AutismKB 2.0

Annotation Detail for ALKBH3


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Basic Information Top
Gene Symbol:ALKBH3 ( ABH3,DEPC-1,DEPC1,FLJ43614,MGC118790,MGC118792,MGC118793,PCA1 )
Gene Full Name: alkB, alkylation repair homolog 3 (E. coli)
Band: 11p11.2
Quick LinksEntrez ID:221120; OMIM: 610603; Uniprot ID:ALKB3_HUMAN; ENSEMBL ID: ENSG00000166199; HGNC ID: 30141
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body2 / 7076128
blastocyst3 / 6231948
fetus9 / 56401215
neonate2 / 3109764
infant2 / 2362084
juvenile1 / 5555617
adult67 / 193912134
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma0 / 174750 
breast (mammary gland) tumor2 / 9417821
cervical tumor2 / 3436658
chondrosarcoma5 / 8282360
colorectal tumor11 / 11424696
esophageal tumor1 / 1729057
gastrointestinal tumor3 / 11936925
germ cell tumor12 / 26384545
glioma1 / 1068839
head and neck tumor0 / 1363020 
kidney tumor2 / 6895929
leukemia2 / 9584220
liver tumor1 / 9635910
lung tumor6 / 10312758
lymphoma1 / 7175513
non-neoplasia2 / 9725020
normal88 / 336030726
ovarian tumor3 / 7668239
pancreatic tumor8 / 10461676
primitive neuroectodermal tumor of the CNS6 / 12568047
prostate cancer7 / 10268068
retinoblastoma2 / 4635643
skin tumor5 / 12494940
soft tissue/muscle tissue tumor8 / 12519163
uterine tumor0 / 902570 
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland0 / 331970 
ascites3 / 4001574
bladder1 / 2975733
blood5 / 12347840
bone3 / 7165541
bone marrow0 / 488010 
brain21 / 110098919
cervix2 / 4817141
connective tissue8 / 14925553
ear0 / 162120 
embryonic tissue8 / 21572237
esophagus2 / 2020998
eye10 / 21105447
heart1 / 8962611
intestine13 / 23447255
kidney9 / 21177742
larynx0 / 241450 
liver4 / 20774319
lung15 / 33697444
lymph1 / 4427022
lymph node0 / 916100 
mammary gland3 / 15327119
mouth0 / 670520 
muscle4 / 10771537
nerve0 / 157680 
ovary6 / 10205158
pancreas8 / 21481237
parathyroid0 / 205390 
pharynx0 / 413280 
pituitary gland0 / 165850 
placenta9 / 28082532
prostate12 / 18934563
salivary gland0 / 201550 
skin6 / 21057428
spleen5 / 5395292
stomach0 / 966190 
testis21 / 33044263
thymus2 / 8113124
thyroid0 / 474730 
tonsil0 / 169990 
trachea0 / 524130 
umbilical cord2 / 13680146
uterus4 / 23287817
vascular1 / 5178019
Microarray in BioGPS Top
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: CUST_11879_PI416261804
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala5.05 ± 0.48
Basal Forebrain4.83 ± 0.37
Basal Part of Pons5.27 ± 0.28
Cerebellar Cortex5.48 ± 0.24
Cerebellar Nuclei5.53 ± 0.46
Claustrum4.82 ± 0.66
Epithalamus5.1 ± 0.22
Frontal Lobe5.19 ± 0.39
Globus Pallidus4.92 ± 0.36
Hypothalamus4.88 ± 0.49
Insula5 ± 0.37
Limbic Lobe5.15 ± 0.5
Mesencephalon5.13 ± 0.48
Myelencephalon5.05 ± 0.48
Occipital Lobe5.11 ± 0.33
Parietal Lobe5.1 ± 0.47
Pontine Tegmentum5.12 ± 0.47
Striatum4.86 ± 0.39
Subthalamus5.5 ± 0.06
Temporal Lobe5.08 ± 0.43
Thalamus4.95 ± 0.4
White Matter5.49 ± 0.37
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Alkbh3CBCerebellum1.66
2.07
Alkbh3CTXCerebral cortex2.98
2.24
Alkbh3HIPHippocampal region5.87
5.74
Alkbh3HPFHippocampal formation5.93
5.36
Alkbh3HYHypothalamus9.75
8.21
Alkbh3LSXLateral septal complex1.99
1.56
Alkbh3MBMidbrain3.88
5.38
Alkbh3MYMedulla3.38
4.89
Alkbh3OLFOlfactory bulb10.13
7.21
Alkbh3PPons7.62
9.82
Alkbh3PALPallidum4.04
3.6
Alkbh3RHPRetrohippocampal region6.33
4.98
Alkbh3sAMYStriatum-like amygdalar nuclei4.3
3.03
Alkbh3STRStriatum1.94
1.43
Alkbh3STRdStriatum dorsal region0.63
0.47
Alkbh3STRvStriatum ventral region5.35
3.62
Alkbh3THThalamus3.63
2.68
Peptide Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018