AutismKB 2.0

Annotation Detail for FAT1


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Basic Information Top
Gene Symbol:FAT1 ( CDHF7,CDHR8,FAT,ME5,hFat1 )
Gene Full Name: FAT tumor suppressor homolog 1 (Drosophila)
Band: 4q35.2
Quick LinksEntrez ID:2195; OMIM: 600976; Uniprot ID:FAT1_HUMAN; ENSEMBL ID: ENSG00000083857; HGNC ID: 3595
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body13 / 70761183
blastocyst15 / 62319240
fetus30 / 56401253
neonate0 / 310970 
infant0 / 236200 
juvenile8 / 55556143
adult174 / 193912189
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor1 / 1279478
bladder carcinoma1 / 1747557
breast (mammary gland) tumor23 / 94178244
cervical tumor0 / 343660 
chondrosarcoma10 / 82823120
colorectal tumor27 / 114246236
esophageal tumor5 / 17290289
gastrointestinal tumor10 / 11936983
germ cell tumor8 / 26384530
glioma9 / 10688384
head and neck tumor16 / 136302117
kidney tumor0 / 689590 
leukemia12 / 95842125
liver tumor8 / 9635983
lung tumor5 / 10312748
lymphoma0 / 717550 
non-neoplasia3 / 9725030
normal179 / 336030753
ovarian tumor1 / 7668213
pancreatic tumor6 / 10461657
primitive neuroectodermal tumor of the CNS1 / 1256807
prostate cancer8 / 10268077
retinoblastoma0 / 463560 
skin tumor2 / 12494916
soft tissue/muscle tissue tumor3 / 12519123
uterine tumor6 / 9025766
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue2 / 13106152
adrenal gland1 / 3319730
ascites0 / 400150 
bladder2 / 2975767
blood9 / 12347872
bone7 / 7165597
bone marrow2 / 4880140
brain37 / 110098933
cervix0 / 481710 
connective tissue8 / 14925553
ear2 / 16212123
embryonic tissue37 / 215722171
esophagus5 / 20209247
eye12 / 21105456
heart4 / 8962644
intestine44 / 234472187
kidney15 / 21177770
larynx4 / 24145165
liver11 / 20774352
lung33 / 33697497
lymph0 / 442700 
lymph node0 / 916100 
mammary gland33 / 153271215
mouth7 / 67052104
muscle7 / 10771564
nerve4 / 15768253
ovary3 / 10205129
pancreas11 / 21481251
parathyroid0 / 205390 
pharynx3 / 4132872
pituitary gland0 / 165850 
placenta6 / 28082521
prostate15 / 18934579
salivary gland0 / 201550 
skin3 / 21057414
spleen0 / 539520 
stomach14 / 96619144
testis8 / 33044224
thymus0 / 811310 
thyroid4 / 4747384
tonsil0 / 169990 
trachea0 / 524130 
umbilical cord0 / 136800 
uterus8 / 23287834
vascular4 / 5178077
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 201579_at
Cell line Expression level Expression bar
721_B_lymphoblasts30.65
Adipocyte211.45
AdrenalCortex21
Adrenalgland12.3
Amygdala62.5
Appendix29.05
AtrioventricularNode19.45
BDCA4+_DentriticCells10.65
Bonemarrow16.05
BronchialEpithelialCells1242.45
CD105+_Endothelial14.2
CD14+_Monocytes11.55
CD19+_BCells(neg._sel.)14.3
CD33+_Myeloid12.65
CD34+14.45
CD4+_Tcells12.35
CD56+_NKCells12.1
CD71+_EarlyErythroid13.5
CD8+_Tcells9.85
CardiacMyocytes56.75
Caudatenucleus40.95
Cerebellum53.9
CerebellumPeduncles81.1
CiliaryGanglion29.5
CingulateCortex25.8
Colorectaladenocarcinoma99.55
DorsalRootGanglion20.75
FetalThyroid56.35
Fetalbrain25.6
Fetalliver30.3
Fetallung162.9
GlobusPallidus14.25
Heart16.8
Hypothalamus138.3
Kidney151.3
Leukemia_chronicMyelogenousK-56214.45
Leukemia_promyelocytic-HL-6014.45
Leukemialymphoblastic(MOLT-4)833.45
Liver18.3
Lung45.9
Lymphnode14.05
Lymphoma_burkitts(Daudi)19.75
Lymphoma_burkitts(Raji)21.6
MedullaOblongata29.35
OccipitalLobe44.8
OlfactoryBulb83.8
Ovary11.65
Pancreas64.2
PancreaticIslet27.7
ParietalLobe30.6
Pituitary51.25
Placenta40.75
Pons24.55
PrefrontalCortex86.5
Prostate239.35
Salivarygland39.8
SkeletalMuscle18.8
Skin20.8
SmoothMuscle155.05
Spinalcord168.35
SubthalamicNucleus15.1
SuperiorCervicalGanglion30.85
TemporalLobe17.6
Testis36.75
TestisGermCell76.05
TestisIntersitial26.85
TestisLeydigCell28.3
TestisSeminiferousTubule38.4
Thalamus47.75
Thymus16.65
Thyroid69
Tongue20.65
Tonsil16.1
Trachea26.1
TrigeminalGanglion17.05
Uterus91.2
UterusCorpus17.5
WholeBlood11.3
Wholebrain26.4
colon299.3
pineal_day24.04
pineal_night29.9
retina103.175
small_intestine256.3
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: CUST_14444_PI416261804
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala4.7 ± 0.69
Basal Forebrain4.83 ± 0.36
Basal Part of Pons3.64 ± 0.45
Cerebellar Cortex4.71 ± 0.55
Cerebellar Nuclei4.98 ± 0.72
Claustrum4.39 ± 1
Epithalamus5.38 ± 0.32
Frontal Lobe4.25 ± 0.69
Globus Pallidus5.63 ± 0.61
Hypothalamus4.67 ± 0.46
Insula4.12 ± 0.63
Limbic Lobe4.07 ± 0.75
Mesencephalon4.71 ± 0.68
Myelencephalon4.5 ± 0.72
Occipital Lobe4.51 ± 0.62
Parietal Lobe4.35 ± 0.77
Pontine Tegmentum4.53 ± 0.65
Striatum4.53 ± 0.72
Subthalamus3.97 ± 0.22
Temporal Lobe4.12 ± 0.63
Thalamus4.66 ± 0.52
White Matter5.85 ± 0.74
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
FathCBCerebellum14.16
14.97
FathCTXCerebral cortex38.97
30.51
FathHIPHippocampal region11.84
12.54
FathHPFHippocampal formation24.6
22.83
FathHYHypothalamus8.47
7.02
FathLSXLateral septal complex0.47
0.34
FathMBMidbrain11.67
10.65
FathMYMedulla18.61
18.76
FathOLFOlfactory bulb46.98
40.74
FathPPons15.57
15.38
FathPALPallidum11.36
9.9
FathRHPRetrohippocampal region48.84
39.44
FathsAMYStriatum-like amygdalar nuclei18.45
13.35
FathSTRStriatum12.56
9.14
FathSTRdStriatum dorsal region14.6
10.98
FathSTRvStriatum ventral region5.79
3.35
FathTHThalamus8.34
7.11
Peptide Top
Peptide Name Peptide Lengh Peptide Start Peptide End Peptide Sequence Source
PAp00040697 18 2437 2454 HFVIDSATGIITLSNLHR Peptide Atlas

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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