AutismKB 2.0

Annotation Detail for KIF6


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Basic Information Top
Gene Symbol:KIF6 ( C6orf102,DKFZp451I2418,MGC33317,dJ1043E3.1,dJ137F1.4,dJ188D3.1 )
Gene Full Name: kinesin family member 6
Band: 6p21.2
Quick LinksEntrez ID:221458; OMIM: NA; Uniprot ID:KIF6_HUMAN; ENSEMBL ID: ENSG00000164627; HGNC ID: 21202
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body0 / 707610 
blastocyst0 / 623190 
fetus10 / 56401217
neonate0 / 310970 
infant0 / 236200 
juvenile0 / 555560 
adult7 / 19391213
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma0 / 174750 
breast (mammary gland) tumor0 / 941780 
cervical tumor0 / 343660 
chondrosarcoma0 / 828230 
colorectal tumor0 / 1142460 
esophageal tumor0 / 172900 
gastrointestinal tumor0 / 1193690 
germ cell tumor0 / 2638450 
glioma2 / 10688318
head and neck tumor0 / 1363020 
kidney tumor0 / 689590 
leukemia0 / 958420 
liver tumor0 / 963590 
lung tumor1 / 1031279
lymphoma0 / 717550 
non-neoplasia1 / 9725010
normal21 / 33603076
ovarian tumor0 / 766820 
pancreatic tumor0 / 1046160 
primitive neuroectodermal tumor of the CNS0 / 1256800 
prostate cancer0 / 1026800 
retinoblastoma0 / 463560 
skin tumor2 / 12494916
soft tissue/muscle tissue tumor2 / 12519115
uterine tumor0 / 902570 
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland0 / 331970 
ascites0 / 400150 
bladder0 / 297570 
blood0 / 1234780 
bone0 / 716550 
bone marrow0 / 488010 
brain9 / 11009898
cervix0 / 481710 
connective tissue2 / 14925513
ear0 / 162120 
embryonic tissue0 / 2157220 
esophagus0 / 202090 
eye2 / 2110549
heart0 / 896260 
intestine2 / 2344728
kidney0 / 2117770 
larynx0 / 241450 
liver1 / 2077434
lung2 / 3369745
lymph0 / 442700 
lymph node0 / 916100 
mammary gland0 / 1532710 
mouth0 / 670520 
muscle0 / 1077150 
nerve0 / 157680 
ovary0 / 1020510 
pancreas0 / 2148120 
parathyroid0 / 205390 
pharynx1 / 4132824
pituitary gland0 / 165850 
placenta0 / 2808250 
prostate0 / 1893450 
salivary gland0 / 201550 
skin2 / 2105749
spleen0 / 539520 
stomach0 / 966190 
testis3 / 3304429
thymus0 / 811310 
thyroid0 / 474730 
tonsil0 / 169990 
trachea0 / 524130 
umbilical cord0 / 136800 
uterus0 / 2328780 
vascular0 / 517800 
Microarray in BioGPS Top
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: A_24_P297816
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala3.05 ± 1.08
Basal Forebrain3.06 ± 0.73
Basal Part of Pons2.61 ± 0.68
Cerebellar Cortex2.24 ± 0.53
Cerebellar Nuclei2.9 ± 0.58
Claustrum3.09 ± 0.63
Epithalamus4.15 ± 0.82
Frontal Lobe2.75 ± 0.84
Globus Pallidus4.11 ± 0.46
Hypothalamus2.64 ± 0.78
Insula2.53 ± 0.54
Limbic Lobe2.62 ± 0.76
Mesencephalon2.93 ± 0.7
Myelencephalon2.85 ± 0.83
Occipital Lobe2.67 ± 0.78
Parietal Lobe2.79 ± 0.85
Pontine Tegmentum2.84 ± 0.79
Striatum3.46 ± 0.63
Subthalamus3.02 ± 0.89
Temporal Lobe2.55 ± 0.74
Thalamus2.82 ± 0.68
White Matter5.82 ± 0.29
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Kif6CBCerebellum0.4
0.73
Kif6CTXCerebral cortex0.28
0.32
Kif6HIPHippocampal region0.62
0.65
Kif6HPFHippocampal formation0.67
0.97
Kif6HYHypothalamus0.35
0.33
Kif6LSXLateral septal complex0.06
0
Kif6MBMidbrain0.26
0.48
Kif6MYMedulla0.25
0.41
Kif6OLFOlfactory bulb0.42
0.3
Kif6PPons0.18
0.32
Kif6PALPallidum0.13
0.25
Kif6RHPRetrohippocampal region0.71
1.27
Kif6sAMYStriatum-like amygdalar nuclei0.17
0.23
Kif6STRStriatum0.09
0.08
Kif6STRdStriatum dorsal region0.09
0.1
Kif6STRvStriatum ventral region0.04
0.02
Kif6THThalamus0.31
0.42
Peptide Top
Peptide Name Peptide Lengh Peptide Start Peptide End Peptide Sequence Source
KIF6_HUMAN_286 7 286 292 ALSEKHR PRIDE

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018