AutismKB 2.0

Annotation Detail for CPNE2


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Basic Information Top
Gene Symbol:CPNE2 ( COPN2,CPN2,DKFZp686E06199,MGC16924 )
Gene Full Name: copine II
Band: 16q13
Quick LinksEntrez ID:221184; OMIM: 604206; Uniprot ID:CPNE2_HUMAN; ENSEMBL ID: ENSG00000140848; HGNC ID: 2315
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body4 / 7076156
blastocyst2 / 6231932
fetus22 / 56401239
neonate1 / 3109732
infant1 / 2362042
juvenile2 / 5555635
adult77 / 193912139
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma0 / 174750 
breast (mammary gland) tumor0 / 941780 
cervical tumor0 / 343660 
chondrosarcoma7 / 8282384
colorectal tumor6 / 11424652
esophageal tumor0 / 172900 
gastrointestinal tumor0 / 1193690 
germ cell tumor11 / 26384541
glioma7 / 10688365
head and neck tumor3 / 13630222
kidney tumor1 / 6895914
leukemia12 / 95842125
liver tumor1 / 9635910
lung tumor7 / 10312767
lymphoma2 / 7175527
non-neoplasia2 / 9725020
normal125 / 336030737
ovarian tumor3 / 7668239
pancreatic tumor10 / 10461695
primitive neuroectodermal tumor of the CNS3 / 12568023
prostate cancer8 / 10268077
retinoblastoma0 / 463560 
skin tumor12 / 12494996
soft tissue/muscle tissue tumor14 / 125191111
uterine tumor6 / 9025766
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland2 / 3319760
ascites0 / 400150 
bladder1 / 2975733
blood12 / 12347897
bone2 / 7165527
bone marrow3 / 4880161
brain37 / 110098933
cervix3 / 4817162
connective tissue6 / 14925540
ear2 / 16212123
embryonic tissue10 / 21572246
esophagus0 / 202090 
eye14 / 21105466
heart3 / 8962633
intestine14 / 23447259
kidney3 / 21177714
larynx1 / 2414541
liver3 / 20774314
lung18 / 33697453
lymph0 / 442700 
lymph node4 / 9161043
mammary gland1 / 1532716
mouth1 / 6705214
muscle6 / 10771555
nerve1 / 1576863
ovary5 / 10205148
pancreas12 / 21481255
parathyroid0 / 205390 
pharynx1 / 4132824
pituitary gland0 / 165850 
placenta12 / 28082542
prostate11 / 18934558
salivary gland0 / 201550 
skin12 / 21057456
spleen3 / 5395255
stomach0 / 966190 
testis9 / 33044227
thymus2 / 8113124
thyroid1 / 4747321
tonsil0 / 169990 
trachea0 / 524130 
umbilical cord1 / 1368073
uterus14 / 23287860
vascular1 / 5178019
Microarray in BioGPS Top
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: CUST_29_PI416261804
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala3.74 ± 0.54
Basal Forebrain3.55 ± 0.33
Basal Part of Pons3.22 ± 0.49
Cerebellar Cortex3.22 ± 0.69
Cerebellar Nuclei3.32 ± 0.56
Claustrum3.37 ± 0.97
Epithalamus3.84 ± 0.86
Frontal Lobe3.35 ± 0.72
Globus Pallidus4.36 ± 0.51
Hypothalamus3.69 ± 0.52
Insula2.98 ± 0.67
Limbic Lobe3.39 ± 0.76
Mesencephalon3.51 ± 0.85
Myelencephalon3.44 ± 0.66
Occipital Lobe3.11 ± 0.78
Parietal Lobe3.29 ± 0.68
Pontine Tegmentum3.39 ± 0.71
Striatum3.69 ± 0.5
Subthalamus3.33 ± 0.29
Temporal Lobe3.38 ± 0.58
Thalamus3.53 ± 0.63
White Matter5.35 ± 0.36
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Cpne2CBCerebellum62.43
100
Cpne2CTXCerebral cortex59.28
44.24
Cpne2HIPHippocampal region49.01
79.7
Cpne2HPFHippocampal formation52.45
64.74
Cpne2HYHypothalamus71.67
47.51
Cpne2LSXLateral septal complex80.68
63.66
Cpne2MBMidbrain20.13
14.13
Cpne2MYMedulla26.41
28.16
Cpne2OLFOlfactory bulb74.22
56.61
Cpne2PPons30.39
22.07
Cpne2PALPallidum56.6
45.22
Cpne2RHPRetrohippocampal region55.73
47.5
Cpne2sAMYStriatum-like amygdalar nuclei100
80.62
Cpne2STRStriatum84.81
56.64
Cpne2STRdStriatum dorsal region72.77
45.64
Cpne2STRvStriatum ventral region100
65.72
Cpne2THThalamus56.03
45.86
Peptide Top
Peptide Name Peptide Lengh Peptide Start Peptide End Peptide Sequence Source
PAp00412132 9 501 509 DIVQFVPFR Peptide Atlas

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018