AutismKB 2.0

Annotation Detail for FCN1


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Basic Information Top
Gene Symbol:FCN1 ( FCNM )
Gene Full Name: ficolin (collagen/fibrinogen domain containing) 1
Band: 9q34.3
Quick LinksEntrez ID:2219; OMIM: 601252; Uniprot ID:FCN1_HUMAN; ENSEMBL ID: ENSG00000085265; HGNC ID: 3623
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body0 / 707610 
blastocyst0 / 623190 
fetus5 / 5640128
neonate1 / 3109732
infant0 / 236200 
juvenile0 / 555560 
adult96 / 193912149
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma0 / 174750 
breast (mammary gland) tumor0 / 941780 
cervical tumor0 / 343660 
chondrosarcoma1 / 8282312
colorectal tumor1 / 1142468
esophageal tumor0 / 172900 
gastrointestinal tumor0 / 1193690 
germ cell tumor2 / 2638457
glioma0 / 1068830 
head and neck tumor1 / 1363027
kidney tumor3 / 6895943
leukemia61 / 95842636
liver tumor0 / 963590 
lung tumor0 / 1031270 
lymphoma0 / 717550 
non-neoplasia2 / 9725020
normal66 / 336030719
ovarian tumor0 / 766820 
pancreatic tumor0 / 1046160 
primitive neuroectodermal tumor of the CNS0 / 1256800 
prostate cancer0 / 1026800 
retinoblastoma0 / 463560 
skin tumor0 / 1249490 
soft tissue/muscle tissue tumor0 / 1251910 
uterine tumor0 / 902570 
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland0 / 331970 
ascites0 / 400150 
bladder0 / 297570 
blood78 / 123478631
bone3 / 7165541
bone marrow3 / 4880161
brain2 / 11009891
cervix0 / 481710 
connective tissue2 / 14925513
ear0 / 162120 
embryonic tissue0 / 2157220 
esophagus0 / 202090 
eye5 / 21105423
heart0 / 896260 
intestine3 / 23447212
kidney4 / 21177718
larynx0 / 241450 
liver0 / 2077430 
lung16 / 33697447
lymph0 / 442700 
lymph node0 / 916100 
mammary gland1 / 1532716
mouth0 / 670520 
muscle1 / 1077159
nerve0 / 157680 
ovary0 / 1020510 
pancreas1 / 2148124
parathyroid0 / 205390 
pharynx0 / 413280 
pituitary gland0 / 165850 
placenta2 / 2808257
prostate1 / 1893455
salivary gland0 / 201550 
skin0 / 2105740 
spleen1 / 5395218
stomach0 / 966190 
testis0 / 3304420 
thymus0 / 811310 
thyroid1 / 4747321
tonsil0 / 169990 
trachea1 / 5241319
umbilical cord0 / 136800 
uterus4 / 23287817
vascular1 / 5178019
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 205237_at
Cell line Expression level Expression bar
721_B_lymphoblasts5.6
Adipocyte4.7
AdrenalCortex5.15
Adrenalgland4.1
Amygdala4.95
Appendix5.1
AtrioventricularNode3.75
BDCA4+_DentriticCells1427.25
Bonemarrow1042.85
BronchialEpithelialCells4.65
CD105+_Endothelial82.3
CD14+_Monocytes6736.25
CD19+_BCells(neg._sel.)5.5
CD33+_Myeloid8469.55
CD34+9.5
CD4+_Tcells5.2
CD56+_NKCells40.05
CD71+_EarlyErythroid12.25
CD8+_Tcells4.55
CardiacMyocytes6.3
Caudatenucleus4.3
Cerebellum3.85
CerebellumPeduncles5.45
CiliaryGanglion3.55
CingulateCortex4.9
Colorectaladenocarcinoma4.8
DorsalRootGanglion3.65
FetalThyroid4.6
Fetalbrain4.75
Fetalliver4.2
Fetallung3.95
GlobusPallidus3.7
Heart8.05
Hypothalamus5
Kidney4
Leukemia_chronicMyelogenousK-5624.3
Leukemia_promyelocytic-HL-604.25
Leukemialymphoblastic(MOLT-4)3.8
Liver6.55
Lung34.75
Lymphnode4.1
Lymphoma_burkitts(Daudi)6.15
Lymphoma_burkitts(Raji)6.8
MedullaOblongata4.3
OccipitalLobe4.25
OlfactoryBulb3.7
Ovary3.25
Pancreas3.9
PancreaticIslet5.1
ParietalLobe5.1
Pituitary5.6
Placenta4.9
Pons4.6
PrefrontalCortex5.85
Prostate5.55
Salivarygland3.85
SkeletalMuscle6.1
Skin3.75
SmoothMuscle5.3
Spinalcord5.1
SubthalamicNucleus4.4
SuperiorCervicalGanglion6.1
TemporalLobe4.4
Testis4.1
TestisGermCell3.9
TestisIntersitial4.05
TestisLeydigCell4.7
TestisSeminiferousTubule4.1
Thalamus4.9
Thymus3.8
Thyroid5.95
Tongue4.8
Tonsil4.65
Trachea4
TrigeminalGanglion5.05
Uterus3.9
UterusCorpus4.3
WholeBlood3637.85
Wholebrain4
colon4.85
pineal_day5.9
pineal_night5.8
retina5.85
small_intestine4.65
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: A_24_P263793
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala2.71 ± 1.03
Basal Forebrain2.25 ± 0.62
Basal Part of Pons1.91 ± 0.48
Cerebellar Cortex2.07 ± 0.72
Cerebellar Nuclei2.7 ± 0.71
Claustrum3.35 ± 0.81
Epithalamus1.93 ± 0.67
Frontal Lobe2.12 ± 0.78
Globus Pallidus3.06 ± 0.71
Hypothalamus2.24 ± 1.05
Insula2.06 ± 0.69
Limbic Lobe2.34 ± 0.81
Mesencephalon2.49 ± 0.83
Myelencephalon2.36 ± 0.82
Occipital Lobe2.25 ± 0.82
Parietal Lobe2.42 ± 0.94
Pontine Tegmentum2.44 ± 0.86
Striatum2.57 ± 0.77
Subthalamus2.39 ± 1.05
Temporal Lobe2.29 ± 0.87
Thalamus2.35 ± 0.74
White Matter2.72 ± 0.54
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
FcnaCBCerebellum4.13
4.37
FcnaCTXCerebral cortex6.4
4.51
FcnaHIPHippocampal region3.45
3.07
FcnaHPFHippocampal formation3.05
2.5
FcnaHYHypothalamus4
3.74
FcnaLSXLateral septal complex0.86
1.39
FcnaMBMidbrain5.53
7.3
FcnaMYMedulla3.12
3.65
FcnaOLFOlfactory bulb4.3
2.77
FcnaPPons2.48
3.01
FcnaPALPallidum1.82
1.4
FcnaRHPRetrohippocampal region2.58
1.88
FcnasAMYStriatum-like amygdalar nuclei3.79
2.75
FcnaSTRStriatum1.34
1
FcnaSTRdStriatum dorsal region0.87
0.66
FcnaSTRvStriatum ventral region1.87
1.23
FcnaTHThalamus3.34
2.52
Peptide Top
Peptide Name Peptide Lengh Peptide Start Peptide End Peptide Sequence Source
PAp00034035 23 237 259 GAFVGGSAGNSLTGHNNNFFSTK Peptide Atlas

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018