AutismKB 2.0

Annotation Detail for TBCEL


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Basic Information Top
Gene Symbol:TBCEL ( El,FLJ14177,LRRC35,MGC10233 )
Gene Full Name: tubulin folding cofactor E-like
Band: 11q23.3
Quick LinksEntrez ID:219899; OMIM: 610451; Uniprot ID:TBCEL_HUMAN; ENSEMBL ID: ENSG00000154114; HGNC ID: 28115
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body2 / 7076128
blastocyst2 / 6231932
fetus9 / 56401215
neonate0 / 310970 
infant0 / 236200 
juvenile1 / 5555617
adult36 / 193912118
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma0 / 174750 
breast (mammary gland) tumor1 / 9417810
cervical tumor1 / 3436629
chondrosarcoma2 / 8282324
colorectal tumor0 / 1142460 
esophageal tumor1 / 1729057
gastrointestinal tumor3 / 11936925
germ cell tumor6 / 26384522
glioma0 / 1068830 
head and neck tumor2 / 13630214
kidney tumor0 / 689590 
leukemia1 / 9584210
liver tumor1 / 9635910
lung tumor0 / 1031270 
lymphoma4 / 7175555
non-neoplasia1 / 9725010
normal45 / 336030713
ovarian tumor0 / 766820 
pancreatic tumor1 / 1046169
primitive neuroectodermal tumor of the CNS1 / 1256807
prostate cancer0 / 1026800 
retinoblastoma0 / 463560 
skin tumor1 / 1249498
soft tissue/muscle tissue tumor1 / 1251917
uterine tumor2 / 9025722
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland0 / 331970 
ascites0 / 400150 
bladder1 / 2975733
blood3 / 12347824
bone3 / 7165541
bone marrow1 / 4880120
brain10 / 11009899
cervix3 / 4817162
connective tissue1 / 1492556
ear0 / 162120 
embryonic tissue5 / 21572223
esophagus1 / 2020949
eye3 / 21105414
heart4 / 8962644
intestine0 / 2344720 
kidney2 / 2117779
larynx0 / 241450 
liver2 / 2077439
lung2 / 3369745
lymph0 / 442700 
lymph node1 / 9161010
mammary gland1 / 1532716
mouth0 / 670520 
muscle3 / 10771527
nerve0 / 157680 
ovary0 / 1020510 
pancreas3 / 21481213
parathyroid3 / 20539146
pharynx0 / 413280 
pituitary gland0 / 165850 
placenta6 / 28082521
prostate3 / 18934515
salivary gland0 / 201550 
skin1 / 2105744
spleen0 / 539520 
stomach3 / 9661931
testis11 / 33044233
thymus0 / 811310 
thyroid2 / 4747342
tonsil0 / 169990 
trachea1 / 5241319
umbilical cord0 / 136800 
uterus6 / 23287825
vascular2 / 5178038
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 222365_at
Cell line Expression level Expression bar
721_B_lymphoblasts5.5
Adipocyte4.45
AdrenalCortex4.8
Adrenalgland3.85
Amygdala4.65
Appendix6.15
AtrioventricularNode3.65
BDCA4+_DentriticCells4.75
Bonemarrow4.7
BronchialEpithelialCells4.45
CD105+_Endothelial4.5
CD14+_Monocytes4.75
CD19+_BCells(neg._sel.)4.7
CD33+_Myeloid5.65
CD34+5.8
CD4+_Tcells4.8
CD56+_NKCells5.3
CD71+_EarlyErythroid5.85
CD8+_Tcells4.3
CardiacMyocytes6.55
Caudatenucleus4.05
Cerebellum3.75
CerebellumPeduncles5.15
CiliaryGanglion3.35
CingulateCortex4.7
Colorectaladenocarcinoma4.55
DorsalRootGanglion3.55
FetalThyroid4.4
Fetalbrain4.55
Fetalliver4.05
Fetallung3.85
GlobusPallidus3.35
Heart6.15
Hypothalamus4.85
Kidney3.95
Leukemia_chronicMyelogenousK-5624.1
Leukemia_promyelocytic-HL-604.05
Leukemialymphoblastic(MOLT-4)3.65
Liver6.4
Lung5
Lymphnode3.85
Lymphoma_burkitts(Daudi)5.85
Lymphoma_burkitts(Raji)6.45
MedullaOblongata4.2
OccipitalLobe4.05
OlfactoryBulb3.6
Ovary3
Pancreas3.65
PancreaticIslet4.9
ParietalLobe4.9
Pituitary5.3
Placenta4.55
Pons4.4
PrefrontalCortex5.6
Prostate5.2
Salivarygland3.7
SkeletalMuscle5.6
Skin3.6
SmoothMuscle5.05
Spinalcord5.1
SubthalamicNucleus4.15
SuperiorCervicalGanglion5.45
TemporalLobe4.25
Testis3.9
TestisGermCell3.8
TestisIntersitial3.75
TestisLeydigCell4.5
TestisSeminiferousTubule3.85
Thalamus4.7
Thymus3.45
Thyroid5.55
Tongue4.45
Tonsil4.45
Trachea3.85
TrigeminalGanglion5.45
Uterus3.7
UterusCorpus4.3
WholeBlood4.9
Wholebrain3.8
colon4.5
pineal_day5.64
pineal_night5.5
retina5.425
small_intestine4.35
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: A_23_P410017
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala7.25 ± 0.28
Basal Forebrain7.52 ± 0.11
Basal Part of Pons7.4 ± 0.18
Cerebellar Cortex7.67 ± 0.19
Cerebellar Nuclei7.71 ± 0.23
Claustrum7.43 ± 0.35
Epithalamus7.94 ± 0.22
Frontal Lobe7.47 ± 0.23
Globus Pallidus7.66 ± 0.19
Hypothalamus7.54 ± 0.18
Insula7.43 ± 0.28
Limbic Lobe7.5 ± 0.29
Mesencephalon7.62 ± 0.28
Myelencephalon7.51 ± 0.27
Occipital Lobe7.83 ± 0.29
Parietal Lobe7.55 ± 0.24
Pontine Tegmentum7.57 ± 0.23
Striatum7.45 ± 0.24
Subthalamus7.65 ± 0.11
Temporal Lobe7.43 ± 0.24
Thalamus7.49 ± 0.29
White Matter8.11 ± 0.13
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Lrrc35CBCerebellum13.72
16.77
Lrrc35CTXCerebral cortex11.61
8.09
Lrrc35HIPHippocampal region17.62
17.73
Lrrc35HPFHippocampal formation15.34
14.02
Lrrc35HYHypothalamus3.05
2.3
Lrrc35LSXLateral septal complex1.72
1.25
Lrrc35MBMidbrain4.22
4.73
Lrrc35MYMedulla12.49
15.09
Lrrc35OLFOlfactory bulb3.89
3.87
Lrrc35PPons6.84
7.42
Lrrc35PALPallidum4.37
3.88
Lrrc35RHPRetrohippocampal region10.53
7.86
Lrrc35sAMYStriatum-like amygdalar nuclei3.73
3.01
Lrrc35STRStriatum4.93
3.63
Lrrc35STRdStriatum dorsal region5.37
4.03
Lrrc35STRvStriatum ventral region5.61
3.73
Lrrc35THThalamus8.75
7.1
Peptide Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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