AutismKB 2.0

Annotation Detail for GPR114


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Basic Information Top
Gene Symbol:GPR114 ( PGR27 )
Gene Full Name: G protein-coupled receptor 114
Band: 16q21
Quick LinksEntrez ID:221188; OMIM: NA; Uniprot ID:GP114_HUMAN; ENSEMBL ID: ENSG00000159618; HGNC ID:
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body0 / 707610 
blastocyst0 / 623190 
fetus4 / 5640127
neonate0 / 310970 
infant0 / 236200 
juvenile0 / 555560 
adult13 / 19391216
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma0 / 174750 
breast (mammary gland) tumor0 / 941780 
cervical tumor0 / 343660 
chondrosarcoma1 / 8282312
colorectal tumor2 / 11424617
esophageal tumor0 / 172900 
gastrointestinal tumor0 / 1193690 
germ cell tumor3 / 26384511
glioma0 / 1068830 
head and neck tumor0 / 1363020 
kidney tumor0 / 689590 
leukemia1 / 9584210
liver tumor0 / 963590 
lung tumor0 / 1031270 
lymphoma1 / 7175513
non-neoplasia2 / 9725020
normal34 / 336030710
ovarian tumor0 / 766820 
pancreatic tumor0 / 1046160 
primitive neuroectodermal tumor of the CNS0 / 1256800 
prostate cancer0 / 1026800 
retinoblastoma0 / 463560 
skin tumor0 / 1249490 
soft tissue/muscle tissue tumor0 / 1251910 
uterine tumor0 / 902570 
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland0 / 331970 
ascites0 / 400150 
bladder0 / 297570 
blood1 / 1234788
bone0 / 716550 
bone marrow4 / 4880181
brain6 / 11009895
cervix0 / 481710 
connective tissue3 / 14925520
ear0 / 162120 
embryonic tissue0 / 2157220 
esophagus0 / 202090 
eye0 / 2110540 
heart1 / 8962611
intestine6 / 23447225
kidney4 / 21177718
larynx0 / 241450 
liver0 / 2077430 
lung0 / 3369740 
lymph0 / 442700 
lymph node8 / 9161087
mammary gland0 / 1532710 
mouth0 / 670520 
muscle2 / 10771518
nerve0 / 157680 
ovary0 / 1020510 
pancreas8 / 21481237
parathyroid0 / 205390 
pharynx0 / 413280 
pituitary gland0 / 165850 
placenta0 / 2808250 
prostate1 / 1893455
salivary gland0 / 201550 
skin0 / 2105740 
spleen1 / 5395218
stomach0 / 966190 
testis1 / 3304423
thymus4 / 8113149
thyroid0 / 474730 
tonsil1 / 1699958
trachea1 / 5241319
umbilical cord0 / 136800 
uterus0 / 2328780 
vascular0 / 517800 
Microarray in BioGPS Top
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: A_23_P206293
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala2.11 ± 1.13
Basal Forebrain1.66 ± 0.4
Basal Part of Pons1.31 ± 0.36
Cerebellar Cortex1.51 ± 0.76
Cerebellar Nuclei2.16 ± 1.03
Claustrum2.58 ± 0.72
Epithalamus1.45 ± 0.79
Frontal Lobe1.59 ± 0.89
Globus Pallidus2.52 ± 0.72
Hypothalamus1.68 ± 0.75
Insula1.51 ± 0.59
Limbic Lobe1.75 ± 0.8
Mesencephalon1.95 ± 0.96
Myelencephalon1.75 ± 0.85
Occipital Lobe1.7 ± 0.56
Parietal Lobe1.73 ± 0.9
Pontine Tegmentum1.75 ± 0.75
Striatum1.85 ± 0.77
Subthalamus1.79 ± 0.65
Temporal Lobe1.61 ± 0.7
Thalamus1.67 ± 0.75
White Matter1.98 ± 0.12
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Gpr114CBCerebellum0.33
1.08
Gpr114CTXCerebral cortex0.48
0.76
Gpr114HIPHippocampal region0.23
0.29
Gpr114HPFHippocampal formation0.25
0.35
Gpr114HYHypothalamus0.04
0.07
Gpr114LSXLateral septal complex0.15
0.22
Gpr114MBMidbrain0.31
0.54
Gpr114MYMedulla1.35
1.88
Gpr114OLFOlfactory bulb0.85
2.55
Gpr114PPons0.22
0.46
Gpr114PALPallidum0.07
0.08
Gpr114RHPRetrohippocampal region0.3
0.45
Gpr114sAMYStriatum-like amygdalar nuclei0.11
0.1
Gpr114STRStriatum0.31
0.32
Gpr114STRdStriatum dorsal region0.44
0.47
Gpr114STRvStriatum ventral region0.1
0.09
Gpr114THThalamus0.22
0.23
Peptide Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018