AutismKB 2.0

Annotation Detail for C6orf136


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Basic Information Top
Gene Symbol:C6orf136 ( MGC15854 )
Gene Full Name: chromosome 6 open reading frame 136
Band: 6p21.33
Quick LinksEntrez ID:221545; OMIM: NA; Uniprot ID:CF136_HUMAN; ENSEMBL ID: ENSG00000204564; HGNC ID: 21301
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body0 / 707610 
blastocyst2 / 6231932
fetus13 / 56401223
neonate0 / 310970 
infant1 / 2362042
juvenile1 / 5555617
adult35 / 193912118
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma0 / 174750 
breast (mammary gland) tumor1 / 9417810
cervical tumor0 / 343660 
chondrosarcoma1 / 8282312
colorectal tumor1 / 1142468
esophageal tumor0 / 172900 
gastrointestinal tumor3 / 11936925
germ cell tumor1 / 2638453
glioma2 / 10688318
head and neck tumor2 / 13630214
kidney tumor1 / 6895914
leukemia5 / 9584252
liver tumor1 / 9635910
lung tumor2 / 10312719
lymphoma1 / 7175513
non-neoplasia0 / 972500 
normal62 / 336030718
ovarian tumor0 / 766820 
pancreatic tumor0 / 1046160 
primitive neuroectodermal tumor of the CNS1 / 1256807
prostate cancer0 / 1026800 
retinoblastoma0 / 463560 
skin tumor3 / 12494924
soft tissue/muscle tissue tumor1 / 1251917
uterine tumor3 / 9025733
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland1 / 3319730
ascites1 / 4001524
bladder0 / 297570 
blood6 / 12347848
bone0 / 716550 
bone marrow0 / 488010 
brain25 / 110098922
cervix0 / 481710 
connective tissue1 / 1492556
ear0 / 162120 
embryonic tissue2 / 2157229
esophagus0 / 202090 
eye5 / 21105423
heart2 / 8962622
intestine2 / 2344728
kidney6 / 21177728
larynx0 / 241450 
liver2 / 2077439
lung9 / 33697426
lymph0 / 442700 
lymph node3 / 9161032
mammary gland1 / 1532716
mouth2 / 6705229
muscle4 / 10771537
nerve0 / 157680 
ovary0 / 1020510 
pancreas6 / 21481227
parathyroid1 / 2053948
pharynx0 / 413280 
pituitary gland0 / 165850 
placenta2 / 2808257
prostate2 / 18934510
salivary gland0 / 201550 
skin3 / 21057414
spleen1 / 5395218
stomach2 / 9661920
testis1 / 3304423
thymus0 / 811310 
thyroid0 / 474730 
tonsil0 / 169990 
trachea0 / 524130 
umbilical cord0 / 136800 
uterus5 / 23287821
vascular0 / 517800 
Microarray in BioGPS Top
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: A_23_P300826
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala7.35 ± 0.47
Basal Forebrain7.69 ± 0.19
Basal Part of Pons8.25 ± 0.3
Cerebellar Cortex8.09 ± 0.22
Cerebellar Nuclei8.43 ± 0.3
Claustrum7.54 ± 0.43
Epithalamus7.52 ± 0.29
Frontal Lobe8.04 ± 0.33
Globus Pallidus7.15 ± 0.3
Hypothalamus7.89 ± 0.3
Insula7.92 ± 0.24
Limbic Lobe7.65 ± 0.47
Mesencephalon7.71 ± 0.47
Myelencephalon7.78 ± 0.46
Occipital Lobe7.52 ± 0.48
Parietal Lobe7.92 ± 0.4
Pontine Tegmentum7.87 ± 0.38
Striatum7.28 ± 0.36
Subthalamus8.39 ± 0.24
Temporal Lobe7.94 ± 0.33
Thalamus7.95 ± 0.35
White Matter7.08 ± 0.55
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
2310061I04RikCBCerebellum88.44
100
2310061I04RikCTXCerebral cortex92.6
74.82
2310061I04RikHIPHippocampal region49.98
70.22
2310061I04RikHPFHippocampal formation66.11
73.83
2310061I04RikHYHypothalamus76.1
65
2310061I04RikLSXLateral septal complex69.3
50.74
2310061I04RikMBMidbrain85.36
85.3
2310061I04RikMYMedulla88.22
100
2310061I04RikOLFOlfactory bulb81.63
75.57
2310061I04RikPPons84.62
100
2310061I04RikPALPallidum84.44
85.24
2310061I04RikRHPRetrohippocampal region91.39
79.23
2310061I04RiksAMYStriatum-like amygdalar nuclei83.12
67.17
2310061I04RikSTRStriatum71
53.72
2310061I04RikSTRdStriatum dorsal region69.76
53.17
2310061I04RikSTRvStriatum ventral region77.24
55.45
2310061I04RikTHThalamus79.44
72.3
Peptide Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018