AutismKB 2.0

Annotation Detail for GPR116


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Basic Information Top
Gene Symbol:GPR116 ( DKFZp564O1923,FLJ90640,KIAA0758,KPG_001 )
Gene Full Name: G protein-coupled receptor 116
Band: 6p12.3
Quick LinksEntrez ID:221395; OMIM: NA; Uniprot ID:GP116_HUMAN; ENSEMBL ID: ENSG00000069122; HGNC ID:
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body0 / 707610 
blastocyst0 / 623190 
fetus29 / 56401251
neonate0 / 310970 
infant0 / 236200 
juvenile0 / 555560 
adult74 / 193912138
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma0 / 174750 
breast (mammary gland) tumor1 / 9417810
cervical tumor0 / 343660 
chondrosarcoma6 / 8282372
colorectal tumor2 / 11424617
esophageal tumor0 / 172900 
gastrointestinal tumor4 / 11936933
germ cell tumor1 / 2638453
glioma8 / 10688374
head and neck tumor11 / 13630280
kidney tumor2 / 6895929
leukemia0 / 958420 
liver tumor0 / 963590 
lung tumor0 / 1031270 
lymphoma0 / 717550 
non-neoplasia0 / 972500 
normal137 / 336030740
ovarian tumor2 / 7668226
pancreatic tumor1 / 1046169
primitive neuroectodermal tumor of the CNS0 / 1256800 
prostate cancer0 / 1026800 
retinoblastoma0 / 463560 
skin tumor0 / 1249490 
soft tissue/muscle tissue tumor0 / 1251910 
uterine tumor1 / 9025711
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue1 / 1310676
adrenal gland0 / 331970 
ascites0 / 400150 
bladder0 / 297570 
blood0 / 1234780 
bone1 / 7165513
bone marrow0 / 488010 
brain27 / 110098924
cervix0 / 481710 
connective tissue7 / 14925546
ear0 / 162120 
embryonic tissue0 / 2157220 
esophagus0 / 202090 
eye3 / 21105414
heart3 / 8962633
intestine4 / 23447217
kidney23 / 211777108
larynx0 / 241450 
liver5 / 20774324
lung19 / 33697456
lymph0 / 442700 
lymph node0 / 916100 
mammary gland4 / 15327126
mouth4 / 6705259
muscle5 / 10771546
nerve0 / 157680 
ovary0 / 1020510 
pancreas5 / 21481223
parathyroid0 / 205390 
pharynx2 / 4132848
pituitary gland0 / 165850 
placenta18 / 28082564
prostate0 / 1893450 
salivary gland0 / 201550 
skin0 / 2105740 
spleen5 / 5395292
stomach4 / 9661941
testis6 / 33044218
thymus0 / 811310 
thyroid9 / 47473189
tonsil0 / 169990 
trachea2 / 5241338
umbilical cord0 / 136800 
uterus13 / 23287855
vascular1 / 5178019
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 212950_at
Cell line Expression level Expression bar
721_B_lymphoblasts5.95
Adipocyte5.95
AdrenalCortex14.7
Adrenalgland6.2
Amygdala6.7
Appendix9.2
AtrioventricularNode5.35
BDCA4+_DentriticCells5.45
Bonemarrow6.45
BronchialEpithelialCells5.75
CD105+_Endothelial6.4
CD14+_Monocytes5.9
CD19+_BCells(neg._sel.)6.1
CD33+_Myeloid7.45
CD34+6.9
CD4+_Tcells5.55
CD56+_NKCells6.4
CD71+_EarlyErythroid5.45
CD8+_Tcells4.95
CardiacMyocytes8.8
Caudatenucleus5.9
Cerebellum5.2
CerebellumPeduncles7.45
CiliaryGanglion6.7
CingulateCortex7.9
Colorectaladenocarcinoma5.8
DorsalRootGanglion5.95
FetalThyroid14.85
Fetalbrain6.4
Fetalliver5.65
Fetallung312.65
GlobusPallidus5.15
Heart8.7
Hypothalamus7.6
Kidney14.3
Leukemia_chronicMyelogenousK-5624.9
Leukemia_promyelocytic-HL-604.85
Leukemialymphoblastic(MOLT-4)4.6
Liver8.75
Lung31.2
Lymphnode13.55
Lymphoma_burkitts(Daudi)7.6
Lymphoma_burkitts(Raji)8.45
MedullaOblongata6.25
OccipitalLobe9.3
OlfactoryBulb10.05
Ovary4.35
Pancreas5.8
PancreaticIslet7.8
ParietalLobe6.95
Pituitary10.7
Placenta16.55
Pons6.15
PrefrontalCortex8.5
Prostate7.2
Salivarygland5.3
SkeletalMuscle9.65
Skin8.7
SmoothMuscle6.8
Spinalcord6.65
SubthalamicNucleus6.5
SuperiorCervicalGanglion9.3
TemporalLobe5.9
Testis5.2
TestisGermCell6.95
TestisIntersitial6.65
TestisLeydigCell6.9
TestisSeminiferousTubule5.95
Thalamus6.65
Thymus4.7
Thyroid18.1
Tongue7.3
Tonsil6.3
Trachea5.4
TrigeminalGanglion6.95
Uterus13.45
UterusCorpus7.4
WholeBlood6.45
Wholebrain5.6
colon6.05
pineal_day7.62
pineal_night7.48
retina15.9
small_intestine6.05
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: CUST_290_PI416408490
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala6.72 ± 0.36
Basal Forebrain6.92 ± 0.22
Basal Part of Pons7.01 ± 0.27
Cerebellar Cortex6.75 ± 0.24
Cerebellar Nuclei8.23 ± 0.16
Claustrum6.36 ± 0.6
Epithalamus6.7 ± 0.68
Frontal Lobe7.46 ± 0.48
Globus Pallidus8.04 ± 0.35
Hypothalamus6.85 ± 0.63
Insula7.62 ± 0.29
Limbic Lobe7.11 ± 0.5
Mesencephalon7.36 ± 0.52
Myelencephalon7.33 ± 0.55
Occipital Lobe7.04 ± 0.46
Parietal Lobe7 ± 0.53
Pontine Tegmentum7.44 ± 0.6
Striatum7.93 ± 0.37
Subthalamus7.74 ± 0.27
Temporal Lobe7.36 ± 0.33
Thalamus7.46 ± 0.42
White Matter7.12 ± 0.7
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Gpr116CBCerebellum4.47
5.26
Gpr116CTXCerebral cortex5.15
4.14
Gpr116HIPHippocampal region2.87
2.91
Gpr116HPFHippocampal formation2.52
2.48
Gpr116HYHypothalamus3.25
3.09
Gpr116LSXLateral septal complex3.15
3.24
Gpr116MBMidbrain3.24
3.32
Gpr116MYMedulla4.83
5.12
Gpr116OLFOlfactory bulb6.89
5.76
Gpr116PPons4.58
5.25
Gpr116PALPallidum4.48
4.65
Gpr116RHPRetrohippocampal region1.77
1.73
Gpr116sAMYStriatum-like amygdalar nuclei1.53
1.14
Gpr116STRStriatum3.96
3.49
Gpr116STRdStriatum dorsal region3.6
3.25
Gpr116STRvStriatum ventral region6.99
5.46
Gpr116THThalamus14.98
13.87
Peptide Top
Peptide Name Peptide Lengh Peptide Start Peptide End Peptide Sequence Source
PAp00092492 19 689 707 FSNVPSSPESPIGGTITYK Peptide Atlas

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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