AutismKB 2.0

Annotation Detail for C6orf170


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Basic Information Top
Gene Symbol:C6orf170 ( BROMI,C6orf171,FLJ30899,FLJ34235,bA301B7.2,bA57L9.1,dJ310J6.1 )
Gene Full Name: chromosome 6 open reading frame 170
Band: 6q22.31
Quick LinksEntrez ID:221322; OMIM: NA; Uniprot ID:BROMI_HUMAN; ENSEMBL ID: ENSG00000146350; HGNC ID:
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body1 / 7076114
blastocyst3 / 6231948
fetus11 / 56401219
neonate0 / 310970 
infant0 / 236200 
juvenile0 / 555560 
adult18 / 19391219
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor1 / 1279478
bladder carcinoma0 / 174750 
breast (mammary gland) tumor1 / 9417810
cervical tumor0 / 343660 
chondrosarcoma0 / 828230 
colorectal tumor0 / 1142460 
esophageal tumor0 / 172900 
gastrointestinal tumor0 / 1193690 
germ cell tumor4 / 26384515
glioma0 / 1068830 
head and neck tumor7 / 13630251
kidney tumor0 / 689590 
leukemia0 / 958420 
liver tumor1 / 9635910
lung tumor1 / 1031279
lymphoma0 / 717550 
non-neoplasia0 / 972500 
normal39 / 336030711
ovarian tumor0 / 766820 
pancreatic tumor0 / 1046160 
primitive neuroectodermal tumor of the CNS0 / 1256800 
prostate cancer0 / 1026800 
retinoblastoma0 / 463560 
skin tumor0 / 1249490 
soft tissue/muscle tissue tumor0 / 1251910 
uterine tumor1 / 9025711
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland1 / 3319730
ascites0 / 400150 
bladder0 / 297570 
blood0 / 1234780 
bone0 / 716550 
bone marrow0 / 488010 
brain21 / 110098919
cervix0 / 481710 
connective tissue0 / 1492550 
ear0 / 162120 
embryonic tissue4 / 21572218
esophagus0 / 202090 
eye0 / 2110540 
heart0 / 896260 
intestine1 / 2344724
kidney0 / 2117770 
larynx7 / 24145289
liver4 / 20774319
lung1 / 3369742
lymph0 / 442700 
lymph node4 / 9161043
mammary gland1 / 1532716
mouth0 / 670520 
muscle0 / 1077150 
nerve0 / 157680 
ovary1 / 1020519
pancreas0 / 2148120 
parathyroid1 / 2053948
pharynx0 / 413280 
pituitary gland0 / 165850 
placenta2 / 2808257
prostate0 / 1893450 
salivary gland0 / 201550 
skin0 / 2105740 
spleen0 / 539520 
stomach0 / 966190 
testis7 / 33044221
thymus0 / 811310 
thyroid0 / 474730 
tonsil0 / 169990 
trachea6 / 52413114
umbilical cord0 / 136800 
uterus2 / 2328788
vascular0 / 517800 
Microarray in BioGPS Top
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: A_23_P326325
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala3.88 ± 0.52
Basal Forebrain3.72 ± 0.42
Basal Part of Pons3.58 ± 0.48
Cerebellar Cortex3.52 ± 0.48
Cerebellar Nuclei3.5 ± 0.44
Claustrum3.72 ± 0.73
Epithalamus3.98 ± 0.37
Frontal Lobe3.62 ± 0.51
Globus Pallidus3.28 ± 0.37
Hypothalamus3.69 ± 0.65
Insula3.61 ± 0.47
Limbic Lobe3.76 ± 0.45
Mesencephalon3.82 ± 0.5
Myelencephalon3.7 ± 0.48
Occipital Lobe3.87 ± 0.41
Parietal Lobe3.74 ± 0.45
Pontine Tegmentum3.76 ± 0.53
Striatum4.05 ± 0.41
Subthalamus3.43 ± 0.44
Temporal Lobe3.83 ± 0.44
Thalamus3.48 ± 0.43
White Matter3.96 ± 0.31
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
D630037F22RikCBCerebellum0.51
0.94
D630037F22RikCTXCerebral cortex0.29
0.49
D630037F22RikHIPHippocampal region0.33
0.39
D630037F22RikHPFHippocampal formation0.25
0.32
D630037F22RikHYHypothalamus0.03
0.1
D630037F22RikLSXLateral septal complex0
0
D630037F22RikMBMidbrain0.26
0.45
D630037F22RikMYMedulla0.18
0.27
D630037F22RikOLFOlfactory bulb0.44
1.3
D630037F22RikPPons0.1
0.2
D630037F22RikPALPallidum0.07
0.04
D630037F22RikRHPRetrohippocampal region0.1
0.11
D630037F22RiksAMYStriatum-like amygdalar nuclei0.04
0
D630037F22RikSTRStriatum0.08
0.1
D630037F22RikSTRdStriatum dorsal region0.1
0.1
D630037F22RikSTRvStriatum ventral region0.1
0.19
D630037F22RikTHThalamus0.16
0.28
Peptide Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018