annotation Detail for EXTL3
Basic Information Top
| Gene Symbol: | EXTL3 ( BOTV,DKFZp686C2342,EXTR1,KIAA0519,REG,REGR,RPR ) |
|---|---|
| Gene Full Name: | exostoses (multiple)-like 3 |
| Band: | 8p21.1 |
| Quick Links | Entrez ID:2137; OMIM: 605744; Uniprot ID:EXTL3_HUMAN; ENSEMBL ID: ENSG00000012232; HGNC ID: 3518 |
| Relate to Another Database: | SFARIGene; denovo-db |
- Unigene ID: Hs.491354
| Pool Name | Gene EST/Total EST in pool | Transcripts per million(TPM) | Bar based on TPM |
|---|---|---|---|
 | |||
| embryoid body | 7 / 70761 | 98 |  |
| blastocyst | 8 / 62319 | 128 | |
| fetus | 39 / 564012 | 69 | |
| neonate | 0 / 31097 | 0 | |
| infant | 0 / 23620 | 0 | |
| juvenile | 1 / 55556 | 17 |  |
| adult | 117 / 1939121 | 60 | |
| Pool Name | Gene EST/Total EST in pool | Transcripts per million(TPM) | Bar based on TPM |
|---|---|---|---|
| |||
| adrenal tumor | 0 / 12794 | 0 | |
| bladder carcinoma | 1 / 17475 | 57 | |
| breast (mammary gland) tumor | 3 / 94178 | 31 | |
| cervical tumor | 0 / 34366 | 0 | |
| chondrosarcoma | 4 / 82823 | 48 | |
| colorectal tumor | 6 / 114246 | 52 | |
| esophageal tumor | 0 / 17290 | 0 | |
| gastrointestinal tumor | 21 / 119369 | 175 | |
| germ cell tumor | 37 / 263845 | 140 | |
| glioma | 10 / 106883 | 93 | |
| head and neck tumor | 8 / 136302 | 58 | |
| kidney tumor | 5 / 68959 | 72 | |
| leukemia | 0 / 95842 | 0 | |
| liver tumor | 1 / 96359 | 10 |  |
| lung tumor | 5 / 103127 | 48 | |
| lymphoma | 0 / 71755 | 0 | |
| non-neoplasia | 2 / 97250 | 20 | |
| normal | 194 / 3360307 | 57 | |
| ovarian tumor | 1 / 76682 | 13 | |
| pancreatic tumor | 1 / 104616 | 9 | |
| primitive neuroectodermal tumor of the CNS | 13 / 125680 | 103 | |
| prostate cancer | 5 / 102680 | 48 | |
| retinoblastoma | 2 / 46356 | 43 | |
| skin tumor | 6 / 124949 | 48 | |
| soft tissue/muscle tissue tumor | 1 / 125191 | 7 | |
| uterine tumor | 6 / 90257 | 66 | |
| Pool Name | Gene EST/Total EST in pool | Transcripts per million(TPM) | Bar based on TPM |
|---|---|---|---|
| |||
| adipose tissue | 2 / 13106 | 152 | |
| adrenal gland | 0 / 33197 | 0 | |
| ascites | 10 / 40015 | 249 |  |
| bladder | 2 / 29757 | 67 | |
| blood | 1 / 123478 | 8 | |
| bone | 2 / 71655 | 27 | |
| bone marrow | 0 / 48801 | 0 | |
| brain | 84 / 1100989 | 76 | |
| cervix | 1 / 48171 | 20 | |
| connective tissue | 3 / 149255 | 20 | |
| ear | 0 / 16212 | 0 | |
| embryonic tissue | 19 / 215722 | 88 | |
| esophagus | 0 / 20209 | 0 | |
| eye | 24 / 211054 | 113 | |
| heart | 3 / 89626 | 33 | |
| intestine | 12 / 234472 | 51 | |
| kidney | 6 / 211777 | 28 | |
| larynx | 2 / 24145 | 82 | |
| liver | 1 / 207743 | 4 | |
| lung | 15 / 336974 | 44 | |
| lymph | 0 / 44270 | 0 | |
| lymph node | 1 / 91610 | 10 | |
| mammary gland | 7 / 153271 | 45 | |
