AutismKB 2.0

Annotation Detail for FAT2


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Basic Information Top
Gene Symbol:FAT2 ( CDHF8,CDHR9,HFAT2,MEGF1 )
Gene Full Name: FAT tumor suppressor homolog 2 (Drosophila)
Band: 5q33.1
Quick LinksEntrez ID:2196; OMIM: 604269; Uniprot ID:FAT2_HUMAN; ENSEMBL ID: ENSG00000086570; HGNC ID: 3596
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body0 / 707610 
blastocyst0 / 623190 
fetus3 / 5640125
neonate0 / 310970 
infant1 / 2362042
juvenile0 / 555560 
adult24 / 193912112
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma1 / 1747557
breast (mammary gland) tumor0 / 941780 
cervical tumor0 / 343660 
chondrosarcoma0 / 828230 
colorectal tumor0 / 1142460 
esophageal tumor1 / 1729057
gastrointestinal tumor0 / 1193690 
germ cell tumor0 / 2638450 
glioma1 / 1068839
head and neck tumor9 / 13630266
kidney tumor0 / 689590 
leukemia0 / 958420 
liver tumor0 / 963590 
lung tumor2 / 10312719
lymphoma0 / 717550 
non-neoplasia1 / 9725010
normal45 / 336030713
ovarian tumor6 / 7668278
pancreatic tumor5 / 10461647
primitive neuroectodermal tumor of the CNS0 / 1256800 
prostate cancer1 / 1026809
retinoblastoma0 / 463560 
skin tumor5 / 12494940
soft tissue/muscle tissue tumor0 / 1251910 
uterine tumor2 / 9025722
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland0 / 331970 
ascites0 / 400150 
bladder1 / 2975733
blood0 / 1234780 
bone0 / 716550 
bone marrow0 / 488010 
brain18 / 110098916
cervix0 / 481710 
connective tissue0 / 1492550 
ear0 / 162120 
embryonic tissue0 / 2157220 
esophagus1 / 2020949
eye1 / 2110544
heart0 / 896260 
intestine0 / 2344720 
kidney1 / 2117774
larynx1 / 2414541
liver0 / 2077430 
lung6 / 33697417
lymph0 / 442700 
lymph node0 / 916100 
mammary gland1 / 1532716
mouth8 / 67052119
muscle4 / 10771537
nerve0 / 157680 
ovary6 / 10205158
pancreas5 / 21481223
parathyroid3 / 20539146
pharynx0 / 413280 
pituitary gland1 / 1658560
placenta2 / 2808257
prostate1 / 1893455
salivary gland0 / 201550 
skin5 / 21057423
spleen0 / 539520 
stomach0 / 966190 
testis3 / 3304429
thymus2 / 8113124
thyroid0 / 474730 
tonsil0 / 169990 
trachea0 / 524130 
umbilical cord0 / 136800 
uterus2 / 2328788
vascular0 / 517800 
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 208153_s_at
Cell line Expression level Expression bar
721_B_lymphoblasts6.1
Adipocyte5.05
AdrenalCortex11.25
Adrenalgland4.35
Amygdala5.5
Appendix5.45
AtrioventricularNode4.05
BDCA4+_DentriticCells5.6
Bonemarrow5.3
BronchialEpithelialCells14.6
CD105+_Endothelial5.2
CD14+_Monocytes5.2
CD19+_BCells(neg._sel.)5.05
CD33+_Myeloid6.5
CD34+6.45
CD4+_Tcells5.35
CD56+_NKCells5.5
CD71+_EarlyErythroid4.85
CD8+_Tcells4.75
CardiacMyocytes6.45
Caudatenucleus4.65
Cerebellum297.2
CerebellumPeduncles310.55
CiliaryGanglion3.65
CingulateCortex5.35
Colorectaladenocarcinoma5.15
DorsalRootGanglion4.15
FetalThyroid4.95
Fetalbrain5
Fetalliver4.5
Fetallung4.05
GlobusPallidus3.75
Heart7.2
Hypothalamus5.45
Kidney4.35
Leukemia_chronicMyelogenousK-5624.7
Leukemia_promyelocytic-HL-604.55
Leukemialymphoblastic(MOLT-4)4.1
Liver7.2
Lung5.8
Lymphnode4.3
Lymphoma_burkitts(Daudi)6.7
Lymphoma_burkitts(Raji)7.3
MedullaOblongata4.6
OccipitalLobe4.55
OlfactoryBulb4
Ovary3.4
Pancreas4.1
PancreaticIslet5.45
ParietalLobe8.6
Pituitary6
Placenta5.65
Pons5
PrefrontalCortex6.4
Prostate6.15
Salivarygland4.25
SkeletalMuscle8.95
Skin4.15
SmoothMuscle5.8
Spinalcord5.65
SubthalamicNucleus4.75
SuperiorCervicalGanglion6.25
TemporalLobe4.75
Testis4.7
TestisGermCell4.3
TestisIntersitial4.4
TestisLeydigCell5.35
TestisSeminiferousTubule4.45
Thalamus5.25
Thymus4.15
Thyroid6.35
Tongue5.35
Tonsil5.2
Trachea6.7
TrigeminalGanglion5.45
Uterus4.2
UterusCorpus4.75
WholeBlood5.55
Wholebrain4.15
colon5.15
pineal_day6.28
pineal_night6.2
retina6.2
small_intestine5
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: CUST_2403_PI416261804
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala3.37 ± 0.99
Basal Forebrain2.91 ± 0.64
Basal Part of Pons4.28 ± 0.73
Cerebellar Cortex4.05 ± 0.62
Cerebellar Nuclei3.04 ± 0.53
Claustrum3.93 ± 1.06
Epithalamus2.32 ± 1.08
Frontal Lobe2.9 ± 0.89
Globus Pallidus2.78 ± 1.05
Hypothalamus3.04 ± 0.55
Insula2.67 ± 0.85
Limbic Lobe2.95 ± 0.79
Mesencephalon3.01 ± 0.77
Myelencephalon3.14 ± 0.87
Occipital Lobe3.18 ± 0.98
Parietal Lobe3.06 ± 0.9
Pontine Tegmentum2.58 ± 0.66
Striatum2.95 ± 0.92
Subthalamus2.95 ± 0.65
Temporal Lobe2.82 ± 0.96
Thalamus2.99 ± 0.74
White Matter2.59 ± 0.22
Mouse Brain ISH
Peptide Top
Peptide Name Peptide Lengh Peptide Start Peptide End Peptide Sequence Source
FAT2_HUMAN_2803 25 2803 2827 AVLTENMPVGTSVIQVTAIDKDTGR PRIDE

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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