Annotation Detail for KDM1B
Basic Information Top
| Gene Symbol: | KDM1B ( AOF1,C6orf193,DKFZp686I0412,FLJ33898,FLJ34109,FLJ43328,LSD2,bA204B7.3,dJ298J15.2 ) |
|---|---|
| Gene Full Name: | lysine (K)-specific demethylase 1B |
| Band: | 6p22.3 |
| Quick Links | Entrez ID:221656; OMIM: 613081; Uniprot ID:KDM1B_HUMAN; ENSEMBL ID: ENSG00000165097; HGNC ID: 21577 |
| Relate to Another Database: | SFARIGene; denovo-db |
- Unigene ID: Hs.709336
| Pool Name | Gene EST/Total EST in pool | Transcripts per million(TPM) | Bar based on TPM |
|---|---|---|---|
 | |||
| embryoid body | 2 / 70761 | 28 |  |
| blastocyst | 0 / 62319 | 0 | |
| fetus | 17 / 564012 | 30 | |
| neonate | 0 / 31097 | 0 | |
| infant | 0 / 23620 | 0 | |
| juvenile | 0 / 55556 | 0 | |
| adult | 57 / 1939121 | 29 | |
| Pool Name | Gene EST/Total EST in pool | Transcripts per million(TPM) | Bar based on TPM |
|---|---|---|---|
| |||
| adrenal tumor | 0 / 12794 | 0 | |
| bladder carcinoma | 0 / 17475 | 0 | |
| breast (mammary gland) tumor | 1 / 94178 | 10 |  |
| cervical tumor | 2 / 34366 | 58 |  |
| chondrosarcoma | 1 / 82823 | 12 | |
| colorectal tumor | 2 / 114246 | 17 | |
| esophageal tumor | 0 / 17290 | 0 | |
| gastrointestinal tumor | 5 / 119369 | 41 | |
| germ cell tumor | 2 / 263845 | 7 | |
| glioma | 0 / 106883 | 0 | |
| head and neck tumor | 7 / 136302 | 51 | |
| kidney tumor | 1 / 68959 | 14 | |
| leukemia | 14 / 95842 | 146 | |
| liver tumor | 0 / 96359 | 0 | |
| lung tumor | 0 / 103127 | 0 | |
| lymphoma | 1 / 71755 | 13 | |
| non-neoplasia | 0 / 97250 | 0 | |
| normal | 69 / 3360307 | 20 | |
| ovarian tumor | 1 / 76682 | 13 | |
| pancreatic tumor | 1 / 104616 | 9 | |
| primitive neuroectodermal tumor of the CNS | 0 / 125680 | 0 | |
| prostate cancer | 0 / 102680 | 0 | |
| retinoblastoma | 0 / 46356 | 0 | |
| skin tumor | 2 / 124949 | 16 | |
| soft tissue/muscle tissue tumor | 3 / 125191 | 23 | |
| uterine tumor | 2 / 90257 | 22 | |
| Pool Name | Gene EST/Total EST in pool | Transcripts per million(TPM) | Bar based on TPM |
|---|---|---|---|
| |||
| adipose tissue | 0 / 13106 | 0 | |
| adrenal gland | 0 / 33197 | 0 | |
| ascites | 0 / 40015 | 0 | |
| bladder | 1 / 29757 | 33 | |
| blood | 13 / 123478 | 105 | |
| bone | 1 / 71655 | 13 | |
| bone marrow | 0 / 48801 | 0 | |
| brain | 14 / 1100989 | 12 | |
| cervix | 2 / 48171 | 41 | |
| connective tissue | 3 / 149255 | 20 | |
| ear | 0 / 16212 | 0 | |
| embryonic tissue | 4 / 215722 | 18 | |
| esophagus | 0 / 20209 | 0 | |
| eye | 9 / 211054 | 42 | |
| heart | 1 / 89626 | 11 | |
| intestine | 12 / 234472 | 51 | |
| kidney | 2 / 211777 | 9 | |
| larynx | 0 / 24145 | 0 | |
| liver | 1 / 207743 | 4 | |
| lung | 16 / 336974 | 47 | |
| lymph | 1 / 44270 | 22 | |
| lymph node | 8 / 91610 | 87 | |
| mammary gland | 5 / 153271 | 32 | |
| mouth | 2 / 67052 | 29 | |
| muscle | 2 / 107715 | 18 | |
| nerve | 0 / 15768 | 0 | |
| ovary | 1 / 102051 | 9 | |
