AutismKB 2.0

Annotation Detail for OAF


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Basic Information Top
Gene Symbol:OAF ( MGC52117,NS5ATP13TP2 )
Gene Full Name: OAF homolog (Drosophila)
Band: 11q23.3
Quick LinksEntrez ID:220323; OMIM: NA; Uniprot ID:OAF_HUMAN; ENSEMBL ID: ENSG00000184232; HGNC ID: 28752
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body0 / 707610 
blastocyst0 / 623190 
fetus10 / 56401217
neonate0 / 310970 
infant0 / 236200 
juvenile1 / 5555617
adult125 / 193912164
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma0 / 174750 
breast (mammary gland) tumor6 / 9417863
cervical tumor1 / 3436629
chondrosarcoma4 / 8282348
colorectal tumor14 / 114246122
esophageal tumor1 / 1729057
gastrointestinal tumor4 / 11936933
germ cell tumor2 / 2638457
glioma6 / 10688356
head and neck tumor1 / 1363027
kidney tumor2 / 6895929
leukemia2 / 9584220
liver tumor40 / 96359415
lung tumor3 / 10312729
lymphoma3 / 7175541
non-neoplasia1 / 9725010
normal92 / 336030727
ovarian tumor0 / 766820 
pancreatic tumor8 / 10461676
primitive neuroectodermal tumor of the CNS19 / 125680151
prostate cancer3 / 10268029
retinoblastoma0 / 463560 
skin tumor4 / 12494932
soft tissue/muscle tissue tumor2 / 12519115
uterine tumor9 / 9025799
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland0 / 331970 
ascites0 / 400150 
bladder1 / 2975733
blood5 / 12347840
bone2 / 7165527
bone marrow1 / 4880120
brain20 / 110098918
cervix5 / 48171103
connective tissue4 / 14925526
ear3 / 16212185
embryonic tissue4 / 21572218
esophagus1 / 2020949
eye13 / 21105461
heart1 / 8962611
intestine18 / 23447276
kidney10 / 21177747
larynx0 / 241450 
liver46 / 207743221
lung8 / 33697423
lymph2 / 4427045
lymph node1 / 9161010
mammary gland6 / 15327139
mouth0 / 670520 
muscle2 / 10771518
nerve1 / 1576863
ovary2 / 10205119
pancreas9 / 21481241
parathyroid0 / 205390 
pharynx0 / 413280 
pituitary gland0 / 165850 
placenta10 / 28082535
prostate4 / 18934521
salivary gland0 / 201550 
skin6 / 21057428
spleen2 / 5395237
stomach4 / 9661941
testis0 / 3304420 
thymus1 / 8113112
thyroid1 / 4747321
tonsil0 / 169990 
trachea0 / 524130 
umbilical cord0 / 136800 
uterus12 / 23287851
vascular0 / 517800 
Microarray in BioGPS Top
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: A_23_P310590
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala3.02 ± 0.81
Basal Forebrain2.75 ± 0.44
Basal Part of Pons2.39 ± 0.41
Cerebellar Cortex2.15 ± 0.4
Cerebellar Nuclei2.86 ± 0.56
Claustrum2.88 ± 0.61
Epithalamus2.42 ± 0.91
Frontal Lobe2.75 ± 0.68
Globus Pallidus2.04 ± 0.63
Hypothalamus2.41 ± 0.76
Insula2.82 ± 0.74
Limbic Lobe2.76 ± 0.68
Mesencephalon2.84 ± 0.8
Myelencephalon2.77 ± 0.69
Occipital Lobe2.68 ± 0.71
Parietal Lobe2.84 ± 0.88
Pontine Tegmentum2.88 ± 0.76
Striatum4.03 ± 0.45
Subthalamus2.76 ± 0.82
Temporal Lobe2.78 ± 0.64
Thalamus2.62 ± 0.68
White Matter1.86 ± 0.15
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
OafCBCerebellum86.78
100
OafCTXCerebral cortex100
100
OafHIPHippocampal region100
100
OafHPFHippocampal formation100
100
OafHYHypothalamus100
100
OafLSXLateral septal complex100
100
OafMBMidbrain100
100
OafMYMedulla45.37
61
OafOLFOlfactory bulb100
100
OafPPons71.69
80.05
OafPALPallidum100
100
OafRHPRetrohippocampal region100
100
OafsAMYStriatum-like amygdalar nuclei100
100
OafSTRStriatum100
100
OafSTRdStriatum dorsal region100
100
OafSTRvStriatum ventral region100
100
OafTHThalamus100
100
Peptide Top
Peptide Name Peptide Lengh Peptide Start Peptide End Peptide Sequence Source
PAp00092524 17 178 194 FWLEQGVDSSVFEALPK Peptide Atlas

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018