Annotation Detail for FANCD2
Basic Information Top
| Gene Symbol: | FANCD2 ( DKFZp762A223,FA-D2,FA4,FACD,FAD,FAD2,FANCD,FLJ23826 ) |
|---|---|
| Gene Full Name: | Fanconi anemia, complementation group D2 |
| Band: | 3p25.3 |
| Quick Links | Entrez ID:2177; OMIM: 227646; Uniprot ID:FACD2_HUMAN; ENSEMBL ID: ENSG00000144554; HGNC ID: 3585 |
| Relate to Another Database: | SFARIGene; denovo-db |
- Unigene ID: Hs.208388
| Pool Name | Gene EST/Total EST in pool | Transcripts per million(TPM) | Bar based on TPM |
|---|---|---|---|
 | |||
| embryoid body | 2 / 70761 | 28 |  |
| blastocyst | 1 / 62319 | 16 | |
| fetus | 18 / 564012 | 31 | |
| neonate | 0 / 31097 | 0 | |
| infant | 1 / 23620 | 42 | |
| juvenile | 1 / 55556 | 17 | |
| adult | 49 / 1939121 | 25 | |
| Pool Name | Gene EST/Total EST in pool | Transcripts per million(TPM) | Bar based on TPM |
|---|---|---|---|
| |||
| adrenal tumor | 0 / 12794 | 0 | |
| bladder carcinoma | 0 / 17475 | 0 | |
| breast (mammary gland) tumor | 4 / 94178 | 42 | |
| cervical tumor | 0 / 34366 | 0 | |
| chondrosarcoma | 4 / 82823 | 48 | |
| colorectal tumor | 5 / 114246 | 43 | |
| esophageal tumor | 0 / 17290 | 0 | |
| gastrointestinal tumor | 10 / 119369 | 83 |  |
| germ cell tumor | 16 / 263845 | 60 | |
| glioma | 1 / 106883 | 9 |  |
| head and neck tumor | 1 / 136302 | 7 | |
| kidney tumor | 1 / 68959 | 14 | |
| leukemia | 6 / 95842 | 62 | |
| liver tumor | 1 / 96359 | 10 | |
| lung tumor | 1 / 103127 | 9 | |
| lymphoma | 1 / 71755 | 13 | |
| non-neoplasia | 0 / 97250 | 0 | |
| normal | 43 / 3360307 | 12 | |
| ovarian tumor | 0 / 76682 | 0 | |
| pancreatic tumor | 0 / 104616 | 0 | |
| primitive neuroectodermal tumor of the CNS | 8 / 125680 | 63 | |
| prostate cancer | 1 / 102680 | 9 | |
| retinoblastoma | 2 / 46356 | 43 | |
| skin tumor | 0 / 124949 | 0 | |
| soft tissue/muscle tissue tumor | 1 / 125191 | 7 | |
| uterine tumor | 0 / 90257 | 0 |
| Pool Name | Gene EST/Total EST in pool | Transcripts per million(TPM) | Bar based on TPM |
|---|---|---|---|
| |||
| adipose tissue | 0 / 13106 | 0 | |
| adrenal gland | 0 / 33197 | 0 | |
| ascites | 1 / 40015 | 24 | |
| bladder | 0 / 29757 | 0 | |
| blood | 4 / 123478 | 32 | |
| bone | 3 / 71655 | 41 | |
| bone marrow | 1 / 48801 | 20 | |
| brain | 7 / 1100989 | 6 | |
| cervix | 0 / 48171 | 0 | |
| connective tissue | 2 / 149255 | 13 | |
| ear | 0 / 16212 | 0 | |
| embryonic tissue | 8 / 215722 | 37 | |
| esophagus | 0 / 20209 | 0 | |
| eye | 4 / 211054 | 18 | |
| heart | 0 / 89626 | 0 | |
| intestine | 6 / 234472 | 25 | |
| kidney | 8 / 211777 | 37 | |
| larynx | 0 / 24145 | 0 | |
| liver | 3 / 207743 | 14 | |
| lung | 2 / 336974 | 5 | |
| lymph | 1 / 44270 | 22 | |
| lymph node | 2 / 91610 | 21 | |
| mammary gland | 6 / 153271 | 39 | |
| mouth | 0 / 67052 | 0 | |
| muscle | 0 / 107715 | 0 | |
| nerve | 0 / 15768 | 0 | |
| ovary | 1 / 102051 | 9 | |
| pancreas | 0 / 214812 | 0 | |
| parathyroid | 0 / 20539 | 0 | |
| pharynx | 0 / 41328 | 0 | |