| pancreas | 1 / 214812 | 4 | |
| parathyroid | 0 / 20539 | 0 | |
| pharynx | 0 / 41328 | 0 | |
| pituitary gland | 0 / 16585 | 0 | |
| placenta | 1 / 280825 | 3 | |
| prostate | 2 / 189345 | 10 | |
| salivary gland | 0 / 20155 | 0 | |
| skin | 3 / 210574 | 14 | |
| spleen | 1 / 53952 | 18 | |
| stomach | 2 / 96619 | 20 | |
| testis | 4 / 330442 | 12 | |
| thymus | 0 / 81131 | 0 | |
| thyroid | 6 / 47473 | 126 | |
| tonsil | 0 / 16999 | 0 | |
| trachea | 0 / 52413 | 0 | |
| umbilical cord | 0 / 13680 | 0 | |
| uterus | 3 / 232878 | 12 | |
| vascular | 0 / 51780 | 0 |
Microarray in - Probe name: A_23_P338401
- Donor H0351.2001
- Sex: Male Age: 24 years Race/Ethnicity: African American Handedness: Left
- Tissue Receipt Date: 7/29/2009 Serology: Pass Tissue pH :6.72 Additional Medical Information :History of asthma
- Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
- Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
| Tissue | Expression(mean ± stddev) | Expression Bar |
|---|---|---|
| Amygdala | 4.44 ± 0.72 | ![](../"images/bar_3.png"){kind=small}   |
| Basal Forebrain | 3.73 ± 0.46 | |
| Basal Part of Pons | 3.67 ± 0.49 | |
| Cerebellar Cortex | 3.74 ± 0.48 | |
| Cerebellar Nuclei | 3.82 ± 0.54 | |
| Claustrum | 4.93 ± 0.7 | |
| Epithalamus | 5 ± 0.54 | |
| Frontal Lobe | 3.92 ± 0.52 | |
| Globus Pallidus | 4.31 ± 0.41 | |
| Hypothalamus | 3.65 ± 0.8 | |
| Insula | 3.92 ± 0.61 | |
| Limbic Lobe | 4.14 ± 0.51 | |
| Mesencephalon | 4.09 ± 0.55 | |
| Myelencephalon | 3.96 ± 0.59 | |
| Occipital Lobe | 3.99 ± 0.6 | |
| Parietal Lobe | 3.91 ± 0.55 | |
| Pontine Tegmentum | 4.04 ± 0.59 | |
| Striatum | 4.28 ± 0.41 | |
| Subthalamus | 3.7 ± 0.25 | |
| Temporal Lobe | 4.09 ± 0.56 | |
| Thalamus | 3.85 ± 0.51 | |
| White Matter | 4.68 ± 0.33 | |
Mouse Brain ISH 
| Gene Symbol | Brain Structure ID | Brain Structure Name | Express Desity/Level (Meatured by ISH) | Express Bar |
|---|---|---|---|---|
| Aof1 | CB | Cerebellum | 1.91 | |
| 3.36 | | |||
| Aof1 | CTX | Cerebral cortex | 2.57 | |
| 2.52 | | |||
| Aof1 | HIP | Hippocampal region | 0.27 | |
| 0.41 | | |||
| Aof1 | HPF | Hippocampal formation | 0.37 | |
| 0.6 | | |||
| Aof1 | HY | Hypothalamus | 0.24 | |
| 0.54 | | |||
| Aof1 | LSX | Lateral septal complex | 0.13 | |
| 0.12 | | |||
| Aof1 | MB | Midbrain | 0.72 | |
| 1.06 | | |||
| Aof1 | MY | Medulla | 1.05 | |
| 1.35 | | |||
| Aof1 | OLF | Olfactory bulb | 1.34 | |
| 1.32 | | |||
| Aof1 | P | Pons | 0.97 | |
| 1.41 | | |||
| Aof1 | PAL | Pallidum | 0.04 | |
| 0.12 | | |||
| Aof1 | RHP | Retrohippocampal region | 0.5 | |
| 0.82 | | |||
| Aof1 | sAMY | Striatum-like amygdalar nuclei | 0.12 | |
| 0.05 | | |||
| Aof1 | STR | Striatum | 0.15 | |
| 0.19 | | |||
| Aof1 | STRd | Striatum dorsal region | 0.13 | |
| 0.17 | | |||
| Aof1 | STRv | Striatum ventral region | 0.22 | |
| 0.3 | | |||
| Aof1 | TH | Thalamus | 0.15 | |
| 0.15 | |