| mouth | 4 / 67052 | 59 | |
| muscle | 12 / 107715 | 111 | |
| nerve | 1 / 15768 | 63 | |
| ovary | 8 / 102051 | 78 | |
| pancreas | 4 / 214812 | 18 | |
| parathyroid | 0 / 20539 | 0 | |
| pharynx | 0 / 41328 | 0 | |
| pituitary gland | 0 / 16585 | 0 | |
| placenta | 6 / 280825 | 21 | |
| prostate | 8 / 189345 | 42 | |
| salivary gland | 0 / 20155 | 0 | |
| skin | 22 / 210574 | 104 | |
| spleen | 0 / 53952 | 0 | |
| stomach | 7 / 96619 | 72 | |
| testis | 30 / 330442 | 90 | |
| thymus | 1 / 81131 | 12 | |
| thyroid | 2 / 47473 | 42 | |
| tonsil | 0 / 16999 | 0 | |
| trachea | 0 / 52413 | 0 | |
| umbilical cord | 0 / 13680 | 0 | |
| uterus | 9 / 232878 | 38 | |
| vascular | 1 / 51780 | 19 | |
- Microarray Platform: GeneAtlas U133A, gcrma
- Affymatrix Probe ID: 209202_s_at
| Cell line | Expression level | Expression bar |
|---|---|---|
| ||
| 721_B_lymphoblasts | 5.1 | |
| Adipocyte | 4.75 | |
| AdrenalCortex | 5.7 | |
| Adrenalgland | 4.15 | |
| Amygdala | 4.95 | |
| Appendix | 4.85 | |
| AtrioventricularNode | 3.6 | |
| BDCA4+_DentriticCells | 5.2 | |
| Bonemarrow | 4.7 | |
| BronchialEpithelialCells | 4.7 | |
| CD105+_Endothelial | 4.55 | |
| CD14+_Monocytes | 5.5 | |
| CD19+_BCells(neg._sel.) | 4.9 | |
| CD33+_Myeloid | 6 | |
| CD34+ | 6.25 | |
| CD4+_Tcells | 5.1 | |
| CD56+_NKCells | 8.75 | |
| CD71+_EarlyErythroid | 4.65 | |
| CD8+_Tcells | 4.55 | |
| CardiacMyocytes | 5.8 | |
| Caudatenucleus | 7 | |
| Cerebellum | 3.9 | |
| CerebellumPeduncles | 5.55 | |
| CiliaryGanglion | 3.4 | |
| CingulateCortex | 9.4 | |
| Colorectaladenocarcinoma | 4.75 | |
| DorsalRootGanglion | 3.7 | |
| FetalThyroid | 5 | |
| Fetalbrain | 6.15 | |
| Fetalliver | 4.1 | |
| Fetallung | 3.9 | |
| GlobusPallidus | 5.4 | |
| Heart | 6.3 | |
| Hypothalamus | 5.25 | |
| Kidney | 3.95 | |
| Leukemia_chronicMyelogenousK-562 | 4.3 | |
| Leukemia_promyelocytic-HL-60 | 5.55 | |
| Leukemialymphoblastic(MOLT-4) | 3.85 | |
| Liver | 6.25 | |
| Lung | 5.2 | |
| Lymphnode | 4.05 | |
| Lymphoma_burkitts(Daudi) | 6.3 | |
| Lymphoma_burkitts(Raji) | 6.65 | |
| MedullaOblongata | 8.25 | |
| OccipitalLobe | 4.35 | |
| OlfactoryBulb | 3.8 | |
| Ovary | 2.95 | |
| Pancreas | 3.8 | |
| PancreaticIslet | 5.1 | |
| ParietalLobe | 5 | |
| Pituitary | 5.6 | |
| Placenta | 5.3 | |
| Pons | 10.25 | |
| PrefrontalCortex | 6.15 | |
| Prostate | 5.6 | |
| Salivarygland | 3.8 | |
| SkeletalMuscle | 5.35 | |
| Skin | 3.7 | |
| SmoothMuscle | 5.8 | |
| Spinalcord | 6.15 | |
| SubthalamicNucleus | 13.55 | |
| SuperiorCervicalGanglion | 5.45 | |
| TemporalLobe | 7.3 | |
| Testis | 4.1 | |
| TestisGermCell | 3.9 | |
| TestisIntersitial | 3.95 | |
| TestisLeydigCell | 4.7 | |
| TestisSeminiferousTubule | 4.9 | |
| Thalamus | 14.95 | |
| Thymus | 3.75 | |
| Thyroid | 5.95 | |
| Tongue | 4.65 | |