| pituitary gland | 0 / 16585 | 0 | |
| placenta | 2 / 280825 | 7 | |
| prostate | 4 / 189345 | 21 | |
| salivary gland | 0 / 20155 | 0 | |
| skin | 0 / 210574 | 0 | |
| spleen | 0 / 53952 | 0 | |
| stomach | 9 / 96619 | 93 | |
| testis | 14 / 330442 | 42 | |
| thymus | 3 / 81131 | 36 | |
| thyroid | 1 / 47473 | 21 | |
| tonsil | 0 / 16999 | 0 | |
| trachea | 0 / 52413 | 0 | |
| umbilical cord | 0 / 13680 | 0 | |
| uterus | 0 / 232878 | 0 | |
| vascular | 4 / 51780 | 77 | |
Microarray in - Probe name: A_23_P345678
- Donor H0351.2001
- Sex: Male Age: 24 years Race/Ethnicity: African American Handedness: Left
- Tissue Receipt Date: 7/29/2009 Serology: Pass Tissue pH :6.72 Additional Medical Information :History of asthma
- Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
- Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
| Tissue | Expression(mean ± stddev) | Expression Bar |
|---|---|---|
| Amygdala | 2.12 ± 1.01 | ![](../"images/bar_3.png"){kind=small}   |
| Basal Forebrain | 1.67 ± 0.2 | |
| Basal Part of Pons | 1.35 ± 0.39 | |
| Cerebellar Cortex | 1.5 ± 0.73 | |
| Cerebellar Nuclei | 1.96 ± 0.74 | |
| Claustrum | 2.59 ± 0.91 | |
| Epithalamus | 1.55 ± 1.07 | |
| Frontal Lobe | 1.49 ± 0.56 | |
| Globus Pallidus | 2.29 ± 0.34 | |
| Hypothalamus | 1.77 ± 0.69 | |
| Insula | 1.53 ± 0.49 | |
| Limbic Lobe | 1.68 ± 0.62 | |
| Mesencephalon | 1.78 ± 0.66 | |
| Myelencephalon | 1.69 ± 0.65 | |
| Occipital Lobe | 1.72 ± 0.6 | |
| Parietal Lobe | 1.76 ± 0.9 | |
| Pontine Tegmentum | 1.76 ± 0.73 | |
| Striatum | 1.79 ± 0.47 | |
| Subthalamus | 1.8 ± 0.63 | |
| Temporal Lobe | 1.56 ± 0.65 | |
| Thalamus | 1.62 ± 0.56 | |
| White Matter | 2.24 ± 0.37 | |
Mouse Brain ISH 
| Gene Symbol | Brain Structure ID | Brain Structure Name | Express Desity/Level (Meatured by ISH) | Express Bar |
|---|---|---|---|---|
| Fancd2 | CB | Cerebellum | 0.7 | |
| 0.81 | | |||
| Fancd2 | CTX | Cerebral cortex | 3.5 | |
| 2.83 | | |||
| Fancd2 | HIP | Hippocampal region | 3.27 | |
| 3.58 | | |||
| Fancd2 | HPF | Hippocampal formation | 4.76 | |
| 4.21 | | |||
| Fancd2 | HY | Hypothalamus | 0.42 | |
| 0.39 | | |||
| Fancd2 | LSX | Lateral septal complex | 0.62 | |
| 0.87 | | |||
| Fancd2 | MB | Midbrain | 0.34 | |
| 0.52 | | |||
| Fancd2 | MY | Medulla | 0.46 | |
| 0.75 | | |||
| Fancd2 | OLF | Olfactory bulb | 1.63 | |
| 2.14 | | |||
| Fancd2 | P | Pons | 0.16 | |
| 0.19 | | |||
| Fancd2 | PAL | Pallidum | 0.72 | |
| 0.58 | | |||
| Fancd2 | RHP | Retrohippocampal region | 7.07 | |
| 5.01 | | |||
| Fancd2 | sAMY | Striatum-like amygdalar nuclei | 0.52 | |
| 0.41 | | |||
| Fancd2 | STR | Striatum | 1.08 | |
| 0.92 | | |||
| Fancd2 | STRd | Striatum dorsal region | 1.4 | |
| 1.19 | | |||
| Fancd2 | STRv | Striatum ventral region | 0.42 | |
| 0.26 | | |||
| Fancd2 | TH | Thalamus | 0.43 | |
| 0.48 | |
| Peptide Name | Peptide Lengh | Peptide Start | Peptide End | Peptide Sequence | Source |
|---|---|---|---|---|---|
| PAp00079477 | 13 | 914 | 926 | TSLLLHNSHAFFR | Peptide Atlas |