AutismKB 2.0

Annotation Detail for GPR115


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Basic Information Top
Gene Symbol:GPR115 ( FLJ38076,PGR18 )
Gene Full Name: G protein-coupled receptor 115
Band: 6p12.3
Quick LinksEntrez ID:221393; OMIM: NA; Uniprot ID:GP115_HUMAN; ENSEMBL ID: ENSG00000153294; HGNC ID:
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body0 / 707610 
blastocyst0 / 623190 
fetus3 / 5640125
neonate0 / 310970 
infant0 / 236200 
juvenile0 / 555560 
adult15 / 19391217
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma2 / 17475114
breast (mammary gland) tumor0 / 941780 
cervical tumor0 / 343660 
chondrosarcoma0 / 828230 
colorectal tumor0 / 1142460 
esophageal tumor1 / 1729057
gastrointestinal tumor0 / 1193690 
germ cell tumor0 / 2638450 
glioma0 / 1068830 
head and neck tumor4 / 13630229
kidney tumor0 / 689590 
leukemia0 / 958420 
liver tumor0 / 963590 
lung tumor0 / 1031270 
lymphoma0 / 717550 
non-neoplasia2 / 9725020
normal20 / 33603075
ovarian tumor0 / 766820 
pancreatic tumor0 / 1046160 
primitive neuroectodermal tumor of the CNS0 / 1256800 
prostate cancer0 / 1026800 
retinoblastoma0 / 463560 
skin tumor0 / 1249490 
soft tissue/muscle tissue tumor0 / 1251910 
uterine tumor0 / 902570 
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland0 / 331970 
ascites0 / 400150 
bladder0 / 297570 
blood0 / 1234780 
bone0 / 716550 
bone marrow0 / 488010 
brain0 / 11009890 
cervix0 / 481710 
connective tissue0 / 1492550 
ear0 / 162120 
embryonic tissue0 / 2157220 
esophagus1 / 2020949
eye1 / 2110544
heart3 / 8962633
intestine0 / 2344720 
kidney0 / 2117770 
larynx0 / 241450 
liver0 / 2077430 
lung1 / 3369742
lymph0 / 442700 
lymph node0 / 916100 
mammary gland1 / 1532716
mouth4 / 6705259
muscle0 / 1077150 
nerve0 / 157680 
ovary0 / 1020510 
pancreas0 / 2148120 
parathyroid0 / 205390 
pharynx0 / 413280 
pituitary gland0 / 165850 
placenta2 / 2808257
prostate0 / 1893450 
salivary gland0 / 201550 
skin2 / 2105749
spleen0 / 539520 
stomach0 / 966190 
testis0 / 3304420 
thymus0 / 811310 
thyroid0 / 474730 
tonsil0 / 169990 
trachea0 / 524130 
umbilical cord0 / 136800 
uterus8 / 23287834
vascular3 / 5178057
Microarray in BioGPS Top
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: A_23_P7866
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala2.34 ± 1.04
Basal Forebrain1.97 ± 0.44
Basal Part of Pons1.78 ± 0.41
Cerebellar Cortex1.9 ± 0.61
Cerebellar Nuclei2.33 ± 0.83
Claustrum2.7 ± 0.81
Epithalamus1.77 ± 0.8
Frontal Lobe1.86 ± 0.6
Globus Pallidus2.49 ± 0.59
Hypothalamus1.92 ± 0.61
Insula1.78 ± 0.4
Limbic Lobe2.06 ± 0.67
Mesencephalon2.11 ± 0.72
Myelencephalon2.05 ± 0.65
Occipital Lobe2.22 ± 0.83
Parietal Lobe2.04 ± 0.76
Pontine Tegmentum2 ± 0.64
Striatum2.11 ± 0.64
Subthalamus2.1 ± 0.71
Temporal Lobe1.9 ± 0.63
Thalamus1.94 ± 0.59
White Matter2.32 ± 0.18
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Gpr115CBCerebellum0.48
0.84
Gpr115CTXCerebral cortex0.48
0.64
Gpr115HIPHippocampal region0.46
0.76
Gpr115HPFHippocampal formation0.4
0.57
Gpr115HYHypothalamus1.5
2.07
Gpr115LSXLateral septal complex0.2
0.36
Gpr115MBMidbrain0.51
0.87
Gpr115MYMedulla0.58
0.68
Gpr115OLFOlfactory bulb1.15
1.05
Gpr115PPons0.25
0.38
Gpr115PALPallidum0.17
0.18
Gpr115RHPRetrohippocampal region0.29
0.33
Gpr115sAMYStriatum-like amygdalar nuclei1.25
1.51
Gpr115STRStriatum0.56
0.73
Gpr115STRdStriatum dorsal region0.6
0.78
Gpr115STRvStriatum ventral region0.23
0.3
Gpr115THThalamus0.79
1.15
Peptide Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018