| Tonsil | 4.15 | |
| Trachea | 4 | |
| TrigeminalGanglion | 4.85 | |
| Uterus | 3.9 | |
| UterusCorpus | 4.25 | |
| WholeBlood | 5.6 | |
| Wholebrain | 4.05 | |
| colon | 4.75 | |
| pineal_day | 7 | |
| pineal_night | 5.72 | |
| retina | 6.45 | |
| small_intestine | 4.6 | |
- Probe name: CUST_16605_PI416261804
- Donor H0351.2001
- Sex: Male Age: 24 years Race/Ethnicity: African American Handedness: Left
- Tissue Receipt Date: 7/29/2009 Serology: Pass Tissue pH :6.72 Additional Medical Information :History of asthma
- Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
- Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
| Tissue | Expression(mean ± stddev) | Expression Bar |
|---|---|---|
| Amygdala | 4.12 ± 0.66 | ![](../"images/bar_3.png"){kind=small}   |
| Basal Forebrain | 3.79 ± 0.18 | |
| Basal Part of Pons | 3.88 ± 0.63 | |
| Cerebellar Cortex | 4.17 ± 0.44 | |
| Cerebellar Nuclei | 3.72 ± 0.42 | |
| Claustrum | 3.43 ± 0.79 | |
| Epithalamus | 3.8 ± 0.72 | |
| Frontal Lobe | 4.12 ± 0.54 | |
| Globus Pallidus | 3.29 ± 0.64 | |
| Hypothalamus | 3.7 ± 0.52 | |
| Insula | 4.11 ± 0.41 | |
| Limbic Lobe | 4.12 ± 0.54 | |
| Mesencephalon | 4.08 ± 0.56 | |
| Myelencephalon | 4.03 ± 0.53 | |
| Occipital Lobe | 3.99 ± 0.45 | |
| Parietal Lobe | 4.01 ± 0.59 | |
| Pontine Tegmentum | 4.07 ± 0.53 | |
| Striatum | 3.74 ± 0.52 | |
| Subthalamus | 3.83 ± 0.63 | |
| Temporal Lobe | 4.22 ± 0.51 | |
| Thalamus | 4.11 ± 0.46 | |
| White Matter | 3.31 ± 0.63 | |
Mouse Brain ISH 
| Gene Symbol | Brain Structure ID | Brain Structure Name | Express Desity/Level (Meatured by ISH) | Express Bar |
|---|---|---|---|---|
| Extl3 | CB | Cerebellum | 3.32 | |
| 3.44 | | |||
| Extl3 | CTX | Cerebral cortex | 6.39 | |
| 4.24 | | |||
| Extl3 | HIP | Hippocampal region | 7.92 | |
| 3.46 | | |||
| Extl3 | HPF | Hippocampal formation | 7.67 | |
| 3.9 | | |||
| Extl3 | HY | Hypothalamus | 0.69 | |
| 0.68 | | |||
| Extl3 | LSX | Lateral septal complex | 0.11 | |
| 0.1 | | |||
| Extl3 | MB | Midbrain | 0.79 | |
| 0.71 | | |||
| Extl3 | MY | Medulla | 1.41 | |
| 1.12 | | |||
| Extl3 | OLF | Olfactory bulb | 10.03 | |
| 5.53 | | |||
| Extl3 | P | Pons | 0.81 | |
| 0.76 | | |||
| Extl3 | PAL | Pallidum | 0.37 | |
| 0.24 | | |||
| Extl3 | RHP | Retrohippocampal region | 7.04 | |
| 4.9 | | |||
| Extl3 | sAMY | Striatum-like amygdalar nuclei | 1.15 | |
| 0.83 | | |||
| Extl3 | STR | Striatum | 0.42 | |
| 0.28 | | |||
| Extl3 | STRd | Striatum dorsal region | 0.21 | |
| 0.16 | | |||
| Extl3 | STRv | Striatum ventral region | 0.95 | |
| 0.41 | | |||
| Extl3 | TH | Thalamus | 13.44 | |
| 13.29 | |
| Peptide Name | Peptide Lengh | Peptide Start | Peptide End | Peptide Sequence | Source |
|---|---|---|---|---|---|
| EXTL3_HUMAN_673 | 10 | 673 | 682 | EEVLMNSLER | PRIDE |