AutismKB 2.0

Annotation Detail for MARCH8


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Basic Information Top
Gene Symbol:MARCH8 ( MARCH-VIII,MIR,RNF178,c-MIR )
Gene Full Name: membrane-associated ring finger (C3HC4) 8
Band: 10q11.21
Quick LinksEntrez ID:220972; OMIM: 613335; Uniprot ID:MARH8_HUMAN; ENSEMBL ID: ENSG00000165406; HGNC ID:
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body2 / 7076128
blastocyst0 / 623190 
fetus32 / 56401256
neonate0 / 310970 
infant0 / 236200 
juvenile0 / 555560 
adult76 / 193912139
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma0 / 174750 
breast (mammary gland) tumor0 / 941780 
cervical tumor2 / 3436658
chondrosarcoma5 / 8282360
colorectal tumor3 / 11424626
esophageal tumor1 / 1729057
gastrointestinal tumor1 / 1193698
germ cell tumor2 / 2638457
glioma5 / 10688346
head and neck tumor3 / 13630222
kidney tumor0 / 689590 
leukemia18 / 95842187
liver tumor3 / 9635931
lung tumor0 / 1031270 
lymphoma3 / 7175541
non-neoplasia4 / 9725041
normal150 / 336030744
ovarian tumor5 / 7668265
pancreatic tumor7 / 10461666
primitive neuroectodermal tumor of the CNS0 / 1256800 
prostate cancer0 / 1026800 
retinoblastoma2 / 4635643
skin tumor3 / 12494924
soft tissue/muscle tissue tumor2 / 12519115
uterine tumor1 / 9025711
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue2 / 13106152
adrenal gland0 / 331970 
ascites1 / 4001524
bladder0 / 297570 
blood6 / 12347848
bone4 / 7165555
bone marrow9 / 48801184
brain30 / 110098927
cervix2 / 4817141
connective tissue2 / 14925513
ear0 / 162120 
embryonic tissue2 / 2157229
esophagus1 / 2020949
eye17 / 21105480
heart1 / 8962611
intestine7 / 23447229
kidney5 / 21177723
larynx1 / 2414541
liver6 / 20774328
lung4 / 33697411
lymph2 / 4427045
lymph node15 / 91610163
mammary gland1 / 1532716
mouth2 / 6705229
muscle3 / 10771527
nerve0 / 157680 
ovary6 / 10205158
pancreas15 / 21481269
parathyroid2 / 2053997
pharynx1 / 4132824
pituitary gland1 / 1658560
placenta6 / 28082521
prostate1 / 1893455
salivary gland0 / 201550 
skin3 / 21057414
spleen0 / 539520 
stomach8 / 9661982
testis48 / 330442145
thymus3 / 8113136
thyroid0 / 474730 
tonsil1 / 1699958
trachea0 / 524130 
umbilical cord0 / 136800 
uterus12 / 23287851
vascular1 / 5178019
Microarray in BioGPS Top
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: CUST_5076_PI416261804
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala5.82 ± 0.36
Basal Forebrain6.25 ± 0.18
Basal Part of Pons5.84 ± 0.38
Cerebellar Cortex6.45 ± 0.22
Cerebellar Nuclei5.96 ± 0.25
Claustrum5.97 ± 0.37
Epithalamus6.3 ± 0.42
Frontal Lobe6.1 ± 0.44
Globus Pallidus6.59 ± 0.46
Hypothalamus6.19 ± 0.38
Insula6.14 ± 0.3
Limbic Lobe6.01 ± 0.54
Mesencephalon6.13 ± 0.48
Myelencephalon6.1 ± 0.46
Occipital Lobe5.77 ± 0.35
Parietal Lobe5.88 ± 0.43
Pontine Tegmentum6.05 ± 0.43
Striatum5.99 ± 0.4
Subthalamus5.94 ± 0.56
Temporal Lobe6.02 ± 0.36
Thalamus6.09 ± 0.4
White Matter7.34 ± 0.34
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
March8CBCerebellum31.49
35.87
March8CTXCerebral cortex27.54
20.74
March8HIPHippocampal region28.28
28.64
March8HPFHippocampal formation24.66
22.87
March8HYHypothalamus38.83
30.1
March8LSXLateral septal complex10.11
8.98
March8MBMidbrain28.39
24.11
March8MYMedulla49.75
46.97
March8OLFOlfactory bulb43.26
36.59
March8PPons41.47
37.8
March8PALPallidum26.7
23
March8RHPRetrohippocampal region16.37
13.07
March8sAMYStriatum-like amygdalar nuclei34.88
24.64
March8STRStriatum16.1
12.87
March8STRdStriatum dorsal region15.19
12.86
March8STRvStriatum ventral region11.56
8.12
March8THThalamus27.49
23.14
Peptide Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018